Integration of chemical-genetic and genetic interaction data links bioactive compounds to cellular target pathways.

Bioactive compounds might be helpful analysis instruments and drug leads, however it’s usually tough to establish their mechanism of motion or mobile goal. Right here we examine the potential for integration of chemical-genetic and genetic interplay information to disclose details about the pathways and targets of inhibitory compounds.
Making the most of the present full set of yeast haploid deletion mutants, we generated drug-hypersensitivity (chemical-genetic) profiles for 12 compounds. Along with a set of compound-specific interactions, the chemical-genetic profiles recognized a big group of genes required for multidrug resistance. Specifically, yeast mutants missing a practical vacuolar H(+)-ATPase present multidrug sensitivity, a phenomenon that could be conserved in mammalian cells.
By filtering chemical-genetic profiles for the multidrug-resistant genes after which clustering the compound-specific profiles with a compendium of large-scale genetic interplay profiles, we have been in a position to establish goal pathways or proteins. This technique thus gives a strong means for inferring mechanism of motion.

Sign transduction by focal adhesion kinase in most cancers.

Mobile interactions with furthermobile matrix play important roles in tumor initiation, development and metastasis. Focal adhesion kinase (FAK) is a cytoplasmic tyrosine kinase recognized as a key mediator of signaling by integrins, a significant household of cell floor receptors for furthermobile matrix, in addition to different receptors in each regular and most cancers cells.
FAK is activated by integrins by way of disruption of an auto-inhibitory intra-molecular interplay between its kinase area and the amino terminal FERM area. The activated FAK kinds a binary complicated with Src household kinases which might phosphorylate different substrates and set off a number of intramobile signaling pathways to control varied mobile features. Submobile localization of FAK in focal adhesions is important for FAK signaling, which is one other distinguishing function of the kinase.
Integrin-FAK signaling has been proven to activate a lot of signaling pathways by way of phosphorylation and protein-protein interactions to advertise tumorigenesis. FAK additionally performs a outstanding position in tumor development and metastasis by way of its regulation of each most cancers cells and their microenvironments together with most cancers cell migration, invasion, epithelial to mesenchymal transition, and angiogenesis.
Extra just lately, a task for FAK in tumor initiation and development has been demonstrated instantly utilizing xenograft in addition to conditional knockout mouse fashions. In settlement with these experimental information, overexpression and activation of FAK have been present in a wide range of human cancers.
Quite a lot of small molecule inhibitors for FAK have been developed and in varied phases of testing for most cancers therapies. General, the intensive analysis on FAK signaling in most cancers have yielded a wealth of knowledge on this pivotal kinase and these and future research are resulting in probably novel therapies for most cancers.

Neuroplasticity subserving motor ability studying.

Latest years have seen vital progress in our understanding of the neural substrates of motor ability studying. Advances in neuroimaging present new perception into practical reorganization related to the acquisition, consolidation, and retention of motor abilities.
Plastic adjustments involving structural reorganization in grey and white matter structure that happen over shorter time durations than beforehand thought have been documented as properly. Knowledge from experimental animals supplied essential info on believable mobile and molecular substrates contributing to mind reorganization underlying ability acquisition in people. Right here, we overview findings demonstrating practical and structural plasticity throughout totally different spatial and temporal scales that mediate motor ability studying whereas figuring out converging areas of curiosity and attainable avenues for future analysis.
Integration of chemical-genetic and genetic interaction data links bioactive compounds to cellular target pathways.

Endotyping bronchial asthma: new insights into key pathogenic mechanisms in a fancy, heterogeneous illness.

Scientific bronchial asthma could be very extensively assumed to be the web results of extreme irritation pushed by aberrant T-helper-2 (Th2) immunity that results in infected, remodelled airways after which practical derangement that, in flip, causes signs.
This notion of illness is definitely poorly supported by information, and there are substantial discrepancies and really poor correlation between irritation, harm, practical impairment, and diploma of signs. Moreover, this drawback is compounded by the poor understanding of the heterogeneity of scientific illness. Failure to recognise and uncover the underlying mechanisms of those main variants or endotypes of bronchial asthma is, arguably, the key mental limitation to progress at current.
Luckily, each scientific analysis and animal fashions are very properly suited to dissecting the mobile and molecular foundation of illness endotypes. This method is already suggesting solely novel pathways to disease-eg, various macrophage specification, steroid refractory innate immunity, the interleukin-17-regulatory T-cell axis, epidermal progress issue receptor co-amplification, and Th2-mimicking however non-T-cell, interleukins 18 and 33 dependent processes that may supply sudden therapeutic alternatives for particular affected person endotypes.

Immunological elements of demyelinating illnesses.

Major demyelination within the central nervous system outcomes from harm to the myelin sheath or oligodendroglia and might be produced by a wide range of mechanisms, together with metabolic disturbances, toxicities, an infection, and autoimmunity. The main human demyelinating illness affecting the central nervous system is a number of sclerosis (MS).
Though the etiology of MS shouldn’t be recognized, present information point out that each genetic and environmental elements contribute to pathogenesis. Experimental allergic encephalomyelitis (EAE) is induced by immunization of genetically vulnerable animals with myelin proteins.
That is mediated by autoimmune T cells. Characterization of MHC restriction, high-quality specificity of antigen recognition, and T cell receptor (TCR) utilization by encephalitogenic T cells has resulted in extremely particular immunotherapies. Each HLA and TCR genes have been linked to susceptibility for MS which is extensively believed to be mediated by T cells that acknowledge an as but unidentified autoantigen.
Due to the advances within the understanding and therapy of EAE, current analysis in MS has been targeted on the characterization of mobile immune responses in opposition to myelin elements. The outcomes of those research are reviewed and the potential implications of those findings for the pathogenesis and future remedy of MS are examined.

Comparative proteomic evaluation of 11 frequent cell traces reveals ubiquitous however various expression of most proteins.

Deep proteomic evaluation of mammalian cell traces would yield a listing of the constructing blocks of essentially the most generally used techniques in organic analysis. Mass spectrometry-based proteomics can establish and quantify proteins in a worldwide and unbiased method and may spotlight the mobile processes which can be altered between such techniques.
We analyzed 11 human cell traces utilizing an LTQ-Orbitrap household mass spectrometer with a “excessive area” Orbitrap mass analyzer with improved decision and sequencing velocity. We recognized a complete of 11,731 proteins, and on common 10,361 ± 120 proteins in every cell line. This very excessive proteome protection enabled evaluation of a broad vary of processes and features.
Regardless of the distinct origins of the cell traces, our quantitative outcomes confirmed surprisingly excessive similarity by way of expressed proteins. Nonetheless, this international similarity of the proteomes didn’t suggest equal expression ranges of particular person proteins throughout the 11 cell traces, as we discovered vital variations in expression ranges for an estimated two-third of them.
The variability in mobile expression ranges was comparable for high and low abundance proteins, and even lots of the most extremely expressed proteins with family roles confirmed vital variations between cells. Metabolic pathways, which have excessive redundancy, exhibited variable expression, whereas primary mobile features such because the basal transcription equipment assorted a lot much less.

Human CD27 antigen(CD27) ELISA kit

E01C1473-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Human CD27 antigen(CD27) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat CD27 antigen(CD27) ELISA kit

E02C1473-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Rat CD27 antigen(CD27) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat CD27 antigen(CD27) ELISA kit

E02C1473-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Rat CD27 antigen(CD27) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat CD27 antigen(CD27) ELISA kit

E02C1473-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Rat CD27 antigen(CD27) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse CD27 antigen(CD27) ELISA kit

E03C1473-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Mouse CD27 antigen(CD27) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse CD27 antigen(CD27) ELISA kit

E03C1473-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Mouse CD27 antigen(CD27) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse CD27 antigen(CD27) ELISA kit

E03C1473-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Mouse CD27 antigen(CD27) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit CD27 antigen(CD27) ELISA kit

E04C1473-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Rabbit CD27 antigen(CD27) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit CD27 antigen(CD27) ELISA kit

E04C1473-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Rabbit CD27 antigen(CD27) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit CD27 antigen(CD27) ELISA kit

E04C1473-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Rabbit CD27 antigen(CD27) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat CD27 antigen(CD27) ELISA kit

E06C1473-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Goat CD27 antigen(CD27) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat CD27 antigen(CD27) ELISA kit

E06C1473-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Goat CD27 antigen(CD27) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat CD27 antigen(CD27) ELISA kit

E06C1473-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Goat CD27 antigen(CD27) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey CD27 antigen(CD27) ELISA kit

E09C1473-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Monkey CD27 antigen(CD27) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey CD27 antigen(CD27) ELISA kit

E09C1473-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Monkey CD27 antigen(CD27) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey CD27 antigen(CD27) ELISA kit

E09C1473-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Monkey CD27 antigen(CD27) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human CD27 antigen(CD27) ELISA kit

CSB-EL004910HU-24T 1 plate of 24 wells
EUR 165
Description: Quantitativesandwich ELISA kit for measuring Human CD27 antigen (CD27) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human CD27 antigen(CD27) ELISA kit

1-CSB-EL004910HU
  • EUR 703.00
  • EUR 4843.00
  • EUR 2570.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Human CD27 antigen(CD27) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Mouse CD27 antigen(CD27) ELISA kit

CSB-EL004910MO-24T 1 plate of 24 wells
EUR 165
Description: Quantitativesandwich ELISA kit for measuring Mouse CD27 antigen (CD27) in samples from serum, plasma, cell culture supernates, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Mouse CD27 antigen(CD27) ELISA kit

1-CSB-EL004910MO
  • EUR 703.00
  • EUR 4843.00
  • EUR 2570.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Mouse CD27 antigen(CD27) in samples from serum, plasma, cell culture supernates, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Mouse CD27 antigen, Cd27 ELISA KIT

ELI-33094m 96 Tests
EUR 865

Pig CD27 antigen(CD27) ELISA kit

E07C1473-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Porcine CD27 antigen(CD27) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig CD27 antigen(CD27) ELISA kit

E07C1473-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Porcine CD27 antigen(CD27) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig CD27 antigen(CD27) ELISA kit

E07C1473-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Porcine CD27 antigen(CD27) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog CD27 antigen(CD27) ELISA kit

E08C1473-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Canine CD27 antigen(CD27) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog CD27 antigen(CD27) ELISA kit

E08C1473-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Canine CD27 antigen(CD27) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog CD27 antigen(CD27) ELISA kit

E08C1473-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Canine CD27 antigen(CD27) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human CD27 Antigen (CD27) ELISA Kit

20-abx156729
  • EUR 7112.00
  • EUR 3792.00
  • EUR 879.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

CD27 antibody

70R-9668 50 ug
EUR 467
Description: Affinity purified rabbit polyclonal CD27 antibody

CD27 Antibody

ABD2296 100 ug
EUR 438

CD27 Antibody

ABD6709 100 ug
EUR 438

anti-CD27

YF-PA10777 50 ug
EUR 363
Description: Mouse polyclonal to CD27

anti-CD27

YF-PA10778 100 ug
EUR 403
Description: Rabbit polyclonal to CD27

CD27 antibody

70R-16264 50 ul
EUR 435
Description: Rabbit polyclonal CD27 antibody

CD27 antibody

10R-6372 100 ug
EUR 192
Description: Armenian Hamster monoclonal CD27 antibody

CD27 antibody

10R-6373 100 ug
EUR 224
Description: Armenian Hamster monoclonal CD27 antibody

CD27 antibody

10R-6374 100 ug
EUR 220
Description: Mouse monoclonal CD27 antibody

CD27 antibody

10R-7982 100 ug
EUR 489
Description: Armenian Hamster monoclonal CD27 antibody

CD27 antibody

10R-7983 100 ug
EUR 489
Description: American Hamster monoclonal CD27 antibody

CD27 Antibody

DF6709 200ul
EUR 304
Description: CD27 Antibody detects endogenous levels of total CD27.

CD27 Antibody

DF2296 200ul
EUR 304
Description: CD27 antibody detects endogenous levels of total CD27.

CD27 Antibody

1-CSB-PA004910GA01HU
  • EUR 597.00
  • EUR 333.00
  • 150ul
  • 50ul
Description: A polyclonal antibody against CD27. Recognizes CD27 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB

CD27 Antibody

1-CSB-PA08235A0Rb
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against CD27. Recognizes CD27 from Human, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:500-1:1000, IF:1:50-1:500

pENTR223-CD27

PVT12720 2 ug
EUR 391

CD27 Antibody

1-CSB-PA123791
  • EUR 317.00
  • EUR 244.00
  • 100ul
  • 50ul
Description: A polyclonal antibody against CD27. Recognizes CD27 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:50-1:200

CD27 Antibody

1-CSB-PA149291
  • EUR 317.00
  • EUR 244.00
  • 100ul
  • 50ul
Description: A polyclonal antibody against CD27. Recognizes CD27 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;ELISA:1:2000-1:5000, WB:1:1000-1:5000, IHC:1:50-1:200

CD27 siRNA

20-abx910982
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol

CD27 siRNA

20-abx910983
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol

CD27 Antibody

32512-100ul 100ul
EUR 252

CD27 Antibody

49854-100ul 100ul
EUR 333

CD27 Antibody

49854-50ul 50ul
EUR 239

Recombinant Cynomolgus CD27 molecule/CD27(C-6His)

C960-10ug 10ug
EUR 156
Description: Lyophilized from a 0.2 μm filtered solution of 20mMTris,150mM NaCl,pH8.5.

Recombinant Cynomolgus CD27 molecule/CD27(C-6His)

C960-1mg 1mg
EUR 2283
Description: Lyophilized from a 0.2 μm filtered solution of 20mMTris,150mM NaCl,pH8.5.

Recombinant Cynomolgus CD27 molecule/CD27(C-6His)

C960-500ug 500ug
EUR 1613
Description: Lyophilized from a 0.2 μm filtered solution of 20mMTris,150mM NaCl,pH8.5.

Recombinant Cynomolgus CD27 molecule/CD27(C-6His)

C960-50ug 50ug
EUR 369
Description: Lyophilized from a 0.2 μm filtered solution of 20mMTris,150mM NaCl,pH8.5.

Recombinant Cynomolgus CD27 molecule/CD27(C-6His)

CA62-10ug 10ug
EUR 202
Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.

Recombinant Cynomolgus CD27 molecule/CD27(C-6His)

CA62-1mg 1mg
EUR 2486
Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.

Recombinant Cynomolgus CD27 molecule/CD27(C-6His)

CA62-500ug 500ug
EUR 1613
Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.

Recombinant Cynomolgus CD27 molecule/CD27(C-6His)

CA62-50ug 50ug
EUR 496
Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.

Guinea pig CD27 antigen(CD27) ELISA kit

E05C1473-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Guinea pig CD27 antigen(CD27) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig CD27 antigen(CD27) ELISA kit

E05C1473-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Guinea pig CD27 antigen(CD27) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig CD27 antigen(CD27) ELISA kit

E05C1473-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Guinea pig CD27 antigen(CD27) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

T-cell Activation Antigen CD27 (CD27) Antibody

20-abx111471
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

T-cell Activation Antigen CD27 (CD27) Antibody

20-abx306428
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

T-cell Activation Antigen CD27 (CD27) Antibody

abx414870-025mg 0.25 mg
EUR 565

T-cell Activation Antigen CD27 (CD27) Antibody

abx415298-01mg 0.1 mg
EUR 453

T-cell Activation Antigen CD27 (CD27) Antibody

abx415489-01mg 0.1 mg
EUR 439

T-cell Activation Antigen CD27 (CD27) Antibody

abx415492-1mg 1 mg
EUR 829

T-cell Activation Antigen CD27 (CD27) Antibody

abx432467-200ul 200 ul
EUR 384

T-cell Activation Antigen CD27 (CD27) Protein

20-abx260944
  • EUR 3418.00
  • EUR 328.00
  • EUR 230.00
  • 1 mg
  • 20 ug
  • 5 ug

T-cell Activation Antigen CD27 (CD27) Antibody

20-abx211067
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul

T-cell Activation Antigen CD27 (CD27) Antibody

20-abx211217
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul

T-cell Activation Antigen CD27 (CD27) Antibody

20-abx225088
  • EUR 370.00
  • EUR 606.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 50 ul

T-cell Activation Antigen CD27 (CD27) Antibody

abx231453-100ug 100 ug
EUR 481

T-cell Activation Antigen CD27 (CD27) Antibody

20-abx001588
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

T-cell Activation Antigen CD27 (CD27) Antibody

abx146709-100ug 100 ug
EUR 439

T-cell Activation Antigen CD27 (CD27) Antibody

abx147085-100ug 100 ug
EUR 439

T-cell Activation Antigen CD27 (CD27) Antibody

abx139209-01mg 0.1 mg
EUR 356

T-cell Activation Antigen CD27 (CD27) Antibody

abx027573-400ul 400 ul
EUR 523

T-cell Activation Antigen CD27 (CD27) Antibody

abx027573-80l 80 µl
EUR 286

T-cell Activation Antigen CD27 (CD27) Antibody (HRP)

20-abx306429
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

T-cell Activation Antigen CD27 (CD27) Antibody (FITC)

20-abx306430
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

T-cell Activation Antigen CD27 (CD27) Antibody (Biotin)

20-abx306431
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

T-cell Activation Antigen CD27 (CD27) Antibody (Biotin)

abx414871-01mg 0.1 mg
EUR 509

T-cell Activation Antigen CD27 (CD27) Antibody (FITC)

abx414872-01mg 0.1 mg
EUR 509

T-cell Activation Antigen CD27 (CD27) Antibody (RPE)

abx414873-01mg 0.1 mg
EUR 592

T-cell Activation Antigen CD27 (CD27) Antibody (APC)

abx415296-100tests 100 tests
EUR 718

T-cell Activation Antigen CD27 (CD27) Antibody (FITC)

abx415297-01mg 0.1 mg
EUR 648

T-cell Activation Antigen CD27 (CD27) Antibody (RPE)

abx415299-100tests 100 tests
EUR 718

T-cell Activation Antigen CD27 (CD27) Antibody (FITC)

abx415488-01mg 0.1 mg
EUR 509

T-cell Activation Antigen CD27 (CD27) Antibody (RPE)

abx415490-100tests 100 tests
EUR 592

T-cell Activation Antigen CD27 (CD27) Antibody (RPE)

abx415491-25tests025ml 25 tests (0.25 ml)
EUR 314

T-cell Activation Antigen CD27 (CD27) Antibody (FITC)

abx200208-100tests 100 tests
EUR 425

T-cell Activation Antigen CD27 (CD27) Antibody (PE)

abx200209-100tests 100 tests
EUR 495

T-cell Activation Antigen CD27 (CD27) Antibody (APC)

abx200210-100tests 100 tests
EUR 718

T-cell Activation Antigen CD27 (CD27) Antibody (PE)

abx139211-100tests 100 tests
EUR 481

T-cell Activation Antigen CD27 (CD27) Antibody (APC)

abx139212-100tests 100 tests
EUR 481

T-cell Activation Antigen CD27 (CD27) Antibody (FITC)

abx139213-100tests 100 tests
EUR 425

CD27 Polyclonal Antibody

A1074-100
EUR 218

CD27 Blocking Peptide

33R-5024 100 ug
EUR 180
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of CD27 antibody, catalog no. 70R-9668

CD27 antibody (FITC)

61R-1068 100 ug
EUR 208
Description: Armenian Hamster monoclonal CD27 antibody (FITC)

CD27 antibody (PE)

61R-1230 100 ug
EUR 316
Description: Armenian Hamster monoclonal CD27 antibody (PE)

CD27 antibody (biotin)

61R-1486 100 ug
EUR 219
Description: Armenian Hamster monoclonal CD27 antibody (biotin)

CD27 antibody (biotin)

61R-1487 100 ug
EUR 316
Description: Mouse monoclonal CD27 antibody (biotin)

CD27 antibody (allophycocyanin)

61R-1716 100 ug
EUR 478
Description: Armenian Hamster monoclonal CD27 antibody (allophycocyanin)

CD27 Blocking Peptide

DF6709-BP 1mg
EUR 195

CD27 Blocking Peptide

DF2296-BP 1mg
EUR 195

Anti-CD27 antibody

PAab01453 100 ug
EUR 355

CD27 cloning plasmid

CSB-CL004910HU-10ug 10ug
EUR 233
Description: A cloning plasmid for the CD27 gene.

CD27 Polyclonal Antibody

ABP58051-003ml 0.03ml
EUR 158
Description: A polyclonal antibody for detection of CD27 from Human. This CD27 antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human CD27 protein at amino acid sequence of 1-80

CD27 Polyclonal Antibody

ABP58051-01ml 0.1ml
EUR 289
Description: A polyclonal antibody for detection of CD27 from Human. This CD27 antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human CD27 protein at amino acid sequence of 1-80

CD27 Polyclonal Antibody

ABP58051-02ml 0.2ml
EUR 414
Description: A polyclonal antibody for detection of CD27 from Human. This CD27 antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human CD27 protein at amino acid sequence of 1-80

CD27(203.6) Antibody

BNC040163-100 100uL
EUR 199
Description: Primary antibody against CD27(203.6), CF405S conjugate, Concentration: 0.1mg/mL

CD27(203.6) Antibody

BNC040163-500 500uL
EUR 544
Description: Primary antibody against CD27(203.6), CF405S conjugate, Concentration: 0.1mg/mL

CD27(203.6) Antibody

BNC430163-100 100uL
EUR 199
Description: Primary antibody against CD27(203.6), CF543 conjugate, Concentration: 0.1mg/mL

CD27(203.6) Antibody

BNC430163-500 500uL
EUR 544
Description: Primary antibody against CD27(203.6), CF543 conjugate, Concentration: 0.1mg/mL

CD27(203.6) Antibody

BNCH0163-100 100uL
EUR 199
Description: Primary antibody against CD27(203.6), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

CD27(203.6) Antibody

BNCH0163-500 500uL
EUR 544
Description: Primary antibody against CD27(203.6), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

CD27(203.6) Antibody

BNC610163-100 100uL
EUR 199
Description: Primary antibody against CD27(203.6), CF660R conjugate, Concentration: 0.1mg/mL

CD27(203.6) Antibody

BNC610163-500 500uL
EUR 544
Description: Primary antibody against CD27(203.6), CF660R conjugate, Concentration: 0.1mg/mL

CD27(203.6) Antibody

BNC800163-100 100uL
EUR 199
Description: Primary antibody against CD27(203.6), CF680 conjugate, Concentration: 0.1mg/mL

CD27(203.6) Antibody

BNC800163-500 500uL
EUR 544
Description: Primary antibody against CD27(203.6), CF680 conjugate, Concentration: 0.1mg/mL

CD27(203.6) Antibody

BNC470163-100 100uL
EUR 199
Description: Primary antibody against CD27(203.6), CF647 conjugate, Concentration: 0.1mg/mL

CD27(203.6) Antibody

BNC470163-500 500uL
EUR 544
Description: Primary antibody against CD27(203.6), CF647 conjugate, Concentration: 0.1mg/mL

CD27(203.6) Antibody

BNC550163-100 100uL
EUR 199
Description: Primary antibody against CD27(203.6), CF555 conjugate, Concentration: 0.1mg/mL

CD27(203.6) Antibody

BNC550163-500 500uL
EUR 544
Description: Primary antibody against CD27(203.6), CF555 conjugate, Concentration: 0.1mg/mL

CD27(203.6) Antibody

BNCB0163-100 100uL
EUR 199
Description: Primary antibody against CD27(203.6), Biotin conjugate, Concentration: 0.1mg/mL

CD27(203.6) Antibody

BNCB0163-500 500uL
EUR 544
Description: Primary antibody against CD27(203.6), Biotin conjugate, Concentration: 0.1mg/mL

CD27(203.6) Antibody

BNC810163-100 100uL
EUR 199
Description: Primary antibody against CD27(203.6), CF680R conjugate, Concentration: 0.1mg/mL

CD27(203.6) Antibody

BNC810163-500 500uL
EUR 544
Description: Primary antibody against CD27(203.6), CF680R conjugate, Concentration: 0.1mg/mL

CD27(203.6) Antibody

BNC700163-100 100uL
EUR 199
Description: Primary antibody against CD27(203.6), CF770 conjugate, Concentration: 0.1mg/mL

CD27(203.6) Antibody

BNC700163-500 500uL
EUR 544
Description: Primary antibody against CD27(203.6), CF770 conjugate, Concentration: 0.1mg/mL

CD27(203.6) Antibody

BNC880163-100 100uL
EUR 199
Description: Primary antibody against CD27(203.6), CF488A conjugate, Concentration: 0.1mg/mL

CD27(203.6) Antibody

BNC880163-500 500uL
EUR 544
Description: Primary antibody against CD27(203.6), CF488A conjugate, Concentration: 0.1mg/mL

CD27(203.6) Antibody

BNC940163-100 100uL
EUR 199
Description: Primary antibody against CD27(203.6), CF594 conjugate, Concentration: 0.1mg/mL

CD27(203.6) Antibody

BNC940163-500 500uL
EUR 544
Description: Primary antibody against CD27(203.6), CF594 conjugate, Concentration: 0.1mg/mL

CD27(203.6) Antibody

BNC680163-100 100uL
EUR 199
Description: Primary antibody against CD27(203.6), CF568 conjugate, Concentration: 0.1mg/mL

CD27(203.6) Antibody

BNC680163-500 500uL
EUR 544
Description: Primary antibody against CD27(203.6), CF568 conjugate, Concentration: 0.1mg/mL

CD27(203.6) Antibody

BNCA0163-250 250uL
EUR 383
Description: Primary antibody against CD27(203.6), APC conjugate, Concentration: 0.1mg/mL

CD27(203.6) Antibody

BNCAP0163-100 100uL
EUR 199
Description: Primary antibody against CD27(203.6), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

CD27(203.6) Antibody

BNCAP0163-500 500uL
EUR 544
Description: Primary antibody against CD27(203.6), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

CD27(203.6) Antibody

BNUM0163-50 50uL
EUR 395
Description: Primary antibody against CD27(203.6), 1mg/mL

CD27(203.6) Antibody

BNCP0163-250 250uL
EUR 383
Description: Primary antibody against CD27(203.6), PerCP conjugate, Concentration: 0.1mg/mL

CD27(203.6) Antibody

BNC050163-100 100uL
EUR 199
Description: Primary antibody against CD27(203.6), CF405M conjugate, Concentration: 0.1mg/mL

CD27(203.6) Antibody

BNC050163-500 500uL
EUR 544
Description: Primary antibody against CD27(203.6), CF405M conjugate, Concentration: 0.1mg/mL

CD27(203.6) Antibody

BNC400163-100 100uL
EUR 199
Description: Primary antibody against CD27(203.6), CF640R conjugate, Concentration: 0.1mg/mL

CD27(203.6) Antibody

BNC400163-500 500uL
EUR 544
Description: Primary antibody against CD27(203.6), CF640R conjugate, Concentration: 0.1mg/mL

CD27 Polyclonal Antibody

A50648 100 µg
EUR 570.55
Description: kits suitable for this type of research

CD27 Rabbit pAb

A1945-100ul 100 ul
EUR 308

CD27 Rabbit pAb

A1945-200ul 200 ul
EUR 459

CD27 Rabbit pAb

A1945-20ul 20 ul
EUR 183

CD27 Rabbit pAb

A1945-50ul 50 ul
EUR 223

CD27(203.6) Antibody

BNCR0163-250 250uL
EUR 383
Description: Primary antibody against CD27(203.6), RPE conjugate, Concentration: 0.1mg/mL

CD27(203.6) Antibody

BNUB0163-100 100uL
EUR 209
Description: Primary antibody against CD27(203.6), Concentration: 0.2mg/mL

CD27(203.6) Antibody

BNUB0163-500 500uL
EUR 458
Description: Primary antibody against CD27(203.6), Concentration: 0.2mg/mL

CD27 Rabbit pAb

A15654-100ul 100 ul
EUR 308

CD27 Rabbit pAb

A15654-200ul 200 ul
EUR 459

CD27 Rabbit pAb

A15654-20ul 20 ul
EUR 183

CD27 Rabbit pAb

A15654-50ul 50 ul
EUR 223

Human CD27 Antibody

32149-05111 150 ug
EUR 261

Anti-CD27 antibody

STJ118114 100 µl
EUR 277

Anti-CD27 antibody

STJ22984 100 µl
EUR 277
Description: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.

Anti-CD27 antibody

STJ16100092 100 µg
EUR 406

Anti-CD27 antibody

STJ16100093 100 tests
EUR 615

Anti-CD27 antibody

STJ16101136 100 µg
EUR 354

Anti-CD27 antibody

STJ191672 200 µl
EUR 197
Description: Unconjugated Rabbit polyclonal to CD27

Anti-CD27 Antibody

PB9931 100ug/vial
EUR 334

CD27 Polyclonal Antibody

ES10514-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against CD27 from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

CD27 Polyclonal Antibody

ES10514-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against CD27 from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

CD27 Conjugated Antibody

C49854 100ul
EUR 397

anti- CD27 antibody

FNab01453 100µg
EUR 505.25
Description: Antibody raised against CD27

CD27 Rabbit mAb

A11505 20 μL
EUR 15

T-cell Activation Antigen CD27 (CD27) Antibody (PerCP-Cy5.5)

abx200211-100tests 100 tests
EUR 481

T-cell Activation Antigen CD27 (CD27) Antibody (PE-DyLight 594)

abx139210-100tests 100 tests
EUR 523

CD27 protein (His tag)

80R-2462 20 ug
EUR 322
Description: Purified recombinant CD27 protein (His tag)

CD27 ELISA KIT|Human

EF008505 96 Tests
EUR 689

CD27 recombinant monoclonal antibody

A5851 100ul X 3
EUR 595
Description: A recombinant monoclonal antibody from rabbit against human CD27 for WB,ELISA

Anti-CD27 (1E2-A3)

YF-MA12321 100 ug
EUR 363
Description: Mouse monoclonal to CD27

Human CD27 ELISA kit

55R-2259 1 kit
EUR 860
Description: ELISA kit for detection of CD27 (TNFRSF7) in the research laboratory

CD27 Antibody, HRP conjugated

1-CSB-PA08235B0Rb
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against CD27. Recognizes CD27 from Human. This antibody is HRP conjugated. Tested in the following application: ELISA

CD27 Antibody, FITC conjugated

1-CSB-PA08235C0Rb
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against CD27. Recognizes CD27 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

CD27 Antibody, Biotin conjugated

1-CSB-PA08235D0Rb
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against CD27. Recognizes CD27 from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA

CD27 Recombinant Protein (Human)

RP006316 100 ug Ask for price

CD27 Recombinant Protein (Rat)

RP193904 100 ug Ask for price

CD27 Recombinant Protein (Mouse)

RP122483 100 ug Ask for price

CD27 Recombinant Protein (Mouse)

RP122486 100 ug Ask for price

Anti-Hu CD27 Purified

11-308-C025 0.025 mg
EUR 99

Anti-Hu CD27 Purified

11-308-C100 0.1 mg
EUR 158

Anti-Hu CD27 APC

1A-308-T025 25 tests
EUR 140

Anti-Hu CD27 APC

1A-308-T100 100 tests
EUR 240

Anti-Hu CD27 FITC

1F-308-T025 25 tests
EUR 122

Anti-Hu CD27 FITC

1F-308-T100 100 tests
EUR 204

Anti-Hu CD27 PE

1P-308-T025 25 tests
EUR 140

Anti-Hu CD27 PE

1P-308-T100 100 tests
EUR 240

Mouse CD27 shRNA Plasmid

20-abx973161
  • EUR 801.00
  • EUR 1121.00
  • 150 µg
  • 300 µg

Human CD27 shRNA Plasmid

20-abx950661
  • EUR 801.00
  • EUR 1121.00
  • 150 µg
  • 300 µg

CD27 Human Recombinant Protein

PROTP26842 Regular: 20ug
EUR 317
Description: CD27 Human Recombinant produced in E. coli is a single polypeptide chain containing 196 amino acids (21-191) and having a molecular mass of 21.8 kDa.;CD27 is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

CD27 / TNFRSF7 (Human) ELISA Kit

E4547-100
EUR 865

Anti-CD27 Antibody (LPFS2/1611)

A1483-100
EUR 479

Recombinant CD27 Binding Protein (CD27BP)

4-RPM233Hu01
  • EUR 503.20
  • EUR 238.00
  • EUR 1612.00
  • EUR 604.00
  • EUR 1108.00
  • EUR 400.00
  • EUR 3880.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human CD27 Binding Protein expressed in: E.coli
We harness data of those cell line proteomes for the development of a broad protection “super-SILAC” quantification commonplace. Along with the accompanying paper (Schaab, C. MCP 2012, PMID: 22301388) (17) these information can be utilized to acquire reference expression profiles for proteins of curiosity each inside and throughout cell line proteomes.

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