Reaching for the cloud: on the lessons learned from grid computing technology transfer process to the biomedical community.

The primary goal of this mission consists within the improvement of a biomedical instrumentation prototype for acquisition, processing and transmission of biomedical alerts. These biomedical alerts are acquired after which processed with a microcontroller. After processing, all knowledge are despatched to a communication interface that may ship this data to a private laptop or a cellular phone.

The prototype developed, which is a digital blood stress meter, is meant to permit distant monitoring of sufferers dwelling in areas with restricted entry to medical help or scarce medical sources. We consider that this improvement could possibly be useful to enhance folks’s high quality of life, in addition to to permit an enchancment within the authorities attendance indices.

We study how the biomedical informatics (BMI) neighborhood, particularly consortia that share knowledge and functions, can benefit from a brand new useful resource referred to as “cloud computing”. Clouds typically provide sources on demand. In most clouds, expenses are pay per use, based mostly on giant farms of cheap, devoted servers, typically supporting parallel computing. Substantial economies of scale doubtlessly yield prices a lot decrease than devoted laboratory techniques and even institutional knowledge facilities.

General, even with conservative assumptions, for functions that aren’t I/O intensive and don’t demand a totally mature atmosphere, the numbers prompt that clouds can typically present main enhancements, and needs to be significantly thought of for BMI. Methodologically, it was very advantageous to formulate analyses when it comes to element applied sciences; specializing in these specifics enabled us to bypass the cacophony of other definitions (e.g., precisely what does a cloud embrace) and to investigate alternate options that make use of among the element applied sciences (e.g., an establishment’s knowledge middle).

Relative analyses had been one other nice simplifier. Quite than itemizing absolutely the strengths and weaknesses of cloud-based techniques (e.g., for safety or knowledge preservation), we deal with the modifications from a selected place to begin, e.g., particular person lab techniques. We regularly discover a tough parity (in precept), however one wants to look at particular person acquisitions–is a loosely managed lab transferring to a nicely managed cloud, or a tightly managed hospital knowledge middle transferring to a poorly safeguarded cloud?

This paper supplies an summary of multidimensional AM-FM strategies for analyzing medical pictures and movies. During the last decade, a number of new AM-FM demodulation strategies have been developed. We offer a dialogue of what many of those strategies share in widespread, and provides some particulars on current, Hilbert-based approaches.

Medical picture functions vary from medical picture segmentation, decision enhancement, classification, reconstruction to new strategies for video movement estimation. A short abstract of options for future work on this space can also be given.

Lately, we’ve got launched a transillumination approach for biomedical analysis. The approach, pass-through photon-based transillumination, depends on interferometric measurements to recuperate the knowledge of curiosity. On this work, we current the forward-calculated analytical interferograms that describe the habits of the system. Stochastic modeling of radiation interacting with tissue permits dedication of amplitude and part parameters, indispensable for computation of the interferograms.

Anti-LAMP3 antibody (Alexa-fluor 647)
STJ170006	St John's Laboratory	100 µg	EUR 393
Description: The dendritic cell lysosomal-associated membrane protein (DC-LAMP)/CD208 is a type I integral transmembrane glycoprotein mostly homologous to CD68, of about 45 kDa in mouse and 90 kDa in human (glycosylation), with a bipartite C-terminal structure divided by a serine/proline rich region, a transmembrane domain and a conserved tyrosine-based lysosomal targeting motif in its cytoplasmic tail. Initially cloned as a specific marker of human mature dendritic cells (DCs), DC-LAMP has been subsequently shown to be expressed in alveolar type II pneumocytes. In both cell types, the molecule is found in the limiting membrane of intracellular multi-lamellar bodies, known as MIIC (MHC class II compartments) in human mature DCs and as lung surfactant-containing lamellar bodies in type II pneumocytes. In the latter cell type, DC-LAMP expression is also detected at the cell surface.

Anti-IL3RA antibody (Alexa-fluor 488)
STJ170009	St John's Laboratory	100 µg	EUR 393
Description: IL3 exerts its biologic activity through its interaction with a cell surface receptor that consists of two subunits. The a subunit (CD123) specifically binds IL3, whereas the ß subunit is required for signaling and is common to the GMCSFR and IL5-R. 107D2.08 and 106C2.02 mAbs were obtained after mouse immunization with sorted human tonsillar PDC. Both clones strongly stain PDCs and basophils, weakly stain monocytes, CD34+ derived DCs and CD11c+ DC, while no staining is observed on T, B, NK cells as well as on mono-derived DCs. Staining with 107D2.08 and 106C2.02 mAbs are maintained on sorted PDC cultured in the presence of IL3 and CD40L, but lost when IL3 alone is added to the culture. The recognition of the IL3Ra chain by 107D2.08 and 106C2.02 was confirmed by transfection studies. 107D2.08 appeared to be the most appropriate clone for in situ studies. 107D2.08 allowed the first observation of IL3Ra+ cells in breast tumor microenvironment

Anti-IL3RA antibody (Alexa-fluor 546)
STJ170010	St John's Laboratory	100 µg	EUR 393
Description: IL3 exerts its biologic activity through its interaction with a cell surface receptor that consists of two subunits. The a subunit (CD123) specifically binds IL3, whereas the ß subunit is required for signaling and is common to the GMCSFR and IL5-R. 107D2.08 and 106C2.02 mAbs were obtained after mouse immunization with sorted human tonsillar PDC. Both clones strongly stain PDCs and basophils, weakly stain monocytes, CD34+ derived DCs and CD11c+ DC, while no staining is observed on T, B, NK cells as well as on mono-derived DCs. Staining with 107D2.08 and 106C2.02 mAbs are maintained on sorted PDC cultured in the presence of IL3 and CD40L, but lost when IL3 alone is added to the culture. The recognition of the IL3Ra chain by 107D2.08 and 106C2.02 was confirmed by transfection studies. 107D2.08 appeared to be the most appropriate clone for in situ studies. 107D2.08 allowed the first observation of IL3Ra+ cells in breast tumor microenvironment

Anti-IL3RA antibody (Alexa-fluor 647)
STJ170011	St John's Laboratory	100 µg	EUR 393
Description: IL3 exerts its biologic activity through its interaction with a cell surface receptor that consists of two subunits. The a subunit (CD123) specifically binds IL3, whereas the ß subunit is required for signaling and is common to the GMCSFR and IL5-R. 107D2.08 and 106C2.02 mAbs were obtained after mouse immunization with sorted human tonsillar PDC. Both clones strongly stain PDCs and basophils, weakly stain monocytes, CD34+ derived DCs and CD11c+ DC, while no staining is observed on T, B, NK cells as well as on mono-derived DCs. Staining with 107D2.08 and 106C2.02 mAbs are maintained on sorted PDC cultured in the presence of IL3 and CD40L, but lost when IL3 alone is added to the culture. The recognition of the IL3Ra chain by 107D2.08 and 106C2.02 was confirmed by transfection studies. 107D2.08 appeared to be the most appropriate clone for in situ studies. 107D2.08 allowed the first observation of IL3Ra+ cells in breast tumor microenvironment

Anti-CD207 antibody (Alexa-fluor 488)
STJ170014	St John's Laboratory	100 µg	EUR 393
Description: Langerin/CD207 is a transmembrane C-type lectin receptor (CLR) of epidermal and mucosal Langerhans cells (LCs) that induces Birbeck's granule formation. Langerin features a single carbohydrate recognition domain (CRD) with mannose-type specificity in its extracellular portion. Langerin is unique among the CLRs in that it contains an intracellular domain with a proline-rich motif. Langerin expression has not been reported outside the DC system. (Valladeau J et al, 1999, Eur.J.Immunol., 29:2695-2704; Valladeau J et al, 2000 Immunity, 12 : 71-81; Kashihara M et al, 1986, J.Invest.Derm., 87 :602-607 Ito T et al, 1999, J.Immunol., 163 :1409-1419 ;Saeland S & Valladeau J, CD207 (Langerin) Workshop reports 2002, Leukocyte-Typing VII, White Cell Diff Antigens, D. Mason et al, Eds, Oxford University Press:306-307)

Anti-CD207 antibody (Alexa-fluor 546)
STJ170015	St John's Laboratory	100 µg	EUR 393
Description: Langerin/CD207 is a transmembrane C-type lectin receptor (CLR) of epidermal and mucosal Langerhans cells (LCs) that induces Birbeck's granule formation. Langerin features a single carbohydrate recognition domain (CRD) with mannose-type specificity in its extracellular portion. Langerin is unique among the CLRs in that it contains an intracellular domain with a proline-rich motif. Langerin expression has not been reported outside the DC system. (Valladeau J et al, 1999, Eur.J.Immunol., 29:2695-2704; Valladeau J et al, 2000 Immunity, 12 : 71-81; Kashihara M et al, 1986, J.Invest.Derm., 87 :602-607 Ito T et al, 1999, J.Immunol., 163 :1409-1419 ;Saeland S & Valladeau J, CD207 (Langerin) Workshop reports 2002, Leukocyte-Typing VII, White Cell Diff Antigens, D. Mason et al, Eds, Oxford University Press:306-307)

Anti-CD207 antibody (Alexa-fluor 647)
STJ170016	St John's Laboratory	100 µg	EUR 393
Description: Langerin/CD207 is a transmembrane C-type lectin receptor (CLR) of epidermal and mucosal Langerhans cells (LCs) that induces Birbeck's granule formation. Langerin features a single carbohydrate recognition domain (CRD) with mannose-type specificity in its extracellular portion. Langerin is unique among the CLRs in that it contains an intracellular domain with a proline-rich motif. Langerin expression has not been reported outside the DC system. (Valladeau J et al, 1999, Eur.J.Immunol., 29:2695-2704; Valladeau J et al, 2000 Immunity, 12 : 71-81; Kashihara M et al, 1986, J.Invest.Derm., 87 :602-607 Ito T et al, 1999, J.Immunol., 163 :1409-1419 ;Saeland S & Valladeau J, CD207 (Langerin) Workshop reports 2002, Leukocyte-Typing VII, White Cell Diff Antigens, D. Mason et al, Eds, Oxford University Press:306-307)

Anti-IL7R antibody (Alexa-fluor 488)
STJ170020	St John's Laboratory	100 µg	EUR 393
Description: The IL7-R consists of 2 chains, IL-7R known as CD127 and common cytokine receptor chain known as CD132. A 75 to 80kDa human IL-7 receptor has been cloned that belongs to hematopoietic cytokinereceptor super family. R34-34, raised against human leukemic pre-B cells, recognized a molecule expressed on normal B cell precursors but not on mature B cells. This antibody specifically reverted IL-7 mediated growth inhibition of leukemic BCP (normal B cells precursors) and mature T cells. IL-7R expression is dramatically influenced by cytokines and antigens. This IL-7R displays both high and low affinity for its ligand (IL-7). Inhibitory and proliferative effects of IL-7 can be mediated through the same receptor on various lineages. CD4+ memory T cells express high level of IL-7R Subsets that express it generally require it, including progenitors of T and B cells, naïve and memory T cells. (Pandrau-Garcia D et al, 1994, Blood, 83, 3613-9 Mazzucchelli R et al, Nat. Review Immunol., 2007,7, 144-54)

Anti-IL7R antibody (Alexa-fluor 546)
STJ170021	St John's Laboratory	100 µg	EUR 393
Description: The IL7-R consists of 2 chains, IL-7R known as CD127 and common cytokine receptor chain known as CD132. A 75 to 80kDa human IL-7 receptor has been cloned that belongs to hematopoietic cytokinereceptor super family. R34-34, raised against human leukemic pre-B cells, recognized a molecule expressed on normal B cell precursors but not on mature B cells. This antibody specifically reverted IL-7 mediated growth inhibition of leukemic BCP (normal B cells precursors) and mature T cells. IL-7R expression is dramatically influenced by cytokines and antigens. This IL-7R displays both high and low affinity for its ligand (IL-7). Inhibitory and proliferative effects of IL-7 can be mediated through the same receptor on various lineages. CD4+ memory T cells express high level of IL-7R Subsets that express it generally require it, including progenitors of T and B cells, naïve and memory T cells. (Pandrau-Garcia D et al, 1994, Blood, 83, 3613-9 Mazzucchelli R et al, Nat. Review Immunol., 2007,7, 144-54)

Anti-IL7R antibody (Alexa-fluor 647)
STJ170022	St John's Laboratory	100 µg	EUR 393
Description: The IL7-R consists of 2 chains, IL-7R known as CD127 and common cytokine receptor chain known as CD132. A 75 to 80kDa human IL-7 receptor has been cloned that belongs to hematopoietic cytokinereceptor super family. R34-34, raised against human leukemic pre-B cells, recognized a molecule expressed on normal B cell precursors but not on mature B cells. This antibody specifically reverted IL-7 mediated growth inhibition of leukemic BCP (normal B cells precursors) and mature T cells. IL-7R expression is dramatically influenced by cytokines and antigens. This IL-7R displays both high and low affinity for its ligand (IL-7). Inhibitory and proliferative effects of IL-7 can be mediated through the same receptor on various lineages. CD4+ memory T cells express high level of IL-7R Subsets that express it generally require it, including progenitors of T and B cells, naïve and memory T cells. (Pandrau-Garcia D et al, 1994, Blood, 83, 3613-9 Mazzucchelli R et al, Nat. Review Immunol., 2007,7, 144-54)

Anti-Hu CD16 Alexa Fluor® 488
A4-646-T100	ExBio	100 tests	EUR 269

Goat anti Mouse IgG1 (Alexa Fluor 488)
43R-1649	Fitzgerald	500 ug	EUR 570
Description: Goat anti Mouse IgG1 secondary antibody (Alexa Fluor 488)

Alpha Fluor™ 532 acid [equivalent to Alexa Fluor™ 532 acid]
1795	AAT Bioquest	10 mg	EUR 393

Mouse IgG1-Alexa 555 conjugate (isotype control)
20102-101-A555	Alpha Diagnostics	50 Tests	EUR 263

Anti-Hu CD72 Alexa Fluor® 488
A4-310-T100	ExBio	100 tests	EUR 269

Anti-Bov CD9 Alexa Fluor® 488
A4-354-C100	ExBio	0.1 mg	EUR 269

Anti-Hu CD30 Alexa Fluor® 700
A7-455-T100	ExBio	100 tests	EUR 269

Anti-Hu CD94 Alexa Fluor® 700
A7-727-T100	ExBio	100 tests	EUR 269

Anti-Hu CD56 Alexa Fluor® 700
A7-789-T100	ExBio	100 tests	EUR 269

AF350-streptavidin conjugate [Streptavidin, Alexa Fluor™ 350 Conjugate]
16890	AAT Bioquest	1 mg	EUR 176

AF488-streptavidin conjugate [Streptavidin, Alexa Fluor™ 488 Conjugate]
16891	AAT Bioquest	1 mg	EUR 176

AF594-streptavidin conjugate [Streptavidin, Alexa Fluor™ 594 Conjugate]
16892	AAT Bioquest	1 mg	EUR 176

AF350 Phalloidin [equivalent to Alexa Fluor® 350 phalloidin]
23150	AAT Bioquest	300 Tests	EUR 306

AF488 Phalloidin [equivalent to Alexa Fluor® 488 phalloidin]
23153	AAT Bioquest	300 Tests	EUR 306

AF594 Phalloidin [equivalent to Alexa Fluor® 594 phalloidin]
23158	AAT Bioquest	300 Tests	EUR 306

Donkey anti Goat IgG (H + L) (Alexa Fluor 594)
43R-ID005AF	Fitzgerald	500 ug	EUR 338
Description: Donkey anti Goat IgG (H + L) secondary antibody (Alexa Fluor 594)

Donkey anti Rat IgG (H + L) (Alexa Fluor 594)
43R-ID022AF	Fitzgerald	500 ug	EUR 364
Description: Donkey anti Rat IgG (H + L) secondary antibody (Alexa Fluor 594)

Donkey anti Goat IgG (H + L) (Alexa Fluor 647)
43R-ID028AF	Fitzgerald	500 ug	EUR 430
Description: Donkey anti Goat IgG (H + L) secondary antibody (Alexa Fluor 647)

Donkey anti Rat IgG (H + L) (Alexa Fluor 594)
43R-ID047AF	Fitzgerald	500 ug	EUR 462
Description: Donkey anti Rat IgG (H + L) secondary antibody (Alexa Fluor 594)

Donkey anti Chicken IgY (H + L) (Alexa Fluor 594)
43R-ID056AF	Fitzgerald	500 ug	EUR 343
Description: Donkey anti Chicken IgY secondary antibody (H + L) (Alexa Fluor 594)

Donkey anti Chicken IgY (H + L) (Alexa Fluor 647)
43R-ID060AF	Fitzgerald	300 ug	EUR 425
Description: Donkey anti Chicken IgY (H + L) (Fab'2) (Alexa Fluor 647)

Rabbit anti Chicken IgY (H + L) (Alexa Fluor 594)
43R-IR016AF	Fitzgerald	1 mg	EUR 281
Description: Rabbit anti Chicken IgY (H + L) secondary antibody (Alexa Fluor 594)

Goat Anti-Mouse IgG(H+L) Alexa Fluor 594–conjugated
S0005	Affbiotech	200ul	EUR 376

Goat Anti-Rabbit IgG(H+L) Alexa Fluor 594–conjugated
S0006	Affbiotech	200ul	EUR 376

Goat Anti-Rabbit IgG(H+L) Alexa Fluor 647–conjugated
S0013	Affbiotech	200ul	EUR 304

Goat Anti-Mouse IgG(H+L) Alexa Fluor 647–conjugated
S0014	Affbiotech	200ul	EUR 304

Goat Anti-Mouse IgG(H+L) Alexa Fluor 488–conjugated
S0017	Affbiotech	200ul	EUR 304

Goat Anti-Rabbit IgG(H+L) Alexa Fluor 488–conjugated
S0018	Affbiotech	200ul	EUR 304

Anti-Hu CD3 zeta (pY153) Alexa Fluor® 488
A4-686-C100	ExBio	0.1 mg	EUR 269

Anti-Hu CD3 zeta (pY72) Alexa Fluor® 488
A4-712-C100	ExBio	0.1 mg	EUR 269

Anti-Hu CD3 zeta (pY142) Alexa Fluor® 488
A4-730-C100	ExBio	0.1 mg	EUR 269

Anti-Hu CD3 zeta (pY111) Alexa Fluor® 488
A4-737-C100	ExBio	0.1 mg	EUR 269

Anti-Hu CD3 zeta (pY153) Alexa Fluor® 647
A6-686-C100	ExBio	0.1 mg	EUR 269

Anti-Hu CD3 zeta (pY72) Alexa Fluor® 647
A6-712-C100	ExBio	0.1 mg	EUR 269

Anti-Hu CD3 zeta (pY142) Alexa Fluor® 647
A6-730-C100	ExBio	0.1 mg	EUR 269

Anti-Hu CD3 zeta (pY111) Alexa Fluor® 647
A6-737-C100	ExBio	0.1 mg	EUR 269

Donkey Anti-Goat IgG (H+L), Alexa Fluor® 594 Conjugated
Ab8011-001	GenDepot	1mg	EUR 334

Donkey Anti-Rabbit IgG (H+L), Alexa Fluor® 488 Conjugated
Ab8032-001	GenDepot	0.5mg	EUR 435

Donkey anti Goat IgG (H + L) (Fab 2) (Alexa Fluor 594)
43R-ID012AF	Fitzgerald	300 ug	EUR 410
Description: Donkey anti Goat IgG (H + L) secondary antibody (Fab'2) (Alexa Fluor 594)

Anti-LAMP3 (human) Monoclonal Antibody (104G4) (Alexa Fluor® 488)
M09406	BosterBio	100ug	EUR 565
Description: Mouse Monoclonal LAMP3 (human) Antibody (104G4) (Alexa Fluor® 488). Validated in IHC and tested in Human.

Anti-Langerin (human) Monoclonal Antibody (DCGM4/122D5) (Alexa Fluor® 488)
M02316	BosterBio	100ug	EUR 580
Description: Mouse Monoclonal Langerin (human) Antibody (DCGM4/122D5) (Alexa Fluor® 488). Validated in IHC and tested in Human.

Rabbit Anti-Rat IgG (H+L)-Alexa 488 Fluor conjugate (adsorbed with human IgG)
50336	Alpha Diagnostics	0.5 ml	EUR 225

Rabbit Anti-Rat IgG (H+L)-Alexa 594 Fluor conjugate (adsorbed with human IgG)
50337	Alpha Diagnostics	0.5 ml	EUR 225

AG 555
HY-15336	MedChemExpress	10mM/1mL	EUR 126

AG 555
B6377-10	ApexBio	10 mg	EUR 144
Description: AG 555 is a potent and selective inhibitor of EGFR with IC50 value of 0.7 ?M. The epidermal growth factor receptor (EGFR) is the cell-surface receptor for epidermal growth factor and plays an important role in tumor invasion and cancer cell proliferation.

AG 555
B6377-25	ApexBio	25 mg	EUR 276
Description: AG 555 is a potent and selective inhibitor of EGFR with IC50 value of 0.7 ?M. The epidermal growth factor receptor (EGFR) is the cell-surface receptor for epidermal growth factor and plays an important role in tumor invasion and cancer cell proliferation.

AG 555
B6377-50	ApexBio	50 mg	EUR 447
Description: AG 555 is a potent and selective inhibitor of EGFR with IC50 value of 0.7 ?M. The epidermal growth factor receptor (EGFR) is the cell-surface receptor for epidermal growth factor and plays an important role in tumor invasion and cancer cell proliferation.

MCC-555
C4892-1	ApexBio	1 mg	EUR 158
Description: MCC-555, also known as RWJ-241947, is a novel peroxisome proliferator?activated receptor ? ligand [1]. The PPAR? receptors mainly express in adipose tissue, colon and macrophages involved in regulating fatty acid storage and glucose metabolism.

MCC-555
C4892-10	ApexBio	10 mg	EUR 918
Description: MCC-555, also known as RWJ-241947, is a novel peroxisome proliferator?activated receptor ? ligand [1]. The PPAR? receptors mainly express in adipose tissue, colon and macrophages involved in regulating fatty acid storage and glucose metabolism.

MCC-555
C4892-5	ApexBio	5 mg	EUR 538
Description: MCC-555, also known as RWJ-241947, is a novel peroxisome proliferator?activated receptor ? ligand [1]. The PPAR? receptors mainly express in adipose tissue, colon and macrophages involved in regulating fatty acid storage and glucose metabolism.

Alpha Fluor™ 488 amine
1705	AAT Bioquest	1 mg	EUR 306

Alpha Fluor™ 488 Hydroxylamine
1900	AAT Bioquest	1 mg	EUR 306

Tide Fluor 2-LL-37
H-8286.0100	Bachem	0.1mg	EUR 312
Description: Sum Formula: C205H340N60O53+dye

Tide Fluor 2-LL-37
H-8286.0500	Bachem	0.5mg	EUR 1017
Description: Sum Formula: C205H340N60O53+dye

Recombinant (E.Coli, His-tag) HIV-1 pol Integrase
RP-555	Alpha Diagnostics	10 ug	EUR 164

IL12 B Recombinant Protein
96-555	ProSci	0.02 mg	EUR 390.5
Description: Interleukin-12 (IL12) is also known as natural killer cell stimulatory factor (NKSF), cytotoxic lymphocyte maturation factor (CLMF) , is a heterodimeric cytokine encoded by two separate genes, IL-12A (p35) and IL-12B (p40). IL12 is naturally produced by dendritic cells, macrophages and human B-lymphoblastoid cells (NC-37) in response to antigenic stimulation. IL-12 is involved in the differentiation of naive T cells into Th0 cells and plays an important role in the activities of natural killer cells and T lymphocytes.IL-12 also has anti-angiogenic activity, which means it can block the formation of new blood vessels.Interleukin-12 subunit beta (IL12B) also known as NKSF2, CLMF2 and P40. Interleukin-12 subunit beta has been shown to interact with IL23. A large excess of monomeric IL12B is also secreted by the cells producing IL12, and exhibits no demonstrable biological activity. Overexpression of IL12B gene has been shown to be associated with the pathogenesis of multiple sclerosis. In addition, studies have revealed that the promoter polymorphism of this gene is implicated in the severity of atopic and non-atopic asthma in children.

Influenza A (Swine H1N1) Hemagglutinin (A/California/14/2009) Peptide
11-555	ProSci	0.05 mg	EUR 527
Description: Influenza A (Swine H1N1) Hemagglutinin (A/California/14/2009) Peptide

G-CSF Recombinant Protein
40-555	ProSci	0.01 mg	EUR 401
Description: G-CSF is a hematopoietic growth factor that stimulates the development of committed progenitor cells to neutrophils and enhances the functional activities of the mature end-cell. It is produced in response to specific stimulation by a variety of cells including macrophages, fibroblasts, endothelial cells and bone marrow stroma. G-CSF is being used clinically to facilitate hematopoietic recovery after bone marrow transplantation. Human and murine G-CSF are cross-species reactive. Recombinant human G-CSF is an 18.7 kDa protein consisting of 174 amino acid residues.

IL-10 Recombinant Protein
90-555	ProSci	10 ug	EUR 416.75
Description: Interleukin-10 (IL-10) is a cytokine produced by activated Th2 cells, B cells, keratinocytes and monocytes/macrophages. In vitro murine and human IL-10 inhibits cytokine synthesis by Th1 cells, natural killer cells and monocytes/macrophages. Several studies have suggested the potential application of IL-10 as an anti-inflammatory agent in the treatment of septic shock and as an immunosuppressive agent in certain T cell mediated autoimmune diseases.

Vanin-2 Recombinant Protein
91-555	ProSci	0.05 mg	EUR 542.75
Description: Vascular Non-Inflammatory Molecule 2 (VNN2) is a member of the CN hydrolase family. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. they possess pantetheinase activity, which may play a role in oxidative-stress response. VNN2 is a GPI-anchored cell surface molecule that plays a role in transendothelial migration of neutrophils. VNN2 involved in the thymus homing of bone marrow cells. In addition, VNN2 may regulate beta-2 integrin-mediated cell adhesion, migration and motility of neutrophil.

OX40 Recombinant Protein
92-555	ProSci	0.05 mg	EUR 448.25
Description: OX40, also termed CD134 and TNFRSF4, is a T cell co-stimulatory molecule of the TNF receptor superfamily which plays a key role in the survival and homeostasis of effector and memory T cells. OX40 is expressed on CD4+ and CD8+ T cells upon engagement of the TCR by antigen presenting cells along with co-stimulation by CD40-CD40 Ligand and CD28-B7. The interaction between OX40 and OX40 ligand (OX40L) will occur when activated T cells bind to professional antigen-presenting cells (APCs). The T-cell functions, including cytokine production, expansion, and survival, are then enhanced by the OX40 costimulatory signals. OX40 signals are critical for controlling the function and differentiation of Foxp3+ regulatory T cells. OX40-OX40L interaction regulates T-cell tolerance, peripheral T-cell homeostasis, and T-cell-mediated inflammatory diseases.

Anti-Cytokeratins Alexa Fluor488
A4-108-C025	ExBio	0.025 mg	EUR 175

Anti-Cytokeratins Alexa Fluor488
A4-108-C100	ExBio	0.1 mg	EUR 310

Anti-PSMA Alexa Fluor488
A4-539-C025	ExBio	0.025 mg	EUR 227

Anti-PSMA Alexa Fluor488
A4-539-C100	ExBio	0.1 mg	EUR 414

Anti-FoxP3 Alexa Fluor488
A4-601-C025	ExBio	0.025 mg	EUR 201

Anti-FoxP3 Alexa Fluor488
A4-601-C100	ExBio	0.1 mg	EUR 362

Anti-Phosphotyrosine Alexa Fluor647
A6-263-C025	ExBio	0.025 mg	EUR 154

Anti-Phosphotyrosine Alexa Fluor647
A6-263-C100	ExBio	0.1 mg	EUR 269

Anti-LCK Alexa Fluor647
A6-269-C025	ExBio	0.025 mg	EUR 206

Anti-LCK Alexa Fluor647
A6-269-C100	ExBio	0.1 mg	EUR 373

Anti-FoxP3 Alexa Fluor647
A6-601-C025	ExBio	0.025 mg	EUR 201

Anti-FoxP3 Alexa Fluor647
A6-601-C100	ExBio	0.1 mg	EUR 362

CellBrite Fix 555
30088	Biotium	1KIT	EUR 563
Description: Minimum order quantity: 1 unit of 1KIT

Cyanine 555 alkyne
92100	Biotium	1MG	EUR 226
Description: Minimum order quantity: 1 unit of 1MG

Cyanine 555 aminooxy
96009	Biotium	1MG	EUR 342
Description: Minimum order quantity: 1 unit of 1MG

Cyanine 555 tyramide
96020	Biotium	0.5mg	EUR 353
Description: Minimum order quantity: 1 unit of 0.5mg

Monoclonal Anti-Monkey IgG-Alexa 555 Conj. (specific for monkey; no reactivity with human or animals IgG)
70030-AF555	Alpha Diagnostics	50 tests	EUR 347

Alpha Fluor™ 488 NHS Ester
1812	AAT Bioquest	1 mg	EUR 219

Alpha Fluor™ 532 NHS Ester
1819	AAT Bioquest	1 mg	EUR 219

Alpha Fluor™ 594 C5 Maleimide
1891	AAT Bioquest	1 mg	EUR 219

Metal Fluor™ Zn-520, AM
21263	AAT Bioquest	1 mg	EUR 219

Pattern variability is assessed by learning tissue phantoms much like these used within the experimental verification of the approach and which can be consultant of (irregular) dental tissues. For tissue characterization, good restoration of the built-in attenuation ensues by using spatially compact radiation sources. For tissue imaging, spatially prolonged sources with broad bandwidth are superior because of the implicit longitudinal coherence filter. For each functions, pattern variability points could also be neutralized by allowing spatial divergence of scattered photons.