Triptolide (T10) is a standard anti-inflammatory and analgesic drug. Nonetheless, the activation of microglia and elimination of the corresponding inflammatory response are new targets for the remedy of neuropathic ache. Chemokine CCL (CCL2) is a key mediator for activating microglia. … Read More
The p53 tumor suppressor protein has well-established roles in monitoring numerous forms of stress alerts by activating particular transcriptional targets that management cell cycle arrest and apoptosis, though some actions are additionally mediated in a transcription-independent method. Right here, we … Read More
Oxidative stress is usually outlined as an imbalance of pro-oxidants and antioxidants, which could be quantified in people because the redox state of plasma GSH/GSSG. Plasma GSH redox in people turns into oxidized with age, in response to oxidative stress … Read More