Fluorescence probes used for detection of reactive oxygen species.

Fluorescence probes used for detection of reactive oxygen species.

by
Endogenously produced pro-oxidant reactive species are important to life, being concerned in a number of organic features. Nevertheless, when overproduced (e.g. attributable to exogenous stimulation), or when the degrees of antioxidants grow to be severely depleted, these reactive species grow to be extremely dangerous, inflicting oxidative stress by the oxidation of biomolecules, resulting in mobile harm which will grow to be irreversible and trigger cell dying.
The scientific analysis within the subject of reactive oxygen species (ROS) related organic features and/or deleterious results is repeatedly requiring new delicate and particular instruments with a purpose to allow a deeper perception on its motion mechanisms.
Nevertheless, reactive species current some traits that make them troublesome to detect, specifically their very brief lifetime and the number of antioxidants present in vivo, able to capturing these reactive species. It’s, subsequently, important to develop methodologies able to overcoming this kind of obstacles.
Fluorescent probes are wonderful sensors of ROS attributable to their excessive sensitivity, simplicity in knowledge assortment, and excessive spatial decision in microscopic imaging methods. Therefore, the principle aim of the current paper is to evaluate the fluorescence methodologies which were used for detecting ROS in organic and non-biological media.

Normalization of gene expression measurements in tumor tissues: comparability of 13 endogenous management genes.

For interpretation of quantitative gene expression measurements in medical tumor samples, a normalizer is important to right expression knowledge for variations in mobile enter, RNA high quality, and RT effectivity between samples. In lots of research, a single housekeeping gene is used for normalization. Nevertheless, no unequivocal single reference gene (with confirmed invariable expression between cells) has been recognized but.
As the most effective various, the imply expression of a number of housekeeping genes can be utilized for normalization. On this research, no try was made to find out the gold-standard gene for normalization, however to determine the most effective single housekeeping gene that would precisely substitute the measurement of a number of genes.
Expression patterns of 13 steadily used housekeeping genes had been decided in 80 regular and tumor samples from colorectal, breast, prostate, pores and skin, and bladder tissues with real-time quantitative RT-PCR. These genes included, giant ribosomal protein, beta-actin, cyclophilin A, glyceraldehyde-3-phosphate dehydrogenase, phosphoglycerokinase 1, beta-2-microglobin, beta-glucuronidase, hypoxanthine ribosyltransferase (HPRT), TATA-box-binding protein, transferrin receptor, porphobilinogen deaminase, ATP synthase 6, and 18S ribosomal RNA.
Principal element evaluation was used to research these expression patterns, unbiased of the extent of expression. Our method recognized HPRT as the one greatest reference gene that could possibly be used as an correct and financial various for the measurement of a number of housekeeping genes. We advocate this gene for future research to standardize gene expression measurements in most cancers analysis and tumor diagnostics till a particular gold customary has been decided.

Mapping intact protein isoforms in discovery mode utilizing top-down proteomics.

A full description of the human proteome depends on the difficult process of detecting mature and altering types of protein molecules within the physique. Massive-scale proteome evaluation has routinely concerned digesting intact proteins adopted by inferred protein identification utilizing mass spectrometry. This ‘bottom-up’ course of affords a excessive variety of identifications (not at all times distinctive to a single gene).
Nevertheless, issues come up from incomplete or ambiguous characterization of different splice kinds, numerous modifications (for instance, acetylation and methylation) and endogenous protein cleavages, particularly when mixtures of those create advanced patterns of intact protein isoforms and species.
‘High-down’ interrogation of complete proteins can overcome these issues for particular person proteins, however has not been achieved on a proteome scale owing to the dearth of intact protein fractionation strategies which are effectively built-in with tandem mass spectrometry.
Right here we present, utilizing a brand new four-dimensional separation system, identification of 1,043 gene merchandise from human cells which are dispersed into greater than 3,000 protein species created by post-translational modification (PTM), RNA splicing and proteolysis.
The general system produced larger than 20-fold will increase in each separation energy and proteome protection, enabling the identification of proteins as much as 105 kDa and people with as much as 11 transmembrane helices. Many beforehand undetected isoforms of endogenous human proteins had been mapped, together with adjustments in multiply modified species in response to accelerated mobile ageing (senescence) induced by DNA harm.
Built-in with the newest model of the Swiss-Prot knowledgebase, the knowledge present exact correlations to particular person genes and proof-of-concept for large-scale interrogation of complete protein molecules. The know-how guarantees to enhance the hyperlink between proteomics knowledge and sophisticated phenotypes in fundamental biology and illness analysis.
Fluorescence probes used for detection of reactive oxygen species.

Remedy-induced senescence in most cancers.

Mobile senescence is a response to nonlethal stress that ends in persistent cytostasis with a definite morphological and biochemical phenotype. The senescence phenotype, detected in tumors by the expression of mRNA and protein markers, could be generated in most cancers cells missing practical p53 and retinoblastoma protein. Present analysis means that therapy-induced senescence (TIS) represents a novel practical goal which will enhance most cancers remedy.
TIS could be induced in immortal and reworked most cancers cells by chosen anticancer compounds or radiation, and accumulating knowledge point out that TIS could produce diminished toxicity-related unwanted effects and elevated tumor-specific immune exercise.
This evaluate examines the present standing of TIS-regulated mechanisms, brokers, and senescence biomarkers with the aim of encouraging additional growth of this method to most cancers remedy. Remaining hurdles embody the dearth of environment friendly senescence-inducing brokers and incomplete organic knowledge on tumor response. The identification of further compounds and different focused approaches to senescence induction will additional the event of TIS within the medical remedy of most cancers.
Fluorescence probes used for detection of reactive oxygen species.

The neurobiology and management of anxious states.

Concern is an adaptive element of the acute “stress” response to potentially-dangerous (exterior and inner) stimuli which threaten to perturb homeostasis. Nevertheless, when disproportional in depth, power and/or irreversible, or not related to any real threat, it could be symptomatic of a debilitating anxious state: for instance, social phobia, panic assaults or generalized nervousness dysfunction.
In view of the significance of guaranteeing an acceptable emotional response to aversive occasions, it isn’t shocking {that a} variety of mechanisms are concerned within the induction and inhibition of anxious states. Other than standard neurotransmitters, corresponding to monoamines, gamma-amino-butyric acid (GABA) and glutamate, many different modulators have been implicated, together with: adenosine, cannabinoids, quite a few neuropeptides, hormones, neurotrophins, cytokines and a number of other mobile mediators.
Accordingly, although benzodiazepines (which reinforce transmission at GABA(A) receptors), serotonin (5-HT)(1A) receptor agonists and 5-HT reuptake inhibitors are presently the precept medication employed within the administration of hysteria issues, there may be appreciable scope for the event of different therapies.
Along with mobile, anatomical and neurochemical methods, behavioral fashions are indispensable for the characterization of anxious states and their modulation. Amongst numerous paradigms, battle procedures–in which topics expertise opposing impulses of need and fear–are of especial conceptual and therapeutic pertinence.
For instance, within the Vogel Battle Check (VCT), the power of medicine to launch punishment-suppressed consuming conduct is evaluated. In reviewing the neurobiology of anxious states, the current article focuses particularly upon: the multifarious and sophisticated roles of particular person modulators, usually as a perform of the particular receptor sort and neuronal substrate concerned of their actions; novel targets for the administration of hysteria issues; the affect of neurotransmitters and different brokers upon efficiency within the VCT; knowledge acquired from complementary pharmacological and genetic methods and, lastly, a number of open questions prone to orientate future experimental- and clinical-analysis.

MUC16 Antibody
37173 100ul
EUR 319

MUC16 Antibody
37173-100ul 100ul
EUR 302.4

MUC16 Antibody
49089 100ul
EUR 499

MUC16 Antibody
49089-100ul 100ul
EUR 399.6

MUC16 Antibody
49089-50ul 50ul
EUR 286.8

MUC16 Antibody
49090 100ul
EUR 499

MUC16 Antibody
49090-100ul 100ul
EUR 399.6

MUC16 Antibody
49090-50ul 50ul
EUR 286.8

MUC16 Antibody
E037173 100μg/100μl
EUR 255
Description: Available in various conjugation types.

MUC16 Antibody
E033999 100μg/100μl
EUR 255
Description: Available in various conjugation types.

MUC16 Antibody
E11-11416C 100μg
EUR 225
Description: Available in various conjugation types.

MUC16 Antibody
E19-7989-1 50ug/50ul
EUR 145
Description: Available in various conjugation types.

MUC16 Antibody
E19-7989-2 100ug/100ul
EUR 225
Description: Available in various conjugation types.

MUC16 Antibody
CSB-PA899266- each
EUR 402
Description: A polyclonal antibody against MUC16. Recognizes MUC16 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IF;IF:1:100-1:500

MUC16 Antibody
CSB-PA899266-100ul 100ul
EUR 379.2
Description: A polyclonal antibody against MUC16. Recognizes MUC16 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IF;IF:1:100-1:500

MUC16 Antibody
1-CSB-PA015219GA01HU
  • Ask for price
  • Ask for price
  • 150ul
  • 50ul
Description: A polyclonal antibody against MUC16. Recognizes MUC16 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB

MUC16 Antibody
DF7989 200ul
EUR 420

MUC16 Antibody
DF7989-100ul 100ul
EUR 280

MUC16 Antibody
DF7989-200ul 200ul
EUR 350

MUC16 Antibody
E38PA9722 100ul
EUR 225
Description: Available in various conjugation types.

MUC16 Antibody
E38PA9791 100ul
EUR 225
Description: Available in various conjugation types.

MUC16 Antibody
CAC07541-100ug 100ug
EUR 314

MUC16 Antibody
CAC07541-50ug 50ug
EUR 199.2

MUC16 antibody
70R-15295 100 ug
EUR 302
Description: Rabbit polyclonal MUC16 antibody

MUC16 antibody
70R-32038 100 ug
EUR 294
Description: Rabbit polyclonal MUC16 antibody

MUC16 Antibody
1-CSB-PA070303
  • Ask for price
  • Ask for price
  • 100ug
  • 50ug
Description: A polyclonal antibody against MUC16. Recognizes MUC16 from Human. This antibody is Unconjugated. Tested in the following application: IF, ELISA;IF:1/200-1/1000.ELISA:1/20000

MUC16 Antibody
1-CSB-PA268943
  • Ask for price
  • Ask for price
  • 100ul
  • 50ul
Description: A polyclonal antibody against MUC16. Recognizes MUC16 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:1000-1:2000, IHC:1:15-1:50

MUC16 Antibody
1-CSB-PA10657A0Rb
  • Ask for price
  • Ask for price
  • 100ug
  • 50ug
Description: A polyclonal antibody against MUC16. Recognizes MUC16 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC; Recommended dilution: IHC:1:20-1:200

MUC16 Antibody
GWB-E6791E 0.5 ml Ask for price

MUC16 Antibody
MBS7136805-005mL 0.05mL
EUR 220

MUC16 Antibody
MBS7136805-01mL 0.1mL
EUR 300

MUC16 Antibody
MBS7136805-5x01mL 5x0.1mL
EUR 1350

MUC16 Antibody
MBS7136836-005mL 0.05mL
EUR 220

MUC16 Antibody
MBS7136836-01mL 0.1mL
EUR 300

MUC16 Antibody
MBS7136836-5x01mL 5x0.1mL
EUR 1350

MUC16 Antibody
MBS7130927-01mL 0.1mL
EUR 270

MUC16 Antibody
MBS7130927-5x01mL 5x0.1mL
EUR 1200

MUC16 Antibody
MBS7128000-005mL 0.05mL
EUR 190

MUC16 Antibody
MBS7128000-01mL 0.1mL
EUR 270

MUC16 Antibody
MBS7128000-5x01mL 5x0.1mL
EUR 1205

MUC16 Antibody
MBS7121285-005mg 0.05mg
EUR 150

MUC16 Antibody
MBS7121285-01mg 0.1mg
EUR 190

MUC16 Antibody
MBS7121285-5x01mg 5x0.1mg
EUR 845

MUC16 Antibody
MBS9404879-01mL 0.1mL
EUR 305

MUC16 Antibody
MBS9404879-5x01mL 5x0.1mL
EUR 1230

MUC16 Antibody
MBS9411443-005mL 0.05mL
EUR 245

MUC16 Antibody
MBS9411443-01mL 0.1mL
EUR 305

MUC16 Antibody
MBS9411443-5x01mL 5x0.1mL
EUR 1230

MUC16 Antibody
MBS9232726-01mL 0.1mL
EUR 415

MUC16 Antibody
MBS9232726-5x01mL 5x0.1mL
EUR 1841

MUC16 Antibody
MBS8584523-01mL 0.1mL
EUR 305

MUC16 Antibody
MBS8584523-01mLAF405L 0.1mL(AF405L)
EUR 465

MUC16 Antibody
MBS8584523-01mLAF405S 0.1mL(AF405S)
EUR 465

MUC16 Antibody
MBS8584523-01mLAF610 0.1mL(AF610)
EUR 465

MUC16 Antibody
MBS8584523-01mLAF635 0.1mL(AF635)
EUR 465

MUC16 Antibody
MBS8584592-01mL 0.1mL
EUR 305

MUC16 Antibody
MBS8584592-01mLAF405L 0.1mL(AF405L)
EUR 465

MUC16 Antibody
MBS8584592-01mLAF405S 0.1mL(AF405S)
EUR 465

MUC16 Antibody
MBS8584592-01mLAF610 0.1mL(AF610)
EUR 465

MUC16 Antibody
MBS8584592-01mLAF635 0.1mL(AF635)
EUR 465

MUC16 Antibody
MBS856468-01mg 0.1mg
EUR 305

MUC16 Antibody
MBS856468-01mLAF405L 0.1mL(AF405L)
EUR 465

MUC16 Antibody
MBS856468-01mLAF405S 0.1mL(AF405S)
EUR 465

MUC16 Antibody
MBS856468-01mLAF610 0.1mL(AF610)
EUR 465

MUC16 Antibody
MBS856468-01mLAF635 0.1mL(AF635)
EUR 465

MUC16 Antibody
MBS8517282-005mg 0.05mg
EUR 235

MUC16 Antibody
MBS8517282-01mg 0.1mg
EUR 305

MUC16 Antibody
MBS8517282-01mLAF405M 0.1mL(AF405M)
EUR 465

MUC16 Antibody
MBS8517282-01mLAF546 0.1mL(AF546)
EUR 465

MUC16 Antibody
MBS8517282-01mLAF750 0.1mL(AF750)
EUR 465

MUC16 Antibody
MBS9435863-005mL 0.05mL
EUR 325

MUC16 Antibody
MBS9435863-01mL 0.1mL
EUR 435

MUC16 Antibody
MBS9435863-5x01mL 5x0.1mL
EUR 1810

MUC16 Antibody
MBS9435864-005mL 0.05mL
EUR 325

MUC16 Antibody
MBS9435864-01mL 0.1mL
EUR 435

MUC16 Antibody
MBS9435864-5x01mL 5x0.1mL
EUR 1810

MUC16 Antibody
MBS9608483-01mL 0.1mL
EUR 260

MUC16 Antibody
MBS9608483-02mL 0.2mL
EUR 305

MUC16 Antibody
MBS9608483-5x02mL 5x0.2mL
EUR 1220

MUC16 Antibody
MBS9505374-005mL 0.05mL
EUR 285

MUC16 Antibody
MBS9505374-01mL 0.1mL
EUR 385

MUC16 Antibody
MBS9505374-5x01mL 5x0.1mL
EUR 1590

MUC16 Antibody
ABD7989 100 ug
EUR 525.6

MUC16 antibody (HRP)
60R-1720 100 ug
EUR 302
Description: Rabbit polyclonal MUC16 antibody (HRP)

MUC16 antibody (HRP)
MBS5310359-01mg 0.1mg
EUR 510

MUC16 antibody (HRP)
MBS5310359-5x01mg 5x0.1mg
EUR 2150

MUC16 antibody (FITC)
60R-1721 100 ug
EUR 302
Description: Rabbit polyclonal MUC16 antibody (FITC)

MUC16 antibody (FITC)
MBS5310360-01mg 0.1mg
EUR 510

MUC16 antibody (FITC)
MBS5310360-5x01mg 5x0.1mg
EUR 2150

MUC16 Antibody / CA125
V8758-100UG 100 ug
EUR 349.3
Description: CA125 also known as mucin 16, is a member of the mucin family glycoproteins. CA125 is a component of the ocular surface (including the cornea and conjunctiva), the respiratory tract and the female reproductive tract epithelia. Since CA125 is highly glycosylated it creates a hydrophilic environment that acts as a lubricating barrier against foreign particles and infectious agents on the apical membrane of epithelial cells. CA125 reacts with both normal tissues and neoplasms of fallopian tube, endometrium, endocervix and mesothelioma. It does not react with colon cancer. Normal tissues such as breast, liver, skin, kidney and spleen are also negative. Studies have shown that CA125 reacts with approximately 80% of epithelial ovarian neoplasms of serous, endometrioid, clear cell and undifferentiated types. No reactivity has been shown for mucinous ovarian tumors or in germ cell or hematopoietic tumors. This antibody is a useful aid for classification of a variety of tumors, such as some adenocarcinomas of the colon, breast carcinomas, malignant mesothelioma, uterine adenomatoid tumor, lung bronchoalveolar carcinoma, and ovarian endometrioid and serous carcinomas.

MUC16 Antibody / CA125
V8758-20UG 20 ug
EUR 153.3
Description: CA125 also known as mucin 16, is a member of the mucin family glycoproteins. CA125 is a component of the ocular surface (including the cornea and conjunctiva), the respiratory tract and the female reproductive tract epithelia. Since CA125 is highly glycosylated it creates a hydrophilic environment that acts as a lubricating barrier against foreign particles and infectious agents on the apical membrane of epithelial cells. CA125 reacts with both normal tissues and neoplasms of fallopian tube, endometrium, endocervix and mesothelioma. It does not react with colon cancer. Normal tissues such as breast, liver, skin, kidney and spleen are also negative. Studies have shown that CA125 reacts with approximately 80% of epithelial ovarian neoplasms of serous, endometrioid, clear cell and undifferentiated types. No reactivity has been shown for mucinous ovarian tumors or in germ cell or hematopoietic tumors. This antibody is a useful aid for classification of a variety of tumors, such as some adenocarcinomas of the colon, breast carcinomas, malignant mesothelioma, uterine adenomatoid tumor, lung bronchoalveolar carcinoma, and ovarian endometrioid and serous carcinomas.

MUC16 Antibody / CA125
V8758SAF-100UG 100 ug
EUR 349.3
Description: CA125 also known as mucin 16, is a member of the mucin family glycoproteins. CA125 is a component of the ocular surface (including the cornea and conjunctiva), the respiratory tract and the female reproductive tract epithelia. Since CA125 is highly glycosylated it creates a hydrophilic environment that acts as a lubricating barrier against foreign particles and infectious agents on the apical membrane of epithelial cells. CA125 reacts with both normal tissues and neoplasms of fallopian tube, endometrium, endocervix and mesothelioma. It does not react with colon cancer. Normal tissues such as breast, liver, skin, kidney and spleen are also negative. Studies have shown that CA125 reacts with approximately 80% of epithelial ovarian neoplasms of serous, endometrioid, clear cell and undifferentiated types. No reactivity has been shown for mucinous ovarian tumors or in germ cell or hematopoietic tumors. This antibody is a useful aid for classification of a variety of tumors, such as some adenocarcinomas of the colon, breast carcinomas, malignant mesothelioma, uterine adenomatoid tumor, lung bronchoalveolar carcinoma, and ovarian endometrioid and serous carcinomas.

MUC16 Antibody / CA125
V8230-100UG 100 ug
EUR 424.15
Description: The mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs). Membrane-associated and secretory Mucins are high molecular weight glycoproteins of the glycocalyx (polysaccharide biofilm) that protects mucosal epithelium from particulate matter and microorganisms. Epithelial Mucins are large, secreted and cell surface glycoproteins crucial for adhesion modulation, signaling and epithelial cell protection. The number of repeats is highly polymorphic and varies among different alleles. The Mucin family consists of Mucins 1-4, Mucin 5 (AC and B), Mucins 6-8, Mucins 11-13 and Mucins 15-17. The Mucin 16 protein (also commonly referred to as CA125), encoded for by the gene MUC16, is a very high molecular weight tumor antigen consisting of three domains: a carboxy terminal domain, an extracellular domain and an amino terminal domain. Mucin 16, an ovarian cancer-associated antigen, is used as a marker to monitor the progress of epithelial ovarian cancer. It is a hydrophilic membrane-associated protein that may be involved in vitamin A functions.

MUC16 Antibody / CA125
V8230-20UG 20 ug
EUR 186.15
Description: The mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs). Membrane-associated and secretory Mucins are high molecular weight glycoproteins of the glycocalyx (polysaccharide biofilm) that protects mucosal epithelium from particulate matter and microorganisms. Epithelial Mucins are large, secreted and cell surface glycoproteins crucial for adhesion modulation, signaling and epithelial cell protection. The number of repeats is highly polymorphic and varies among different alleles. The Mucin family consists of Mucins 1-4, Mucin 5 (AC and B), Mucins 6-8, Mucins 11-13 and Mucins 15-17. The Mucin 16 protein (also commonly referred to as CA125), encoded for by the gene MUC16, is a very high molecular weight tumor antigen consisting of three domains: a carboxy terminal domain, an extracellular domain and an amino terminal domain. Mucin 16, an ovarian cancer-associated antigen, is used as a marker to monitor the progress of epithelial ovarian cancer. It is a hydrophilic membrane-associated protein that may be involved in vitamin A functions.

MUC16 Antibody / CA125
V8230SAF-100UG 100 ug
EUR 424.15
Description: The mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs). Membrane-associated and secretory Mucins are high molecular weight glycoproteins of the glycocalyx (polysaccharide biofilm) that protects mucosal epithelium from particulate matter and microorganisms. Epithelial Mucins are large, secreted and cell surface glycoproteins crucial for adhesion modulation, signaling and epithelial cell protection. The number of repeats is highly polymorphic and varies among different alleles. The Mucin family consists of Mucins 1-4, Mucin 5 (AC and B), Mucins 6-8, Mucins 11-13 and Mucins 15-17. The Mucin 16 protein (also commonly referred to as CA125), encoded for by the gene MUC16, is a very high molecular weight tumor antigen consisting of three domains: a carboxy terminal domain, an extracellular domain and an amino terminal domain. Mucin 16, an ovarian cancer-associated antigen, is used as a marker to monitor the progress of epithelial ovarian cancer. It is a hydrophilic membrane-associated protein that may be involved in vitamin A functions.

MUC16 Antibody / CA125
V8373-100UG 100 ug
EUR 424.15
Description: The mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs). Membrane-associated and secretory Mucins are high molecular weight glycoproteins of the glycocalyx (polysaccharide biofilm) that protects mucosal epithelium from particulate matter and microorganisms. Epithelial Mucins are large, secreted and cell surface glycoproteins crucial for adhesion modulation, signaling and epithelial cell protection. The number of repeats is highly polymorphic and varies among different alleles. The Mucin family consists of Mucins 1-4, Mucin 5 (AC and B), Mucins 6-8, Mucins 11-13 and Mucins 15-17. The Mucin 16 protein (also commonly referred to as CA125), encoded for by the gene MUC16, is a very high molecular weight tumor antigen consisting of three domains: a carboxy terminal domain, an extracellular domain and an amino terminal domain. Mucin 16, an ovarian cancer-associated antigen, is used as a marker to monitor the progress of epithelial ovarian cancer. It is a hydrophilic membrane-associated protein that may be involved in vitamin A functions.

MUC16 Antibody / CA125
V8373-20UG 20 ug
EUR 186.15
Description: The mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs). Membrane-associated and secretory Mucins are high molecular weight glycoproteins of the glycocalyx (polysaccharide biofilm) that protects mucosal epithelium from particulate matter and microorganisms. Epithelial Mucins are large, secreted and cell surface glycoproteins crucial for adhesion modulation, signaling and epithelial cell protection. The number of repeats is highly polymorphic and varies among different alleles. The Mucin family consists of Mucins 1-4, Mucin 5 (AC and B), Mucins 6-8, Mucins 11-13 and Mucins 15-17. The Mucin 16 protein (also commonly referred to as CA125), encoded for by the gene MUC16, is a very high molecular weight tumor antigen consisting of three domains: a carboxy terminal domain, an extracellular domain and an amino terminal domain. Mucin 16, an ovarian cancer-associated antigen, is used as a marker to monitor the progress of epithelial ovarian cancer. It is a hydrophilic membrane-associated protein that may be involved in vitamin A functions.

MUC16 Antibody / CA125
V8373SAF-100UG 100 ug
EUR 424.15
Description: The mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs). Membrane-associated and secretory Mucins are high molecular weight glycoproteins of the glycocalyx (polysaccharide biofilm) that protects mucosal epithelium from particulate matter and microorganisms. Epithelial Mucins are large, secreted and cell surface glycoproteins crucial for adhesion modulation, signaling and epithelial cell protection. The number of repeats is highly polymorphic and varies among different alleles. The Mucin family consists of Mucins 1-4, Mucin 5 (AC and B), Mucins 6-8, Mucins 11-13 and Mucins 15-17. The Mucin 16 protein (also commonly referred to as CA125), encoded for by the gene MUC16, is a very high molecular weight tumor antigen consisting of three domains: a carboxy terminal domain, an extracellular domain and an amino terminal domain. Mucin 16, an ovarian cancer-associated antigen, is used as a marker to monitor the progress of epithelial ovarian cancer. It is a hydrophilic membrane-associated protein that may be involved in vitamin A functions.

MUC16 Antibody / CA125
V3648-100UG 100 ug
EUR 349.3
Description: The mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs). Membrane-associated and secretory mucins are high molecular weight glycoproteins of the glycocalyx (polysaccharide biofilm) that protects mucosal epithelium from particulate matter and microorganisms. Epithelial mucins are large, secreted and cell surface glycoproteins crucial for adhesion modulation, signaling and epithelial cell protection. The number of repeats is highly polymorphic and varies among different alleles. The Mucin family consists of Mucins 1-4, Mucin 5 (AC and B), 6-8, 11-13 and 15-17. The Mucin 16 protein (also commonly referred to as CA125), encoded for by the gene MUC16, is a very high molecular weight tumor antigen consisting of three domains: a carboxy terminal domain, an extracellular domain and an amino terminal domain. Mucin 16, an ovarian cancer-associated antigen, is used as a marker to monitor the progress of epithelial ovarian cancer. It is a hydrophilic membrane-associated protein that may be involved in vitamin A functions.

MUC16 Antibody / CA125
V3648-20UG 20 ug
EUR 153.3
Description: The mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs). Membrane-associated and secretory mucins are high molecular weight glycoproteins of the glycocalyx (polysaccharide biofilm) that protects mucosal epithelium from particulate matter and microorganisms. Epithelial mucins are large, secreted and cell surface glycoproteins crucial for adhesion modulation, signaling and epithelial cell protection. The number of repeats is highly polymorphic and varies among different alleles. The Mucin family consists of Mucins 1-4, Mucin 5 (AC and B), 6-8, 11-13 and 15-17. The Mucin 16 protein (also commonly referred to as CA125), encoded for by the gene MUC16, is a very high molecular weight tumor antigen consisting of three domains: a carboxy terminal domain, an extracellular domain and an amino terminal domain. Mucin 16, an ovarian cancer-associated antigen, is used as a marker to monitor the progress of epithelial ovarian cancer. It is a hydrophilic membrane-associated protein that may be involved in vitamin A functions.

MUC16 Antibody / CA125
V3648IHC-7ML 7 ml
EUR 349.3
Description: The mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs). Membrane-associated and secretory mucins are high molecular weight glycoproteins of the glycocalyx (polysaccharide biofilm) that protects mucosal epithelium from particulate matter and microorganisms. Epithelial mucins are large, secreted and cell surface glycoproteins crucial for adhesion modulation, signaling and epithelial cell protection. The number of repeats is highly polymorphic and varies among different alleles. The Mucin family consists of Mucins 1-4, Mucin 5 (AC and B), 6-8, 11-13 and 15-17. The Mucin 16 protein (also commonly referred to as CA125), encoded for by the gene MUC16, is a very high molecular weight tumor antigen consisting of three domains: a carboxy terminal domain, an extracellular domain and an amino terminal domain. Mucin 16, an ovarian cancer-associated antigen, is used as a marker to monitor the progress of epithelial ovarian cancer. It is a hydrophilic membrane-associated protein that may be involved in vitamin A functions.

MUC16 Antibody / CA125
V3648SAF-100UG 100 ug
EUR 349.3
Description: The mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs). Membrane-associated and secretory mucins are high molecular weight glycoproteins of the glycocalyx (polysaccharide biofilm) that protects mucosal epithelium from particulate matter and microorganisms. Epithelial mucins are large, secreted and cell surface glycoproteins crucial for adhesion modulation, signaling and epithelial cell protection. The number of repeats is highly polymorphic and varies among different alleles. The Mucin family consists of Mucins 1-4, Mucin 5 (AC and B), 6-8, 11-13 and 15-17. The Mucin 16 protein (also commonly referred to as CA125), encoded for by the gene MUC16, is a very high molecular weight tumor antigen consisting of three domains: a carboxy terminal domain, an extracellular domain and an amino terminal domain. Mucin 16, an ovarian cancer-associated antigen, is used as a marker to monitor the progress of epithelial ovarian cancer. It is a hydrophilic membrane-associated protein that may be involved in vitamin A functions.

MUC16 Antibody / CA125
V3494-100UG 100 ug
EUR 424.15
Description: The mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs). Membrane-associated and secretory mucins are high molecular weight glycoproteins of the glycocalyx (polysaccharide biofilm) that protects mucosal epithelium from particulate matter and microorganisms. Epithelial mucins are large, secreted and cell surface glycoproteins crucial for adhesion modulation, signaling and epithelial cell protection. The number of repeats is highly polymorphic and varies among different alleles. The Mucin family consists of Mucins 1-4, Mucin 5 (AC and B), 6-8, 11-13 and 15-17. The Mucin 16 protein (also commonly referred to as CA125), encoded for by the gene MUC16, is a very high molecular weight tumor antigen consisting of three domains: a carboxy terminal domain, an extracellular domain and an amino terminal domain. Mucin 16, an ovarian cancer-associated antigen, is used as a marker to monitor the progress of epithelial ovarian cancer. It is a hydrophilic membrane-associated protein that may be involved in vitamin A functions.

MUC16 Antibody / CA125
V3494-20UG 20 ug
EUR 186.15
Description: The mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs). Membrane-associated and secretory mucins are high molecular weight glycoproteins of the glycocalyx (polysaccharide biofilm) that protects mucosal epithelium from particulate matter and microorganisms. Epithelial mucins are large, secreted and cell surface glycoproteins crucial for adhesion modulation, signaling and epithelial cell protection. The number of repeats is highly polymorphic and varies among different alleles. The Mucin family consists of Mucins 1-4, Mucin 5 (AC and B), 6-8, 11-13 and 15-17. The Mucin 16 protein (also commonly referred to as CA125), encoded for by the gene MUC16, is a very high molecular weight tumor antigen consisting of three domains: a carboxy terminal domain, an extracellular domain and an amino terminal domain. Mucin 16, an ovarian cancer-associated antigen, is used as a marker to monitor the progress of epithelial ovarian cancer. It is a hydrophilic membrane-associated protein that may be involved in vitamin A functions.

MUC16 Antibody / CA125
V3494IHC-7ML 7 ml
EUR 424.15
Description: The mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs). Membrane-associated and secretory mucins are high molecular weight glycoproteins of the glycocalyx (polysaccharide biofilm) that protects mucosal epithelium from particulate matter and microorganisms. Epithelial mucins are large, secreted and cell surface glycoproteins crucial for adhesion modulation, signaling and epithelial cell protection. The number of repeats is highly polymorphic and varies among different alleles. The Mucin family consists of Mucins 1-4, Mucin 5 (AC and B), 6-8, 11-13 and 15-17. The Mucin 16 protein (also commonly referred to as CA125), encoded for by the gene MUC16, is a very high molecular weight tumor antigen consisting of three domains: a carboxy terminal domain, an extracellular domain and an amino terminal domain. Mucin 16, an ovarian cancer-associated antigen, is used as a marker to monitor the progress of epithelial ovarian cancer. It is a hydrophilic membrane-associated protein that may be involved in vitamin A functions.

MUC16 Antibody / CA125
V3494SAF-100UG 100 ug
EUR 424.15
Description: The mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs). Membrane-associated and secretory mucins are high molecular weight glycoproteins of the glycocalyx (polysaccharide biofilm) that protects mucosal epithelium from particulate matter and microorganisms. Epithelial mucins are large, secreted and cell surface glycoproteins crucial for adhesion modulation, signaling and epithelial cell protection. The number of repeats is highly polymorphic and varies among different alleles. The Mucin family consists of Mucins 1-4, Mucin 5 (AC and B), 6-8, 11-13 and 15-17. The Mucin 16 protein (also commonly referred to as CA125), encoded for by the gene MUC16, is a very high molecular weight tumor antigen consisting of three domains: a carboxy terminal domain, an extracellular domain and an amino terminal domain. Mucin 16, an ovarian cancer-associated antigen, is used as a marker to monitor the progress of epithelial ovarian cancer. It is a hydrophilic membrane-associated protein that may be involved in vitamin A functions.

MUC16 antibody (biotin)
60R-1722 100 ug
EUR 302
Description: Rabbit polyclonal MUC16 antibody (biotin)

MUC16 antibody (biotin)
MBS5310361-01mg 0.1mg
EUR 510

MUC16 antibody (biotin)
MBS5310361-5x01mg 5x0.1mg
EUR 2150

MUC16,CA125 Antibody
abx235429-100ug 100 ug
EUR 661.2

MUC16,CA125 Antibody
abx235430-100ug 100 ug
EUR 610.8

MUC16,CA125 Antibody
abx235429-100g 100 µg
EUR 350

MUC16,CA125 Antibody
abx235430-100g 100 µg
EUR 350

MUC16 Monoclonal Antibody
E10-31941P 100μg/100μl
EUR 225
Description: Available in various conjugation types.

MUC16 Polyclonal Antibody
E910005 100ul
EUR 225
Description: Available in various conjugation types.

MUC16 Conjugated Antibody
C37173 100ul
EUR 476.4

MUC16 Conjugated Antibody
C49089 100ul
EUR 476.4

MUC16 Polyclonal Antibody
A54125
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 µg
  • 20 ul
  • 50 ul
  • 100 ul

MUC16 Polyclonal Antibody
A71345
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  • Ask for price
  • 50 ul
  • 100 ul

MUC16 Polyclonal Antibody
MBS8566211-01mL 0.1mL
EUR 305

MUC16 Polyclonal Antibody
MBS8566211-01mLAF405L 0.1mL(AF405L)
EUR 565

MUC16 Polyclonal Antibody
MBS8566211-01mLAF405S 0.1mL(AF405S)
EUR 565

MUC16 Polyclonal Antibody
MBS8566211-01mLAF610 0.1mL(AF610)
EUR 565

MUC16 Polyclonal Antibody
MBS8566211-01mLAF635 0.1mL(AF635)
EUR 565

MUC16 Polyclonal Antibody
MBS9129130-002mL 0.02mL
EUR 200

MUC16 Polyclonal Antibody
MBS9129130-005mL 0.05mL
EUR 255

MUC16 Polyclonal Antibody
MBS9129130-01mL 0.1mL
EUR 345

MUC16 Polyclonal Antibody
MBS9129130-02mL 0.2mL
EUR 545

MUC16 Polyclonal Antibody
MBS9129130-5x02mL 5x0.2mL
EUR 2265

MUC16 Polyclonal Antibody
MBS2524578-002mL 0.02mL
EUR 140

MUC16 Polyclonal Antibody
MBS2524578-006mL 0.06mL
EUR 180

MUC16 Polyclonal Antibody
MBS2524578-012mL 0.12mL
EUR 260

MUC16 Polyclonal Antibody
MBS2524578-02mL 0.2mL
EUR 405

MUC16 Conjugated Antibody
MBS9447616-01mLAF350 0.1mL(AF350)
EUR 480

MUC16 Conjugated Antibody
MBS9447616-01mLAF405 0.1mL(AF405)
EUR 480

MUC16 Conjugated Antibody
MBS9447616-01mLAF488 0.1mL(AF488)
EUR 480

MUC16 Conjugated Antibody
MBS9447616-01mLAF555 0.1mL(AF555)
EUR 480

MUC16 Conjugated Antibody
MBS9447616-01mLBiotin 0.1mL(Biotin)
EUR 480

MUC16 Conjugated Antibody
MBS9456791-01mLAF350 0.1mL(AF350)
EUR 480

MUC16 Conjugated Antibody
MBS9456791-01mLAF405 0.1mL(AF405)
EUR 480

MUC16 Conjugated Antibody
MBS9456791-01mLAF488 0.1mL(AF488)
EUR 480

MUC16 Conjugated Antibody
MBS9456791-01mLAF555 0.1mL(AF555)
EUR 480

MUC16 Conjugated Antibody
MBS9456791-01mLBiotin 0.1mL(Biotin)
EUR 480

MUC16 Polyclonal Antibody
RD265725A-120uL 120μL
EUR 360
Description: This gene encodes a protein that is a member of the mucin family. Mucins are high molecular weight, O-glycosylated proteins that play an important role in forming a protective mucous barrier, and are found on the apical surfaces of the epithelia. The encoded protein is a membrane-tethered mucin that contains an extracellular domain at its amino terminus, a large tandem repeat domain, and a transmembrane domain with a short cytoplasmic domain. The amino terminus is highly glycosylated, while the repeat region contains 156 amino acid repeats unit that are rich in serines, threonines, and prolines. Interspersed within the repeats are Sea urchin sperm protein Enterokinase and Agrin (SEA) modules, leucine-rich repeats and ankyrin (ANK) repeats. These regions together form the ectodomain, and there is a potential cleavage site found near an SEA module close to the transmembrane domain. This protein is thought to play a role in forming a barrier, protecting epithelial cells from pathogens. Products of this gene have been used as a marker for different cancers, with higher expression levels associated with poorer outcomes.

MUC16 Polyclonal Antibody
RD265725A-200uL 200μL
EUR 630
Description: This gene encodes a protein that is a member of the mucin family. Mucins are high molecular weight, O-glycosylated proteins that play an important role in forming a protective mucous barrier, and are found on the apical surfaces of the epithelia. The encoded protein is a membrane-tethered mucin that contains an extracellular domain at its amino terminus, a large tandem repeat domain, and a transmembrane domain with a short cytoplasmic domain. The amino terminus is highly glycosylated, while the repeat region contains 156 amino acid repeats unit that are rich in serines, threonines, and prolines. Interspersed within the repeats are Sea urchin sperm protein Enterokinase and Agrin (SEA) modules, leucine-rich repeats and ankyrin (ANK) repeats. These regions together form the ectodomain, and there is a potential cleavage site found near an SEA module close to the transmembrane domain. This protein is thought to play a role in forming a barrier, protecting epithelial cells from pathogens. Products of this gene have been used as a marker for different cancers, with higher expression levels associated with poorer outcomes.

MUC16 Polyclonal Antibody
RD265725A-60uL 60μL
EUR 204
Description: This gene encodes a protein that is a member of the mucin family. Mucins are high molecular weight, O-glycosylated proteins that play an important role in forming a protective mucous barrier, and are found on the apical surfaces of the epithelia. The encoded protein is a membrane-tethered mucin that contains an extracellular domain at its amino terminus, a large tandem repeat domain, and a transmembrane domain with a short cytoplasmic domain. The amino terminus is highly glycosylated, while the repeat region contains 156 amino acid repeats unit that are rich in serines, threonines, and prolines. Interspersed within the repeats are Sea urchin sperm protein Enterokinase and Agrin (SEA) modules, leucine-rich repeats and ankyrin (ANK) repeats. These regions together form the ectodomain, and there is a potential cleavage site found near an SEA module close to the transmembrane domain. This protein is thought to play a role in forming a barrier, protecting epithelial cells from pathogens. Products of this gene have been used as a marker for different cancers, with higher expression levels associated with poorer outcomes.

MUC16 monoclonal antibody
MB66107 50ul
EUR 158
Description: Mouse

MUC16 monoclonal antibody
MB66176 50ul
EUR 158
Description: Mouse

MUC16 polyclonal antibody
BS90892 50ul
EUR 258
Description: Rabbit

MUC16 polyclonal antibody
BS90893 50ul
EUR 258
Description: Rabbit

MUC16 polyclonal antibody
BS74315 50ul
EUR 208
Description: Rabbit

Mucin 16 (MUC16) Antibody
abx036002-100ug 100 ug
EUR 469.2

Mucin-16 (MUC16) Antibody
abx113889-100l 100 µl
EUR 612.5

Mucin-16 (MUC16) Antibody
abx036002-100g 100 µg
EUR 337.5

Mucin-16 (MUC16) Antibody
abx135924-100tests 100 tests
EUR 175

Mucin-16 (MUC16) Antibody
abx430563-200l 200 µl
EUR 250

Mucin-16 (MUC16) Antibody
abx339194-100g 100 µg Ask for price

Mucin-16 (MUC16) Antibody
abx339194-20g 20 µg
EUR 250

Mucin-16 (MUC16) Antibody
abx339194-50g 50 µg
EUR 350

Mucin-16 (MUC16) Antibody
abx402517-100tests 100 tests
EUR 287.5

Mucin-16 (MUC16) Antibody
abx402564-100tests 100 tests
EUR 287.5

Mucin-16 (Muc16) Antibody
abx432168-100g 100 µg
EUR 250

Mucin-16 (MUC16) Antibody
abx322829-100g 100 µg
EUR 250

Mucin-16 (MUC16) Antibody
abx322829-50g 50 µg
EUR 187.5

Mucin-16 (MUC16) Antibody
abx013727-100l 100 µl
EUR 43.75

Mucin-16 (MUC16) Antibody
abx110007-100l 100 µl
EUR 162.5

Anti-CA125 / MUC16 antibody
STJ180025 0.1 ml
EUR 265.2

Anti-CA125 / MUC16 antibody
STJ180303 0.1 ml
EUR 258

MUC16 Antibody, HRP conjugated
1-CSB-PA10657B0Rb
  • Ask for price
  • Ask for price
  • 100ug
  • 50ug
Description: A polyclonal antibody against MUC16. Recognizes MUC16 from Human. This antibody is HRP conjugated. Tested in the following application: ELISA

MUC16 Antibody HRP Conjugated
MBS9459751-01mL 0.1mL
EUR 595

MUC16 Antibody HRP Conjugated
MBS9459751-5x01mL 5x0.1mL
EUR 2525

MUC16 Antibody, FITC conjugated
1-CSB-PA10657C0Rb
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  • 100ug
  • 50ug
Description: A polyclonal antibody against MUC16. Recognizes MUC16 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

OACD02105-1ML - MUC16 Antibody
OACD02105-1ML 1ml
EUR 609

MUC16 Antibody FITC Conjugated
MBS9459752-01mL 0.1mL
EUR 595

MUC16 Antibody FITC Conjugated
MBS9459752-5x01mL 5x0.1mL
EUR 2525

anti- MUC16,CA125 antibody
FNab05429 100µg
EUR 702
Description: Antibody raised against MUC16,CA125

anti- MUC16,CA125 antibody
FNab05430 100µg
EUR 658.5
Description: Antibody raised against MUC16,CA125

OACA04211-50UG - MUC16 Antibody
OACA04211-50UG 50ug
EUR 179

OAAF08246-50UL - MUC16 Antibody
OAAF08246-50UL 50ul
EUR 219

MUC16 Antibody, Biotin conjugated
1-CSB-PA10657D0Rb
  • Ask for price
  • Ask for price
  • 100ug
  • 50ug
Description: A polyclonal antibody against MUC16. Recognizes MUC16 from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA

OACD02105-100UL - MUC16 Antibody
OACD02105-100UL 100ul
EUR 179

OACA04211-100UG - MUC16 Antibody
OACA04211-100UG 100ug
EUR 319

OAAF08246-100UL - MUC16 Antibody
OAAF08246-100UL 100ul
EUR 329

OAAF02579-100UG - MUC16 Antibody
OAAF02579-100UG 100ug
EUR 329
In view of the latest proliferation of mechanisms implicated within the pathogenesis, modulation and, probably, remedy of hysteria issues, that is an opportune second to survey their practical and pathophysiological significance, and to evaluate their affect upon efficiency within the VCT and different fashions of potential anxiolytic properties.

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