Redefining oxidative stress.

Oxidative stress is usually outlined as an imbalance of pro-oxidants and antioxidants, which could be quantified in people because the redox state of plasma GSH/GSSG. Plasma GSH redox in people turns into oxidized with age, in response to oxidative stress (chemotherapy, smoking), and in frequent illnesses (kind 2 diabetes, heart problems).
Nevertheless, information additionally present that redox of plasma GSH/GSSG just isn’t equilibrated with the bigger plasma cysteine/cystine (Cys/CySS) pool, indicating that the “stability” of pro-oxidants and antioxidants can’t be outlined by a single entity. The most important mobile thiol/disulfide programs, together with GSH/GSSG, thioredoxin- 1 (-SH(2)/-SS-), and Cys/CySS, usually are not in redox equilibrium and reply in another way to chemical toxicants and physiologic stimuli.
Particular person signaling and management occasions happen by means of discrete redox pathways quite than by means of mechanisms which are immediately conscious of a world thiol/disulfide stability similar to that conceptualized within the frequent definition of oxidative stress.
Thus, from a mechanistic standpoint, oxidative stress could also be higher outlined as a disruption of redox signaling and management. Adoption of such a definition may redirect analysis to determine key perturbations of redox signaling and management and result in new therapies for oxidative stress-related illness processes.

Complete evaluation of kinase inhibitor selectivity.

We examined the interplay of 72 kinase inhibitors with 442 kinases protecting >80% of the human catalytic protein kinome. Our information present that, as a category, kind II inhibitors are extra selective than kind I inhibitors, however that there are vital exceptions to this development. The information additional illustrate that selective inhibitors have been developed towards the vast majority of kinases focused by the compounds examined.
Evaluation of the interplay patterns reveals a category of ‘group-selective’ inhibitors broadly lively towards a single subfamily of kinases, however selective outdoors that subfamily. The information set suggests compounds to make use of as instruments to check kinases for which no devoted inhibitors exist.
It additionally supplies a basis for additional exploring kinase inhibitor biology and toxicity, in addition to for finding out the structural foundation of the noticed interplay patterns. Our findings will assist to appreciate the direct enabling potential of genomics for drug growth and fundamental analysis about mobile signaling.

Omega-Three fatty acids and heart problems: results on danger components, molecular pathways, and scientific occasions.

We reviewed obtainable proof for cardiovascular results of n-Three polyunsaturated fatty acid (PUFA) consumption, specializing in lengthy chain (seafood) n-Three PUFA, together with their principal dietary sources, results on physiological danger components, potential molecular pathways and bioactive metabolites, results on particular scientific endpoints, and present dietary pointers.
Main dietary sources embrace fatty fish and different seafood. n-Three PUFA consumption lowers plasma triglycerides, resting coronary heart fee, and blood stress and may additionally enhance myocardial filling and effectivity, decrease irritation, and enhance vascular operate.
Experimental research exhibit direct anti-arrhythmic results, which have been difficult to doc in people. n-Three PUFA have an effect on a myriad of molecular pathways, together with alteration of bodily and chemical properties of mobile membranes, direct interplay with and modulation of membrane channels and proteins, regulation of gene expression through nuclear receptors and transcription components, modifications in eicosanoid profiles, and conversion of n-Three PUFA to bioactive metabolites.
In potential observational research and adequately powered randomized scientific trials, advantages of n-Three PUFA appear most constant for coronary coronary heart illness mortality and sudden cardiac loss of life. Potential results on different cardiovascular outcomes are less-well-established, together with conflicting proof from observational research and/or randomized trials for results on nonfatal myocardial infarction, ischemic stroke, atrial fibrillation, recurrent ventricular arrhythmias, and coronary heart failure.
 Analysis gaps embrace the relative significance of various physiological and molecular mechanisms, exact dose-responses of physiological and scientific results, whether or not fish oil supplies all the advantages of fish consumption, and scientific results of plant-derived n-Three PUFA.
Total, present information present sturdy concordant proof that n-Three PUFA are bioactive compounds that cut back danger of cardiac loss of life. Nationwide and worldwide pointers have converged on constant suggestions for the final inhabitants to devour no less than 250 mg/day of long-chain n-Three PUFA or no less than 2 servings/week of oily fish.

A circuitry mannequin of the expression of behavioral sensitization to amphetamine-like psychostimulants.

Repeated publicity to psychostimulants similar to cocaine and amphetamine produces behavioral sensitization, which is characterised by an augmented locomotor response to a subsequent psychostimulant problem injection. Experimentation centered on the neural underpinnings of behavioral sensitization has progressed from a singular concentrate on dopamine transmission within the nucleus accumbens and striatum to the research of mobile and molecular mechanisms that happen all through the neural circuitry wherein the mesocorticolimbic dopamine projections are embedded.
This analysis effort has yielded a conglomerate of information that has resisted easy interpretations, primarily as a result of no single neuronal impact is prone to be accountable for the expression of behavioral sensitization. The current evaluation examines the literature and critically evaluates the extent to which the neural penalties of repeated psychostimulant administration are related to the expression of behavioral sensitization.
The neural alterations discovered to contribute to the long-term expression of behavioral sensitization are centered in a set of interconnected limbic nuclei, that are termed the ‘motive’ circuit. This neural circuit is used as a template to arrange the related biochemical and molecular findings right into a mannequin of the expression of behavioral sensitization.

Oxidative stress as a significant wrongdoer in kidney illness in diabetes.

It’s postulated that localized tissue oxidative stress is a key element within the growth of diabetic nephropathy. There stays controversy, nonetheless, as as to whether that is an early hyperlink between hyperglycemia and renal illness or develops as a consequence of different major pathogenic mechanisms.
Within the kidney, a variety of pathways that generate reactive oxygen species (ROS) similar to glycolysis, particular defects within the polyol pathway, uncoupling of nitric oxide synthase, xanthine oxidase, NAD(P)H oxidase, and superior glycation have been recognized as doubtlessly main contributors to the pathogenesis of diabetic kidney illness.
As well as, a unifying speculation has been proposed whereby mitochondrial manufacturing of ROS in response to persistent hyperglycemia often is the key initiator for every of those pathogenic pathways. This postulate emphasizes the significance of mitochondrial dysfunction within the development and growth of diabetes issues together with nephropathy.
A thriller stays, nonetheless, as to why antioxidants per se have demonstrated minimal renoprotection in people regardless of constructive preclinical analysis findings. It’s doubtless that the utility of present research approaches, similar to vitamin use, will not be the perfect antioxidant technique in human diabetic nephropathy.

PTPN11 (Ab-580) Antibody

CSB-PA961746-
EUR 402
Description: A polyclonal antibody against PTPN11 (Ab-580). Recognizes PTPN11 (Ab-580) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:1000, IHC:1:50-1:200, IF:1:100-1:200

PTPN11 (Ab-580) Antibody

CSB-PA961746-100ul 100ul
EUR 379.2
Description: A polyclonal antibody against PTPN11 (Ab-580). Recognizes PTPN11 (Ab-580) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:1000, IHC:1:50-1:200, IF:1:100-1:200

MemBriteâ„¢ Fix 568/580

30095 1KIT
EUR 772.8
Description: Minimum order quantity: 1 unit of 1KIT

hsa-miR-580 Primers

MPH01878 150 ul / 10 uM
EUR 145.2

SHP-2 (Ab-580) Antibody

21320-100ul 100ul
EUR 302.4

SHP-2 (Ab-580) Antibody

21320-50ul 50ul
EUR 224.4

PYK2 (Phospho-Tyr579/580) Antibody

13230-100ul 100ul
EUR 302.4

PYK2 (Phospho-Tyr579/580) Antibody

13230-50ul 50ul
EUR 224.4

anti-SHP-2 (Ab-580)

LF-PA20454 100 ul
EUR 400.8
Description: Rabbit polyclonal to SHP-2

hsa-miR-580 miRNA Inhibitor

MIH03164 2 x 5.0 nmol
EUR 211.2

hsa-miR-580-3p Primers

MPH03331 150 ul / 10 uM
EUR 145.2

hsa-miR-580-5p Primers

MPH03332 150 ul / 10 uM
EUR 145.2

hsa-miR-580 miRNA Antagomir

MNH03164 2 x 5.0 nmol
EUR 394.8

mFluor™ Blue 580 SE

1178 1 mg
EUR 318

DIPAK LONG

CPDI000L1 EACH
EUR 304.62

Serpin A1c Recombinant Protein

91-580 0.05 mg
EUR 821.4
Description: Alpha-1-antitrypsin 1-3(SERPIN A1) is a secreted protein and belongs to the serpin family. Serpins bind the protease active site resulting in a major conformational rearrangement that traps the enzyme in a covalent acyl-enzyme intermediate. Mouse SERPIN A1 is a serine protease inhibitor whose targets include elastase,plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema orliver disease. Several transcript variants encoding the same protein have been found for this gene.

Kallikrein 7 Recombinant Protein

92-580 0.05 mg
EUR 821.4
Description: Kallikrein7, also named as stratum corneum chymotryptic enzyme (SCCE), is a secreted protein of the Kallikrein-related peptidase (KLK) family. This family contains fifteen homologous secreted serine endopeptidases and plays a significant role in various physiological processes, including skin desquamation, semen liquefaction, neural plasticity, and body fluid homeostasis. In skin KLK5, KLK 7 and KLK14 are able to degrade corneodesmosomes, which leads to desquamation of skin surface cells. KLK activation is believed to be mediated through highly organized proteolytic cascades, regulated through a series of feedback loops, inhibitors, auto-degradation and internal cleavages. Studies have shown that one potential physiological activator for KLK7 is KLK5. Along with KLK14, these three kallikreins form a proteolytic cascade in the stratum corneum. KLK7 is primarily expressed in the skin but is also detected at relatively high levels in esophagus, heart, liver, central nervous system, kidney, pancreas, mammary and salivary glands.

PYK2 (Phospho-Tyr579/580) Conjugated Antibody

C13230 100ul
EUR 476.4

Phospho-PYK2 (Tyr579/580) Blocking Peptide

AF7383-BP 1mg
EUR 234

Mesothelin / MSLN (296-580) Recombinant Protein

11-216 0.1 mg
EUR 714.3
Description: Mesothelin (MSLN) is also known as CAK1 antigen, Pre-pro-megakaryocyte-potentiating factor, which belongs to the mesothelin family. Mesothelin / MSLN can be proteolytically cleaved into the following two chains by a furin-like convertase: Megakaryocyte-potentiating factor (MPF) and the cleaved form of mesothelin. Both MPF and the cleaved form of mesothelin are N-glycosylated. Mesothelin / MSLN can interacts with MUC16. The membrane-anchored forms of MSLN may play a role in cellular adhesion. MPF potentiates megakaryocyte colony formation in vitro.

MemBriteâ„¢ Fix 568/580, Trial Size

30095-T 1KIT
EUR 266.4
Description: Minimum order quantity: 1 unit of 1KIT

DAX-J2™ Ratio 580/460

16310 1 mg
EUR 471.6

Zinc Finger Protein 580 (ZNF580) Antibody

abx030431-400ul 400 ul
EUR 627.6

Zinc Finger Protein 580 (ZNF580) Antibody

abx030431-80l 80 µl
EUR 343.2

Recombinant human Zinc finger protein 580

P2142 100ug Ask for price
Description: Recombinant protein for human Zinc finger protein 580

hsa-miR-580-3p miRNA Inhibitor

MIH03165 2 x 5.0 nmol
EUR 211.2

hsa-miR-580-5p miRNA Inhibitor

MIH03166 2 x 5.0 nmol
EUR 211.2

hsa-miR-580-3p miRNA Antagomir

MNH03165 2 x 5.0 nmol
EUR 394.8

hsa-miR-580-5p miRNA Antagomir

MNH03166 2 x 5.0 nmol
EUR 394.8

Long trebler phosphoramidite

A8151-250 250 mg
EUR 408
Description: Long trebler phosphoramidite is a branching reagent for oligonucleotide synthesis allowing to synthesize branched DNA structures using standard DNA synthesizer.

Wick 100mm Long

BUR4508 PK10
EUR 6.27

CytoFix™ BCECF, AM *Optimized for long term cellular pH tracking*

21200 1 mg
EUR 318

Human B Cell Leukemia X long ELISA kit

E01B0575-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Human B Cell Leukemia X long in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human B Cell Leukemia X long ELISA kit

E01B0575-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Human B Cell Leukemia X long in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human B Cell Leukemia X long ELISA kit

E01B0575-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Human B Cell Leukemia X long in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat B Cell Leukemia X long ELISA kit

E02B0575-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat B Cell Leukemia X long in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat B Cell Leukemia X long ELISA kit

E02B0575-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rat B Cell Leukemia X long in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat B Cell Leukemia X long ELISA kit

E02B0575-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rat B Cell Leukemia X long in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig B Cell Leukemia X long ELISA kit

E07B0575-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Porcine B Cell Leukemia X long in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig B Cell Leukemia X long ELISA kit

E07B0575-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Porcine B Cell Leukemia X long in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig B Cell Leukemia X long ELISA kit

E07B0575-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Porcine B Cell Leukemia X long in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog B Cell Leukemia X long ELISA kit

E08B0575-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Canine B Cell Leukemia X long in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog B Cell Leukemia X long ELISA kit

E08B0575-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Canine B Cell Leukemia X long in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog B Cell Leukemia X long ELISA kit

E08B0575-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Canine B Cell Leukemia X long in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey B Cell Leukemia X long ELISA kit

E09B0575-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Monkey B Cell Leukemia X long in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey B Cell Leukemia X long ELISA kit

E09B0575-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Monkey B Cell Leukemia X long in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey B Cell Leukemia X long ELISA kit

E09B0575-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Monkey B Cell Leukemia X long in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse B Cell Leukemia X long ELISA kit

E03B0575-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Mouse B Cell Leukemia X long in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse B Cell Leukemia X long ELISA kit

E03B0575-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Mouse B Cell Leukemia X long in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse B Cell Leukemia X long ELISA kit

E03B0575-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Mouse B Cell Leukemia X long in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat B Cell Leukemia X long ELISA kit

E06B0575-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Goat B Cell Leukemia X long in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat B Cell Leukemia X long ELISA kit

E06B0575-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Goat B Cell Leukemia X long in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat B Cell Leukemia X long ELISA kit

E06B0575-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Goat B Cell Leukemia X long in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit B Cell Leukemia X long ELISA kit

E04B0575-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rabbit B Cell Leukemia X long in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit B Cell Leukemia X long ELISA kit

E04B0575-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rabbit B Cell Leukemia X long in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit B Cell Leukemia X long ELISA kit

E04B0575-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rabbit B Cell Leukemia X long in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Nunc Cell Factory PC connector none sterile long

140099 PK10
EUR 287.28

CytoSelect Cell Transformation Assay (Cell Recovery Compatible), Colorimetric

CBA-135 96 assays
EUR 985.2
Description: CytoSelect 96-Well Cell Transformation Assays (Cell Recovery Compatible) provide a robust system for detecting transformed cells, screening cell transformation inhibitors, and determining in vitro drug sensitivity. A proprietary modified soft agar matrix allows you to either quantify cells using the included fluorescent dye, or recover the cells for further analysis.

CytoSelect Cell Transformation Assay (Cell Recovery Compatible), Colorimetric

CBA-135-5 5 x 96 assays
EUR 4027.2
Description: CytoSelect 96-Well Cell Transformation Assays (Cell Recovery Compatible) provide a robust system for detecting transformed cells, screening cell transformation inhibitors, and determining in vitro drug sensitivity. A proprietary modified soft agar matrix allows you to either quantify cells using the included fluorescent dye, or recover the cells for further analysis.

CytoSelect Cell Transformation Assay (Cell Recovery Compatible), Fluorometric

CBA-140 96 assays
EUR 1027.2
Description: CytoSelect 96-Well Cell Transformation Assays (Cell Recovery Compatible) provide a robust system for detecting transformed cells, screening cell transformation inhibitors, and determining in vitro drug sensitivity. A proprietary modified soft agar matrix allows you to either quantify cells using the included fluorescent dye, or recover the cells for further analysis.

CytoSelect Cell Transformation Assay (Cell Recovery Compatible), Fluorometric

CBA-140-5 5 x 96 assays
EUR 4179.6
Description: CytoSelect 96-Well Cell Transformation Assays (Cell Recovery Compatible) provide a robust system for detecting transformed cells, screening cell transformation inhibitors, and determining in vitro drug sensitivity. A proprietary modified soft agar matrix allows you to either quantify cells using the included fluorescent dye, or recover the cells for further analysis.

293AD Cell Line

AD-100 1 vial
EUR 553.2
Description: The 293AD Cell Line is derived from the parental 293 cells but selected for attributes that increase adenovirus production, including firmer attachment and larger surface area.

293AAV Cell Line

AAV-100 1 vial
EUR 609.6
Description: The 293AAV Cell Line is derived from the parental 293 cells but selected for attributes that increase AAV production, including firmer attachment and larger surface area.

293LTV Cell Line

LTV-100 1 vial
EUR 609.6
Description: The 293LTV Cell Line is derived from the parental 293 cells but selected for attributes that increase lentiviral production, including fimrer attachment and larger surface area.

293RTV Cell Line

RV-100 1 vial
EUR 609.6
Description: The 293RTV Cell Line is derived from the parental 293 cells but selected for attributes that increase retroviral production, including fimrer attachment and larger surface area.

RSV (Strain Long) Protein

abx069909-1ml 1 ml
EUR 393.6

RSV (Long Strain) Protein

abx069910-1mg 1 mg
EUR 2498.4

RSV Long Strain Protein

abx060644-100ug 100 ug
EUR 1161.6

DISC1-long-specific Antibody

abx232397-100ug 100 ug
EUR 610.8

Pateur glass long plugged

PIP4106 PK250
EUR 106.75

PROGARD 2S ALONE (LONG)

PR0G000S2 EACH
EUR 456

Bend Long 1019 Interchange

GLA3090 EACH
EUR 13.11

Bend Long 1423 Interchange

GLA3092 EACH
EUR 13.11

Bend Long 1926 Interchange

GLA3094 EACH
EUR 13.11

Bend Long 2429 Interchange

GLA3096 EACH
EUR 13.57

Bend Long 2932 Interchange

GLA3098 EACH
EUR 13.45

Electroporation Cuvettes 1mm Long

FBR-201 PK50
EUR 121.98

Electroporation Cuvettes 2mm Long

FBR-202 PK50
EUR 119.7

Electroporation Cuvettes 4mm Long

FBR-204 PK50
EUR 121.98

Long Feather scalpel n11

DD530038 PK20
EUR 53.58

Kinesis VacuTight Headless Long

CHR4571 EACH
EUR 5.84

Pasteur pipette 5.75in long

CLS7095B5X-1000EA PK1000
EUR 59.28

Tongs Furnace 460mm Long

TON1104 EACH
EUR 157.32

Human Zinc finger protein 580, ZNF580 ELISA KIT

ELI-51274h 96 Tests
EUR 988.8

Mouse Zinc finger protein 580, Znf580 ELISA KIT

ELI-51275m 96 Tests
EUR 1038

Human pre-microRNA Expression Construct Lenti-miR-580

PMIRH580PA-1 Bacterial Streak
EUR 820.8

Recombinant Toxoplasma Gondii MIC4 Protein (aa 1-580)

VAng-0439Lsx-inquire inquire Ask for price
Description: Toxoplasma Gondii Micronemal protein 4, recombinant protein.

Human MSLN Protein (Glu 296-Gly 580) [Fc]

VAng-2562Lsx-100g 100 µg
EUR 984
Description: Human Mesothelin protein, human IgG1 Fc tag, was expressed in human 293 cells. (Uniprot ID: AAH09272)

Human MSLN Protein (Glu 296-Gly 580) [Fc]

VAng-2562Lsx-1mg 1 mg
EUR 5998.8
Description: Human Mesothelin protein, human IgG1 Fc tag, was expressed in human 293 cells. (Uniprot ID: AAH09272)

Human MSLN Protein (Glu 296-Gly 580) [His]

VAng-2563Lsx-100g 100 µg
EUR 1099.2
Description: Human Mesothelin protein, His tag, was expressed in human 293 cells. (Uniprot ID: AAH09272)

Human MSLN Protein (Glu 296-Gly 580) [His]

VAng-2563Lsx-1mg 1 mg
EUR 6592.8
Description: Human Mesothelin protein, His tag, was expressed in human 293 cells. (Uniprot ID: AAH09272)

Recombinant Pseudomonas Aeruginosa PA14_21660 Protein (aa 1-580)

VAng-Cr0847-1mgEcoli 1 mg (E. coli)
EUR 8961.6
Description: Pseudomonas Aeruginosa (strain UCBPP-PA14) UPF0060 membrane protein PA14_21660, recombinant protein.

Recombinant Pseudomonas Aeruginosa PA14_21660 Protein (aa 1-580)

VAng-Cr0847-500gEcoli 500 µg (E. coli)
EUR 6040.8
Description: Pseudomonas Aeruginosa (strain UCBPP-PA14) UPF0060 membrane protein PA14_21660, recombinant protein.

Recombinant Pseudomonas Aeruginosa PA14_21660 Protein (aa 1-580)

VAng-Cr0847-50gEcoli 50 µg (E. coli)
EUR 4104
Description: Pseudomonas Aeruginosa (strain UCBPP-PA14) UPF0060 membrane protein PA14_21660, recombinant protein.

Recombinant Mycobacterium Avium mhpA Protein (aa 1-580)

VAng-Yyj2652-inquire inquire Ask for price
Description: Mycobacterium Avium (strain 104) 3- (3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase (mhpA), recombinant protein.

Recombinant Mycobacterium Paratuberculosis mhpA Protein (aa 1-580)

VAng-Yyj0966-inquire inquire Ask for price
Description: Mycobacterium Paratuberculosis 3- (3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase (mhpA), recombinant protein.

Recombinant Mycobacterium Avium mhpA Protein(aa 1-580)

VAng-Yyj1323-inquire inquire Ask for price
Description: Mycobacterium Avium (strain 104) 3- (3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase (mhpA), recombinant protein.

Recombinant Brucella Abortus fliF Protein (aa 1-580)

VAng-Lsx4789-inquire inquire Ask for price
Description: Brucella Abortus biovar 1 (strain 9-941) Flagellar M-ring protein, recombinant protein.

Recombinant Mycobacterium Marinum fadD28 Protein (aa 1-580)

VAng-Yyj4351-inquire inquire Ask for price
Description: Mycobacterium Marinum (strain ATCC BAA-535 / M) Long-chain-fatty-acid--AMP ligase FadD28 (fadD28), recombinant protein.

Recombinant Mycobacterium Abscessus proS Protein (aa 1-580)

VAng-Yyj5520-inquire inquire Ask for price
Description: Mycobacterium Abscessus (strain ATCC 19977 / DSM 44196) Proline--tRNA ligase (proS), recombinant protein.

StemTAG Stem Cell Colony Formation Assay (Cell Recovery Compatible)

CBA-325 96 assays
EUR 1027.2
Description: Our StemTAG 96-Well Stem Cell Colony Formation Assay provides a high-throughput method to quantify ES cells in just 7-10 days, and no manual cell counting is required. Once colonies are formed, they may be analyzed in three different ways: 1. Lyse cells, then quantify in a fluorescence plate reader using dye included in the kit; 2. Lyse cells, then quantify alkaline phosphatase activity using reagents provided; or 3. Recover colonies from matrix for further culture or analysis.

StemTAG Stem Cell Colony Formation Assay (Cell Recovery Compatible)

CBA-325-5 5 x 96 assays
EUR 4033.2
Description: Our StemTAG 96-Well Stem Cell Colony Formation Assay provides a high-throughput method to quantify ES cells in just 7-10 days, and no manual cell counting is required. Once colonies are formed, they may be analyzed in three different ways: 1. Lyse cells, then quantify in a fluorescence plate reader using dye included in the kit; 2. Lyse cells, then quantify alkaline phosphatase activity using reagents provided; or 3. Recover colonies from matrix for further culture or analysis.

CytoSelect Cell Transformation Assay (Cell Recovery Compatible), Colorimetric, Trial Size

CBA-135-T 24 assays
EUR 518.4
Description: CytoSelect 96-Well Cell Transformation Assays (Cell Recovery Compatible) provide a robust system for detecting transformed cells, screening cell transformation inhibitors, and determining in vitro drug sensitivity. A proprietary modified soft agar matrix allows you to either quantify cells using the included fluorescent dye, or recover the cells for further analysis.

293/GFP Cell Line

AKR-200 1 vial
EUR 686.4
Description: 293/GFP Cell Line stably expresses GFP and otherwise exhibits the same characteristics of the parental cell line.

T47D/GFP Cell Line

AKR-208 1 vial
EUR 686.4
Description: T47D/GFP Cell Line stably expresses GFP and otherwise exhibits the same characteristics of the parental cell line.

A549/GFP Cell Line

AKR-209 1 vial
EUR 686.4
Description: A549/GFP Cell Line stably expresses GFP and otherwise exhibits the same characteristics of the parental cell line.

HeLa/GFP Cell Line

AKR-213 1 vial
EUR 686.4
Description: HeLa/GFP Cell Line stably expresses GFP and otherwise exhibits the same characteristics of the parental cell line.

NIH3T3/GFP Cell Line

AKR-214 1 vial
EUR 686.4
Description: NIH3T3/GFP Cell Line stably expresses GFP and otherwise exhibits the same characteristics of the parental cell line.

NIH3T3/Cas9 Cell Line

AKR-5104 1 vial
EUR 686.4

293/Cas9 Cell Line

AKR-5110 1 vial
EUR 686.4

HeLa/Cas9 Cell Line

AKR-5111 1 vial
EUR 686.4

CytoSelect 96-Well Cell Transformation Assay (Cell Recovery Compatible, Fluorometric), Trial Size

CBA-140-T 24 assays
EUR 547.2
Description: CytoSelect 96-Well Cell Transformation Assays (Cell Recovery Compatible) provide a robust system for detecting transformed cells, screening cell transformation inhibitors, and determining in vitro drug sensitivity. A proprietary modified soft agar matrix allows you to either quantify cells using the included fluorescent dye, or recover the cells for further analysis.

Collagen-based Cell Contraction Assay

CBA-201 24 assays
EUR 582
Description: Cell Biolabs? Collagen-based Contraction Assay Kit provides a simple system to assess cell contractivity in vitro and screen cell contraction mediators. Each kit provides sufficient quantities to perform up to 24 assays in a 24-well plate. The kit can be also used in culturing cells in 3D collagen matrix.

CytoSelect MTT Cell Proliferation Assay

CBA-252 960 assays
EUR 490.8
Description: Cell Biolabs? CytoSelect MTT Cell Proliferation Assay provides a colorimetric format for measuring and monitoring cell proliferation.  The kit contains sufficient reagents for the evaluation of 960 assays in 96-well plates or 192 assays in 24-well plates.  Cells can be plated and then treated with compounds or agents that affect proliferation.  Cells are then detected with the proliferation reagent, which is converted in live cells from the yellow tetrazole MTT to the purple formazan form by a cellular reductase (Figure 1).  An increase in cell proliferation is accompanied by an increased signal, while a decrease in cell proliferation (and signal) can indicate the toxic effects of compounds or suboptimal culture conditions.  The assay principles are basic and can be applied to most eukaryotic cell lines, including adherent and non-adherent cells and certain tissues.  This cell proliferation reagent can be used to detect proliferation in bacteria, yeast, fungi, protozoa as well as cultured mammalian and piscine cells.

SKOV-3/Luc Cell Line

AKR-232 1 vial
EUR 686.4
Description: SKOV-3/Luc Cell Line stably expresses luciferase and otherwise exhibits the same characteristics of the parental cell line.

MCF-7/Luc Cell Line

AKR-234 1 vial
EUR 686.4
Description: MCF-7/Luc Cell Line stably expresses luciferase and otherwise exhibits the same characteristics of the parental cell line.

OVCAR-5/RFP Cell Line

AKR-254 1 vial
EUR 686.4
Description: OVCAR-5/RFP Cell Line stably expresses RFP and otherwise exhibits the same characteristics of the parental cell line.

Guinea pig B Cell Leukemia X long ELISA kit

E05B0575-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Guinea pig B Cell Leukemia X long in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig B Cell Leukemia X long ELISA kit

E05B0575-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Guinea pig B Cell Leukemia X long in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig B Cell Leukemia X long ELISA kit

E05B0575-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Guinea pig B Cell Leukemia X long in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Recombinant C1q R1 Protein (Thr 22-Lys 580) [His]

VAng-1141Lsx-1mg 1 mg
EUR 5998.8
Description: Human C1q R1 (CD93), His tag, is expressed in HEK 293 cells. (Uniprot ID: AAH28075)

Recombinant C1q R1 Protein (Thr 22-Lys 580) [His]

VAng-1141Lsx-50g 50 µg
EUR 1017.6
Description: Human C1q R1 (CD93), His tag, is expressed in HEK 293 cells. (Uniprot ID: AAH28075)

Biotinylated Human MSLN Protein (Glu 296-Gly 580) [Fc]

VAng-2560Lsx-200g 200 µg
EUR 4184.4
Description: Biotinylated Human Mesothelin protein, human IgG1 Fc tag, was expressed in human 293 cells. (Uniprot ID: AAH09272.1)

Biotinylated Human MSLN Protein (Glu 296-Gly 580) [Fc]

VAng-2560Lsx-25g 25 µg
EUR 1017.6
Description: Biotinylated Human Mesothelin protein, human IgG1 Fc tag, was expressed in human 293 cells. (Uniprot ID: AAH09272.1)

Biotinylated Human MSLN Protein (Glu 296-Gly 580) [His]

VAng-2561Lsx-200g 200 µg
EUR 4184.4
Description: Biotinylated Human Mesothelin protein, His tag, was expressed in human 293 cells. (Uniprot ID: AAH09272.1)

Biotinylated Human MSLN Protein (Glu 296-Gly 580) [His]

VAng-2561Lsx-25g 25 µg
EUR 1017.6
Description: Biotinylated Human Mesothelin protein, His tag, was expressed in human 293 cells. (Uniprot ID: AAH09272.1)

Recombinant Plasmodium Falciparum MSP-1 Protein (aa 200-580)

VAng-Wyb6594-1mgEcoli 1 mg (E. coli)
EUR 5536.8
Description: Plasmodium Falciparum (isolate Wellcome) Merozoite surface protein 1, recombinant protein.

Recombinant Plasmodium Falciparum MSP-1 Protein (aa 200-580)

VAng-Wyb6594-500gEcoli 500 µg (E. coli)
EUR 3921.6
Description: Plasmodium Falciparum (isolate Wellcome) Merozoite surface protein 1, recombinant protein.

Recombinant Plasmodium Falciparum MSP-1 Protein (aa 200-580)

VAng-Wyb6594-50gEcoli 50 µg (E. coli)
EUR 2683.2
Description: Plasmodium Falciparum (isolate Wellcome) Merozoite surface protein 1, recombinant protein.

CytoSelect 24-well Cell Invasion, Fluorometric

CBA-111 12 assays
EUR 714
Description: The ability of malignant tumor cells to invade normal surrounding tissue contributes in large part to the morbidity and mortality of cancers. Cell invasion requires several distinct cellular functions including adhesion, motility, detachment, and extracellular matrix proteolysis. Our CytoSelect Cell Invasion Assays utilize precoated inserts to assay the invasive properties of tumor cells. Invasive cells can be quantified in 24-well plates on either a standard microplate reader or a fluorescence plate reader. Inserts are precoated on the top of the membrane with ECM matrix gel (basement membrane), a protein mix isolated from EHS tumor cells.

CytoSelect 96-well Cell Invasion, Fluorometric

CBA-112 96 assays
EUR 908.4
Description: The ability of malignant tumor cells to invade normal surrounding tissue contributes in large part to the morbidity and mortality of cancers. Cell invasion requires several distinct cellular functions including adhesion, motility, detachment, and extracellular matrix proteolysis. Our CytoSelect 96-Well Cell Invasion Assays utilize precoated inserts to assay the invasive properties of tumor cells. Invasive cells can be quantified in 96-well plates on a fluorescence plate reader. Inserts are precoated on the top of the membrane with Basement Membrane, an ECM protein mix isolated from EHS tumor cells.

Radius 24-Well Cell Migration Assay

CBA-125 24 assays
EUR 602.4
Description: The Radius Cell Migration Assay provides a unique alternative to conventional cell migration assays using the Boyden chamber. Unlike Boyden chamber assays which may only be analyzed at endpoint, the Radius assay uses a proprietary cell culture plate containing a carefully-defined biocompatible hydrogel (Radius gel) spot centralized at the bottom of each well. When cells are seeded in the well, they will attach everywhere except on the Radius gel, creating a cell-free zone. Following cell seeding the Radius gel is removed, allowing migratory cells to move across the area and close the gap.

Radius 24-Well Cell Migration Assay

CBA-125-5 5 x 24 assays
EUR 2362.8
Description: The Radius Cell Migration Assay provides a unique alternative to conventional cell migration assays using the Boyden chamber. Unlike Boyden chamber assays which may only be analyzed at endpoint, the Radius assay uses a proprietary cell culture plate containing a carefully-defined biocompatible hydrogel (Radius gel) spot centralized at the bottom of each well. When cells are seeded in the well, they will attach everywhere except on the Radius gel, creating a cell-free zone. Following cell seeding the Radius gel is removed, allowing migratory cells to move across the area and close the gap.
There may be now an growing physique of information to counsel that methods involving a extra focused antioxidant method, utilizing brokers that penetrate particular mobile compartments, often is the elusive additive remedy required to additional optimize renoprotection in diabetes.

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