Reduced TREM2 activation in microglia of patients with Alzheimer's disease

Reduced TREM2 activation in microglia of patients with…

Loss-of-function variants of triggering receptor expressed on myeloid cells 2 (TREM2) enhance the chance of creating Alzheimer's illness (AD). The mechanism via which TREM2 contributes to the illness (TREM2 activation vs inactivation) is basically unknown. Right here, we…