The RSK family of kinases: emerging roles in cellular signalling.

The 90 kDa ribosomal S6 kinase (RSK) household of proteins is a gaggle of extremely conserved Ser/Thr kinases that regulate various mobile processes, resembling cell progress, cell motility, cell survival and cell proliferation. RSKs are downstream effectors of the Ras-extramobile signal-regulated kinase (ERK)/mitogen-activated protein kinase (MAPK) signalling cascade.
Important advances within the subject of RSK and ERK/MAPK signalling have occurred prior to now few years, together with organic insights and the invention of novel substrates and new RSK regulatory mechanisms. Collectively, these information broaden the present fashions of RSK signalling and spotlight potential instructions of analysis in RSK-mediated survival, progress, proliferation and migration.

Transgenerational epigenetic inheritance: prevalence, mechanisms, and implications for the research of heredity and evolution.

This assessment describes new developments within the research of transgenerational epigenetic inheritance, a element of epigenetics. We begin by analyzing the essential ideas of the sector and the mechanisms that underlie epigenetic inheritance. We current a complete assessment of transgenerational mobile epigenetic inheritance amongst completely different taxa within the type of a desk, and focus on the information contained therein.
The evaluation of those information exhibits that epigenetic inheritance is ubiquitous and suggests strains of analysis that transcend current approaches to the topic. We conclude by exploring a number of the penalties of epigenetic inheritance for the research of evolution, whereas additionally pointing to the significance of recognizing and understanding epigenetic inheritance for sensible and theoretical points in biology.

Rules for characterizing the potential human well being results from publicity to nanomaterials: components of a screening technique.

The speedy proliferation of many various engineered nanomaterials (outlined as supplies designed and produced to have structural options with no less than one dimension of 100 nanometers or much less) presents a dilemma to regulators concerning hazard identification.
The Worldwide Life Sciences Institute Analysis Basis/Danger Science Institute convened an professional working group to develop a screening technique for the hazard identification of engineered nanomaterials. The working group report presents the weather of a screening technique somewhat than an in depth testing protocol. Primarily based on an analysis of the restricted information at the moment accessible, the report presents a broad information gathering technique relevant to this early stage within the improvement of a threat evaluation course of for nanomaterials.
Oral, dermal, inhalation, and injection routes of publicity are included recognizing that, relying on use patterns, publicity to nanomaterials might happen by any of those routes. The three key components of the toxicity screening technique are: Physicochemical Traits, In Vitro Assays (mobile and non-mobile), and In Vivo Assays. There’s a robust probability that organic exercise of nanoparticles will rely on physicochemical parameters not routinely thought-about in toxicity screening research.
Physicochemical properties which may be essential in understanding the poisonous results of take a look at supplies embody particle measurement and measurement distribution, agglomeration state, form, crystal construction, chemical composition, floor space, floor chemistry, floor cost, and porosity. In vitro strategies permit particular organic and mechanistic pathways to be remoted and examined underneath managed circumstances, in methods that aren’t possible in in vivo exams.
Checks are prompt for portal-of-entry toxicity for lungs, pores and skin, and the mucosal membranes, and goal organ toxicity for endothelium, blood, spleen, liver, nervous system, coronary heart, and kidney. Non-mobile evaluation of nanoparticle sturdiness, protein interactions, complement activation, and pro-oxidant exercise can also be thought-about.
Tier 1 in vivo assays are proposed for pulmonary, oral, pores and skin and injection exposures, and Tier 2 evaluations for pulmonary exposures are additionally proposed. Tier 1 evaluations embody markers of irritation, oxidant stress, and cell proliferation in portal-of-entry and chosen distant organs and tissues.
Tier 2 evaluations for pulmonary exposures may embody deposition, translocation, and toxicokinetics and biopersistence research; results of a number of exposures; potential results on the reproductive system, placenta, and fetus; different animal fashions; and mechanistic research.

Subtypes of medulloblastoma have distinct developmental origins.

Medulloblastoma encompasses a group of clinically and molecularly various tumour subtypes that collectively comprise the most typical malignant childhood mind tumour. These tumours are thought to come up throughout the cerebellum, with roughly 25% originating from granule neuron precursor cells (GNPCs) after aberrant activation of the Sonic Hedgehog pathway (hereafter, SHH subtype).
The pathological processes that drive heterogeneity among the many different medulloblastoma subtypes are usually not recognized, hindering the event of a lot wanted new therapies. Right here we offer proof {that a} discrete subtype of medulloblastoma that incorporates activating mutations within the WNT pathway effector CTNNB1 (hereafter, WNT subtype) arises exterior the cerebellum from cells of the dorsal brainstem.
We discovered that genes marking human WNT-subtype medulloblastomas are extra continuously expressed within the decrease rhombic lip (LRL) and embryonic dorsal brainstem than within the higher rhombic lip (URL) and growing cerebellum. Magnetic resonance imaging (MRI) and intra-operative studies confirmed that human WNT-subtype tumours infiltrate the dorsal brainstem, whereas SHH-subtype tumours are situated throughout the cerebellar hemispheres.
Activating mutations in Ctnnb1 had little influence on progenitor cell populations within the cerebellum, however induced the irregular accumulation of cells on the embryonic dorsal brainstem which included aberrantly proliferating Zic1(+) precursor cells.
These lesions endured in all mutant grownup mice; furthermore, in 15% of circumstances wherein Tp53 was concurrently deleted, they progressed to type medulloblastomas that recapitulated the anatomy and gene expression profiles of human WNT-subtype medulloblastoma.
We offer the primary proof, to our information, that subtypes of medulloblastoma have distinct mobile origins. Our information present an evidence for the marked molecular and medical variations between SHH- and WNT-subtype medulloblastomas and have profound implications for future analysis and therapy of this essential childhood most cancers.
The RSK family of kinases: emerging roles in cellular signalling.

A complete classification system for lipids.

Lipids are produced, transported, and acknowledged by the concerted actions of quite a few enzymes, binding proteins, and receptors. A complete evaluation of lipid molecules, “lipidomics,” within the context of genomics and proteomics is essential to understanding mobile physiology and pathology; consequently, lipid biology has change into a serious analysis goal of the postgenomic revolution and programs biology.
To facilitate worldwide communication about lipids, a complete classification of lipids with a standard platform that’s appropriate with informatics necessities has been developed to take care of the large quantities of information that might be generated by our lipid neighborhood.
As an preliminary step on this improvement, we divide lipids into eight classes (fatty acyls, glycerolipids, glycerophospholipids, sphingolipids, sterol lipids, prenol lipids, saccharolipids, and polyketides) containing distinct courses and subclasses of molecules, devise a standard method of representing the chemical constructions of particular person lipids and their derivatives, and supply a 12 digit identifier for every distinctive lipid molecule.

CD134

MO134CFB(V100) 100 ug
EUR 60

CD134

MO134CFB(V25) 25 ug
EUR 60

CD134

MO134F(V100) 100 ug
EUR 60

CD134

MO134F(V25) 25 ug
EUR 60

CD134

MO134F(V500) 500 ug
EUR 60

CD134

MO134PE(V100) 100 ug
EUR 60

CD134

MO134PE(V25) 25 ug
EUR 60

CD134

MO134PP(V100) 100 ug
EUR 60

CD134

MO134PP(V25) 25 ug
EUR 60

CD134

MO134PP5.5(V100) 100 ug
EUR 60

CD134

MO134PP5.5(V25) 25 ug
EUR 60

CD134

MO134PU(V100) 100 ug
EUR 60

CD134

MO134PU(V500) 500 ug
EUR 60

CD134/OX40

MBS8564766-01mL 0.1mL
EUR 345

CD134/OX40

MBS8564766-01mLAF405L 0.1mL(AF405L)
EUR 565

CD134/OX40

MBS8564766-01mLAF405S 0.1mL(AF405S)
EUR 565

CD134/OX40

MBS8564766-01mLAF610 0.1mL(AF610)
EUR 565

CD134/OX40

MBS8564766-01mLAF635 0.1mL(AF635)
EUR 565

CD134/OX40

MBS8564767-01mL 0.1mL
EUR 345

CD134/OX40

MBS8564767-01mLAF405L 0.1mL(AF405L)
EUR 565

CD134/OX40

MBS8564767-01mLAF405S 0.1mL(AF405S)
EUR 565

CD134/OX40

MBS8564767-01mLAF610 0.1mL(AF610)
EUR 565

CD134/OX40

MBS8564767-01mLAF635 0.1mL(AF635)
EUR 565

CD134 Antibody

45130-100ul 100ul
EUR 302.4

CD134 Antibody

45130-50ul 50ul
EUR 224.4

CD134 Antibody

ABD7751 100 ug
EUR 525.6

CD134 Antibody

abx140447-100g 100 µg
EUR 400

CD134 Antibody

abx140447-100tests 100 tests
EUR 577.2

CD134 Antibody

abx140448-100g 100 µg
EUR 350

CD134 Antibody

abx140448-100tests 100 tests
EUR 510

CD134 Antibody

GWB-96FE7E 0.1 mg Ask for price

CD134 Antibody

GWB-687738 0.1 mg Ask for price

CD134 Antibody

E10-31362 100ul
EUR 225
Description: Available in various conjugation types.

CD134 Antibody

E10-31363 100ul
EUR 225
Description: Available in various conjugation types.

CD134 Antibody

E38PA4280 100ul
EUR 225
Description: Available in various conjugation types.

CD134 Antibody

E19-7751-1 50ug/50ul
EUR 145
Description: Available in various conjugation types.

CD134 Antibody

E19-7751-2 100ug/100ul
EUR 225
Description: Available in various conjugation types.

CD134 Antibody

MBS9608328-01mL 0.1mL
EUR 260

CD134 Antibody

MBS9608328-02mL 0.2mL
EUR 305

CD134 Antibody

MBS9608328-5x02mL 5x0.2mL
EUR 1220

CD134 Antibody

MBS8582420-01mL 0.1mL
EUR 305

CD134 Antibody

MBS8582420-01mLAF405L 0.1mL(AF405L)
EUR 465

CD134 Antibody

MBS8582420-01mLAF405S 0.1mL(AF405S)
EUR 465

CD134 Antibody

MBS8582420-01mLAF610 0.1mL(AF610)
EUR 465

CD134 Antibody

MBS8582420-01mLAF635 0.1mL(AF635)
EUR 465

CD134 Antibody

MBS8517125-005mg 0.05mg
EUR 235

CD134 Antibody

MBS8517125-01mg 0.1mg
EUR 305

CD134 Antibody

MBS8517125-01mLAF405M 0.1mL(AF405M)
EUR 465

CD134 Antibody

MBS8517125-01mLAF546 0.1mL(AF546)
EUR 465

CD134 Antibody

MBS8517125-01mLAF750 0.1mL(AF750)
EUR 465

OX-40/CD134

MBS370316-INQUIRE INQUIRE Ask for price

CD134 (OX40) (PE)

MBS6251432-01mL 0.1(mL
EUR 995

CD134 (OX40) (PE)

MBS6251432-5x01mL 5x0.1mL
EUR 4325

CD134 (OX40) (AP)

MBS6247471-01mL 0.1(mL
EUR 995

CD134 (OX40) (AP)

MBS6247471-5x01mL 5x0.1mL
EUR 4325

CD134 (OX40) (HRP)

MBS6250411-01mL 0.1(mL
EUR 995

CD134 (OX40) (HRP)

MBS6250411-5x01mL 5x0.1mL
EUR 4325

CD134 (OX40) (APC)

MBS6268329-01mL 0.1mL
EUR 995

CD134 (OX40) (APC)

MBS6268329-5x01mL 5x0.1mL
EUR 4325

CD134 (OX40) (FITC)

MBS6249499-01mL 0.1(mL
EUR 995

CD134 (OX40) (FITC)

MBS6249499-5x01mL 5x0.1mL
EUR 4325

CD134 Rabbit pAb

A24523 20μL
EUR 152.33

CD134 Rabbit mAb

56422 100ul
EUR 339

CD134 Rabbit mAb

E38A1018 100ug/100ul
EUR 255

CD134 Rabbit pAb

E47R2685 100ul
EUR 295

CD134, Mouse (OX40)

MBS4381531-002mgWithBSAAzideat02mgmL 0.02mg(WithBSA&Azideat0.2mg/mL)
EUR 230

CD134, Mouse (OX40)

MBS4381531-01mgWithBSAAzideat02mgmL 0.1mg(WithBSA&Azideat0.2mg/mL)
EUR 405

CD134, Mouse (OX40)

MBS4381531-01mgWithoutBSAAzideat1mgmL 0.1mg(WithoutBSA&Azideat1mg/mL)
EUR 405

CD134, Mouse (OX40)

MBS4381531-5x01mgWithBSAAzideat02mgmL 5x0.1mg(WithBSA&Azideat0.2mg/mL)
EUR 1725

CD134, Mouse (OX40)

MBS4381531-5x01mgWithoutBSAAzideat1mgmL 5x0.1mg(WithoutBSA&Azideat1mg/mL)
EUR 1725

CD134/OX40 ELISA

MBS495682-5x96Tests 5x96Tests
EUR 4655

CD134/OX40 ELISA

MBS495682-96Tests 96Tests
EUR 1005

CD134 Rabbit pAb

MBS8543698-01mL 0.1mL
EUR 305

CD134 Rabbit pAb

MBS8543698-01mLAF405L 0.1mL(AF405L)
EUR 565

CD134 Rabbit pAb

MBS8543698-01mLAF405S 0.1mL(AF405S)
EUR 565

CD134 Rabbit pAb

MBS8543698-01mLAF610 0.1mL(AF610)
EUR 565

CD134 Rabbit pAb

MBS8543698-01mLAF635 0.1mL(AF635)
EUR 565

CD134 Antibody (PE)

abx229303-100g 100 µg
EUR 162.5

CD134 Antibody (PE)

GWB-51D857 100 TESTS Ask for price

CD134 (OX40) (Biotin)

MBS6248503-01mL 0.1(mL
EUR 995

CD134 (OX40) (Biotin)

MBS6248503-5x01mL 5x0.1mL
EUR 4325

CD134 (OX40)(Biotin)

MBS6507234-005mg 0.05mg
EUR 1005

CD134 (OX40)(Biotin)

MBS6507234-5x005mg 5x0.05mg
EUR 4375

CD134 Antibody (APC)

abx229304-100g 100 µg
EUR 100

Rat CD134 Antibody

GWB-E27EEF 0.1 mg Ask for price

Cat CD134 Antibody

GWB-B3EA66 0.1 mg Ask for price

Rat CD134 Antibody

GWB-F24359 0.25 mg Ask for price

Cat CD134 Antibody

GWB-5A2C6C 0.25 mg Ask for price

OX40/CD134/TNFRSF4

MBS556150-01mL 0.1mL
EUR 455

OX40/CD134/TNFRSF4

MBS556150-5x01mL 5x0.1mL
EUR 1895

OX40/CD134/TNFRSF4

MO47051 100 ul
EUR 278.1

CD134 Antibody (FITC)

20-abx200691
  • Ask for price
  • Ask for price
  • 25 ug
  • 100 ug

CD134 Antibody (FITC)

abx229302-100g 100 µg
EUR 100

CD134 Antibody (FITC)

GWB-5DD6A2 0.1 mg Ask for price

CD134/OX40 Antibody

E8EM1701-24 100ul
EUR 275
Description: Available in various conjugation types.

CD134/OX40 Antibody

E8EM1701-25 100ul
EUR 275
Description: Available in various conjugation types.

Mouse CD134 Antibody

GWB-ED2B06 0.02 mg Ask for price

Mouse CD134 Antibody

GWB-7FFB78 0.1 mg Ask for price

Mouse CD134 Antibody

GWB-838D6E 0.25 mg Ask for price

CD134 Antibody (Biotin)

20-abx200689
  • Ask for price
  • Ask for price
  • 25 ug
  • 100 ug

CD134 Antibody (Biotin)

GWB-93423D 0.1 mg Ask for price

CD134 Blocking Peptide

20-abx161491
  • Ask for price
  • Ask for price
  • 1 mg
  • 5 mg

CD134 Blocking Peptide

20-abx161492
  • Ask for price
  • Ask for price
  • 1 mg
  • 5 mg

TNFRSF4/CD134 Antibody

DF7751 200ul
EUR 420

TNFRSF4/CD134 Antibody

DF7751-100ul 100ul
EUR 168
Description: WB,IHC,ELISA(peptide)

TNFRSF4/CD134 Antibody

DF7751-200ul 200ul
EUR 210
Description: WB,IHC,ELISA(peptide)

CD134 Blocking Peptide

DF7751-BP 1mg
EUR 234

TNFRSF4/CD134 Antibody

DF7812 200ul
EUR 420

TNFRSF4/CD134 Antibody

DF7812-100ul 100ul
EUR 168
Description: WB,ELISA(peptide)

TNFRSF4/CD134 Antibody

DF7812-200ul 200ul
EUR 210
Description: WB,ELISA(peptide)

CD134 Blocking Peptide

MBS8240078-1mg 1mg
EUR 190

CD134 Blocking Peptide

MBS8240078-5mg 5mg
EUR 345

CD134 Blocking Peptide

MBS8240078-5x5mg 5x5mg
EUR 1465

CD134 Blocking Peptide

MBS8204460-1mg 1mg
EUR 190

CD134 Blocking Peptide

MBS8204460-5mg 5mg
EUR 345

CD134 Blocking Peptide

MBS8204460-5x5mg 5x5mg
EUR 1465

CD134 Recombinant Protein

96-571 0.1 mg
EUR 619.8
Description: Tumor necrosis factor receptor superfamily member 4 (TNFRSF4) is also known as ACT35 antigen, OX40L receptor, TAX transcriptionally-activated glycoprotein 1 receptor, CD antigen CD134, OX40. OX40 / TNFRSF4 contains four TNFR-Cys repeats. TNFRSF4 is receptor for TNFSF4 / OX40L / GP34 and can interacts with TRAF2, TRAF3 and TRAF5.

CD134 Recombinant Protein

96-572 0.1 mg
EUR 619.8
Description: Tumor necrosis factor receptor superfamily member 4 (TNFRSF4) is also known as ACT35 antigen, OX40L receptor, TAX transcriptionally-activated glycoprotein 1 receptor, CD antigen CD134, OX40. OX40 / TNFRSF4 contains four TNFR-Cys repeats. TNFRSF4 is receptor for TNFSF4 / OX40L / GP34 and can interacts with TRAF2, TRAF3 and TRAF5.

Anti-Hu CD134 PE

1P-152-T025 25 tests
EUR 121

Anti-Hu CD134 PE

1P-152-T100 100 tests
EUR 242

Anti-Hu CD134 PE

MBS1800416-100Tests 100Tests
EUR 345

Anti-Hu CD134 PE

MBS1800416-5x100Tests 5x100Tests
EUR 1300

Anti-Hu CD134 APC

1A-152-T100 100 tests
EUR 242

Anti-Hu CD134 APC

MBS1800414-100Tests 100Tests
EUR 345

Anti-Hu CD134 APC

MBS1800414-5x100Tests 5x100Tests
EUR 1300

OX40 (CD134), Fc fusion

71175 100 µg
EUR 320
Description: Human secreted OX40, Fc fusion protein,_x000D_also known as Tumor Necrosis Factor_x000D_Receptor Superfamily Member 4,_x000D_TNFRSF4, and CD134, GenBank_x000D_Accession No. NM_003327, a.a. 29-216_x000D_expressed in a HEK293 cell expression_x000D_system. MW = 46.8 kDa (monomer). This_x000D_protein runs at a higher MW by SDS-PAGE_x000D_due to glycosylation.

Anti-Hu CD134 FITC

1F-152-T100 100 tests
EUR 198

Anti-Hu CD134 FITC

MBS1800415-100Tests 100Tests
EUR 305

Anti-Hu CD134 FITC

MBS1800415-5x100Tests 5x100Tests
EUR 1120

MOUSE ANTI RAT CD134

MBS213135-01mg 0.1mg
EUR 365

MOUSE ANTI RAT CD134

MBS213135-5x01mg 5x0.1mg
EUR 1465

MOUSE ANTI CAT CD134

MBS212886-01mg 0.1mg
EUR 390

MOUSE ANTI CAT CD134

MBS212886-5x01mg 5x0.1mg
EUR 1570

RAT ANTI MOUSE CD134

MBS212139-025mg 0.25mg
EUR 500

RAT ANTI MOUSE CD134

MBS212139-5x025mg 5x0.25mg
EUR 2070

RAT ANTI MOUSE CD134

MBS212140-01mg 0.1mg
EUR 355

RAT ANTI MOUSE CD134

MBS212140-5x01mg 5x0.1mg
EUR 1425

CD134/OX40 Rabbit pAb

A3646 50μL
EUR 173.58

CD134/OX40 Rabbit pAb

A7499 500μL
EUR 70.85

Mouse CD134 ELISA Kit

MBS824768-5x96Tests 5x96Tests
EUR 2880

Mouse CD134 ELISA Kit

MBS824768-96Tests 96Tests
EUR 645

Human CD134 ELISA Kit

MBS824604-5x96Tests 5x96Tests
EUR 2880

Human CD134 ELISA Kit

MBS824604-96Tests 96Tests
EUR 645

Mouse Anti Human CD134

MBS225745-01mg 0.1mg
EUR 400

Mouse Anti Human CD134

MBS225745-5x01mg 5x0.1mg
EUR 1630

CD134 (OX40) (MaxLight 405)

MBS6252376-01mL 0.1(mL
EUR 995

CD134 (OX40) (MaxLight 405)

MBS6252376-5x01mL 5x0.1mL
EUR 4325

CD134 (OX40) (MaxLight 550)

MBS6254456-01mL 0.1(mL
EUR 995

CD134 (OX40) (MaxLight 550)

MBS6254456-5x01mL 5x0.1mL
EUR 4325

CD134 (OX40) (MaxLight 490)

MBS6253416-01mL 0.1(mL
EUR 995

CD134 (OX40) (MaxLight 490)

MBS6253416-5x01mL 5x0.1mL
EUR 4325

CD134 (OX40) (MaxLight 650)

MBS6255496-01mL 0.1(mL
EUR 995

CD134 (OX40) (MaxLight 650)

MBS6255496-5x01mL 5x0.1mL
EUR 4325

CD134 (OX40) (MaxLight 750)

MBS6256536-01mL 0.1(mL
EUR 995

CD134 (OX40) (MaxLight 750)

MBS6256536-5x01mL 5x0.1mL
EUR 4325

Rat CD134 Antibody (FITC)

GWB-F26EE0 0.1 mg Ask for price

Cat CD134 Antibody (FITC)

GWB-CF8681 0.1 mg Ask for price

Anti-Hu CD134 Purified

11-152-C025 0.025 mg
EUR 71.5

Anti-Hu CD134 Purified

11-152-C100 0.1 mg
EUR 143

Mouse CD134 Antibody (RPE)

GWB-61D9E3 25 TESTS Ask for price

Mouse CD134 Antibody (RPE)

GWB-27E029 100 TESTS Ask for price

anti- CD134/OX40 antibody

FNab01422 100µg
EUR 702
Description: Antibody raised against CD134/OX40

Anti-Hu CD134 Purified

MBS1800413-01mg 0.1mg
EUR 260

Anti-Hu CD134 Purified

MBS1800413-5x01mg 5x0.1mg
EUR 930

CD134(OX40)-muIg-Biotin

MBS666822-0025mg 0.025mg
EUR 685

CD134(OX40)-muIg-Biotin

MBS666822-5x0025mg 5x0.025mg
EUR 2935

Mouse CD134 Antibody (FITC)

GWB-B38127 0.025 mg Ask for price

Mouse CD134 Antibody (FITC)

GWB-C19CD6 0.05 mg Ask for price

Rat CD134 Antibody (Biotin)

GWB-36B1A3 0.1 mg Ask for price

Mouse CD134 Antibody (FITC)

GWB-22A35F 0.1 mg Ask for price

Mouse CD134 Antibody (FITC)

GWB-23B953 0.5 mg Ask for price

Mouse CD134 Antibody (Biotin)

GWB-5E597C 0.025 mg Ask for price

Mouse CD134 Antibody (Biotin)

GWB-85C4D8 0.1 mg Ask for price

CD134 Recombinant Rabbit mAb

BS49211 50 ul
EUR 398
Description: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

CD134 Recombinant Rabbit mAb

BS46791 50 ul
EUR 398
Description: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

CD134 Rat monoclonal antibody

MB65857 50ul
EUR 275
Description: Rat IgG1 kappa. Liquid in PBS, pH 7.3, and 0.02% sodium azide.

CD134/OX40L Receptor Antibody

MBS5401010-01mg 0.1mg
EUR 445

CD134/OX40L Receptor Antibody

MBS5401010-5x01mg 5x0.1mg
EUR 1855

CD134 Antibody HRP Conjugated

MBS9461146-01mL 0.1mL
EUR 595

CD134 Antibody HRP Conjugated

MBS9461146-5x01mL 5x0.1mL
EUR 2525

CD134 [OX40] Recombinant Protein

90-407 50 ug
EUR 619.8
Description: CD134 (OX40) is a T cell activation antigen structurally belonging to a lymphocyte-specific subgroup of the nerve growth factor and tumor necrosis factor receptor superfamily, which also includes the T cell antigen CD27, B cell antigen CD40, FAS antigen and the T cell activation antigen 4-1BB. The human CD134 protein is expressed only on activated CD4 + T blasts, and its ligand has been identified as gp34. Interactions between CD134 and its ligand in vivo are necessary for the differentiation of activated B cells into highly immunoglobulin-producing cells, however not involved in other pathways of antigen-driven differentiation of B cells such as development of memory cells in the germinal centers. In addition, the CD134 and gp34 system directly mediate adhesion of activated T cells to vascular endothelial cells, and contribute to growth stimulation of the virus-infected T cells.
The lipid classification scheme is chemically based mostly and pushed by the distinct hydrophobic and hydrophilic components that compose the lipid. This structured vocabulary will facilitate the systematization of lipid biology and allow the cataloging of lipids and their properties in a means that’s appropriate with different macromolecular informationbases.

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