An efficient proteomics method to identify the cellular targets of protein kinase inhibitors.

An efficient proteomics method to identify the cellular targets of protein kinase inhibitors.

Small molecule inhibitors of protein kinases are extensively utilized in sign transduction analysis and are rising as a significant class of medication. Though interpretation of organic outcomes obtained with these reagents critically is determined by their selectivity, environment friendly strategies for proteome-wide evaluation of kinase inhibitor selectivity haven’t but been reported.
Right here, we handle this vital problem and describe a way for figuring out targets of the extensively used p38 kinase inhibitor SB 203580. Immobilization of an acceptable SB 203580 analogue and totally optimized biochemical situations for affinity chromatography permitted the dramatic enrichment and identification of a number of beforehand unknown protein kinase targets of SB 203580.
In vitro kinase assays confirmed that cyclin G-associated kinase (GAK) and CK1 have been nearly as potently inhibited as p38alpha whereas RICK [Rip-like interacting caspase-like apoptosis-regulatory protein (CLARP) kinase/Rip2/CARDIAK] was much more delicate to inhibition by SB 203580. The mobile kinase exercise of RICK, a recognized sign transducer of inflammatory responses, was already inhibited by submicromolar concentrations of SB 203580 in intact cells.
Due to this fact, our outcomes warrant a reevaluation of the huge quantity of knowledge obtained with SB 203580 and may need important implications on the event of p38 inhibitors as antiinflammatory medicine. Primarily based on the procedures described right here, environment friendly affinity purification methods might be developed for different protein kinase inhibitors, offering essential details about their mobile modes of motion.
The immunological processes concerned within the collaborative defence of organisms are affected by dietary standing. Thus, a optimistic continual imbalance between power consumption and expenditure results in conditions of weight problems, which can affect unspecific and particular immune responses mediated by humoral and cell mediated mechanisms.
Moreover, a number of traces of proof have supported a hyperlink between adipose tissue and immunocompetent cells. This interplay is illustrated in weight problems, the place extra adiposity and impaired immune perform have been described in each people and genetically overweight rodents.
Nevertheless, restricted and sometimes controversial info exist evaluating immunity in overweight and non-obese topics in addition to concerning the mobile and molecular mechanisms implicated. Normally phrases, scientific and epidemiological knowledge assist the proof that the incidence and severity of particular forms of infectious diseases are increased in overweight individuals as in comparison with lean people along with the incidence of poor antibody responses to antigens in obese topics.
Leptin would possibly play a key function in linking dietary standing with T-cell perform. The complexities and heterogeneity of the host defences in regards to the immune response in several dietary circumstances affecting the power steadiness require an integral examine of the immunocompetent cells, their subsets and merchandise in addition to particular and unspecific inducer/regulator techniques. On this context, extra analysis is required to make clear the scientific implications of the alterations induced by weight problems on the immune perform.

Runx1 is required for zebrafish blood and vessel growth and expression of a human RUNX1-CBF2T1 transgene advances a mannequin for research of leukemogenesis.

RUNX1/AML1/CBFA2 is important for definitive hematopoiesis, and chromosomal translocations affecting RUNX1 are incessantly concerned in human leukemias. Consequently, the traditional perform of RUNX1 and its involvement in leukemogenesis stay topic to intensive analysis.
To additional elucidate the function of RUNX1 in hematopoiesis, we cloned the zebrafish ortholog (runx1) and analyzed its perform utilizing this mannequin system. Zebrafish runx1 is expressed in hematopoietic and neuronal cells throughout early embryogenesis. runx1 expression within the lateral plate mesoderm co-localizes with the hematopoietic transcription issue scl, and expression of runx1 is markedly diminished within the zebrafish mutants spadetail and cloche.
Transient expression of runx1 in cloche embryos resulted in partial rescue of the hematopoietic defect. Depletion of Runx1 with antisense morpholino oligonucleotides abrogated the event of each blood and vessels, as demonstrated by lack of circulation, incomplete growth of vasculature and the buildup of immature hematopoietic precursors.
The block in definitive hematopoiesis is just like that noticed in Runx1 knockout mice, implying that zebrafish Runx1 has a perform equal to that in mammals. Our knowledge counsel that zebrafish Runx1 capabilities in each blood and vessel growth on the hemangioblast degree, and contributes to each primitive and definitive hematopoiesis. Depletion of Runx1 additionally induced aberrant axonogenesis and irregular distribution of Rohon-Beard cells, offering the primary practical proof of a task for vertebrate Runx1 in neuropoiesis.
To offer a base for analyzing the function of Runx1 in leukemogenesis, we investigated the results of transient expression of a human RUNX1-CBF2T1 transgene [product of the t(8;21) translocation in acute myeloid leukemia] in zebrafish embryos.
Expression of RUNX1-CBF2T1 induced disruption of regular hematopoiesis, aberrant circulation, inside hemorrhages and mobile dysplasia. These defects reproduce these noticed in Runx1-depleted zebrafish embryos and RUNX1-CBF2T1 knock-in mice. The phenotype obtained with transient expression of RUNX1-CBF2T1 validates the zebrafish as a mannequin system to check t(8;21)-mediated leukemogenesis.

From in vivo to in silico biology and again.

The large acquisition of knowledge in molecular and mobile biology has led to the renaissance of an outdated matter: simulations of organic techniques. Simulations, more and more paired with experiments, are being efficiently and routinely utilized by computational biologists to know and predict the quantitative behaviour of complicated techniques, and to drive new experiments.
However, many experimentalists nonetheless think about simulations an esoteric self-discipline just for initiates. Suspicion in the direction of simulations ought to dissipate as the restrictions and benefits of their utility are higher appreciated, opening the door to their everlasting adoption in on a regular basis analysis.

Proteome-wide evaluation of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.

Submit-translational modification of proteins by lysine acetylation performs vital regulatory roles in residing cells. The budding yeast Saccharomyces cerevisiae is a extensively used unimobile eukaryotic mannequin organism in biomedical analysis.
S. cerevisiae accommodates a number of evolutionary conserved lysine acetyltransferases and deacetylases. Nevertheless, just a few dozen acetylation websites in S. cerevisiae are recognized, presenting a significant impediment for additional understanding the regulatory roles of acetylation on this organism.
An efficient proteomics method to identify the cellular targets of protein kinase inhibitors.
Right here we use excessive decision mass spectrometry to determine about 4000 lysine acetylation websites in S. cerevisiae. Acetylated proteins are implicated within the regulation of numerous cytoplasmic and nuclear processes together with chromatin group, mitochondrial metabolism, and protein synthesis.
Bioinformatic evaluation of yeast acetylation websites reveals that acetylated lysines are considerably extra conserved in contrast with nonacetylated lysines. A big fraction of the conserved acetylation websites are current on proteins concerned in mobile metabolism, protein synthesis, and protein folding. Moreover, quantification of the Rpd3-regulated acetylation websites recognized a number of beforehand recognized, in addition to new putative substrates of this deacetylase.

anti-Superoxide Dismutase 2

LF-PA0021 100 ul
EUR 334
Description: Rabbit polyclonal to Superoxide Dismutase 2

anti-Superoxide Dismutase 2

LF-PA10015 50 ug
EUR 363
Description: Mouse polyclonal to Superoxide Dismutase 2

anti-Superoxide Dismutase 4

YF-PA16619 50 ul
EUR 363
Description: Mouse polyclonal to Superoxide Dismutase 4

anti-Superoxide Dismutase 4

YF-PA16620 50 ug
EUR 363
Description: Mouse polyclonal to Superoxide Dismutase 4

anti-Superoxide Dismutase 4

YF-PA16621 100 ul
EUR 403
Description: Rabbit polyclonal to Superoxide Dismutase 4

anti-Superoxide Dismutase 4

YF-PA16622 100 ug
EUR 403
Description: Rabbit polyclonal to Superoxide Dismutase 4

anti-Superoxide Dismutase 1

YF-PA14732 50 ug
EUR 363
Description: Mouse polyclonal to Superoxide Dismutase 1

anti-Superoxide Dismutase 1

YF-PA14733 100 ug
EUR 403
Description: Rabbit polyclonal to Superoxide Dismutase 1

anti-Superoxide Dismutase 2

YF-PA14735 50 ul
EUR 363
Description: Mouse polyclonal to Superoxide Dismutase 2

anti-Superoxide Dismutase 2

YF-PA14737 100 ug
EUR 403
Description: Rabbit polyclonal to Superoxide Dismutase 2

anti-Superoxide Dismutase 4

YF-PA25443 50 ul
EUR 334
Description: Mouse polyclonal to Superoxide Dismutase 4

Superoxide dismutase

44R-1105 1 MU
EUR 1429
Description: Superoxide dismutase enzyme

Anti-Superoxide Dismutase 3/SOD3 Antibody

A01784-1 100ug/vial
EUR 334

Anti-Superoxide Dismutase 3/SOD3 Antibody

PA1899 100ug/vial
EUR 334

Anti-Superoxide Dismutase 3/SOD3 Antibody

PB9747 100ug/vial
EUR 334

Superoxide Dismutase 3 antibody

10R-7477 100 ul
EUR 393
Description: Mouse monoclonal Superoxide Dismutase 3 antibody

Superoxide Dismutase 3, mouse

LF-P0418 0.5mg
EUR 303
Description: Superoxide Dismutase 3, mouse protein

anti-Superoxide Dismutase 4 (2A1)

LF-MA0016 100 ul
EUR 334
Description: Mouse monoclonal to Superoxide Dismutase 4

anti-Superoxide Dismutase 4 (11G1)

LF-MA0019 100 ul
EUR 334
Description: Mouse monoclonal to Superoxide Dismutase 4

anti-Superoxide Dismutase 1 (72B1)

LF-MA0023 100 ul
EUR 334
Description: Mouse monoclonal to Superoxide Dismutase 1

anti-Superoxide Dismutase 1 (8A1)

LF-MA0029 100 ul
EUR 334
Description: Mouse monoclonal to Superoxide Dismutase 1

anti-Superoxide Dismutase 2 (2A1)

LF-MA0030 100 ul
EUR 334
Description: Mouse monoclonal to Superoxide Dismutase 2

anti-Superoxide Dismutase 2 (1E8)

LF-MA0035 100 ul
EUR 334
Description: Mouse monoclonal to Superoxide Dismutase 2

anti-Superoxide Dismutase 4 (3A1)

LF-MA0042 100 ul
EUR 334
Description: Mouse monoclonal to Superoxide Dismutase 4

Superoxide Dismutase protein

30R-2714 100 ug
EUR 452
Description: Purified recombinant Human Superoxide Dismutase protein

Superoxide Dismutase Antibody

abx022850-1ml 1 ml
EUR 878
  • Shipped within 5-10 working days.

Superoxide Dismutase Antibody

abx021109-1mg 1 mg
EUR 926
  • Shipped within 5-10 working days.

Anti-Superoxide Dismutase 4/CCS Antibody

A00314-1 100ug/vial
EUR 334

Anti-Superoxide Dismutase 1/SOD1 Antibody

PA1345 100ug/vial
EUR 334

Anti-Superoxide Dismutase 1/SOD1 Antibody

PB9402 100ug/vial
EUR 334

Rabbit Anti-human Superoxide Dismutase 3 (SOD3) IgG

SOD32-A 100 ug
EUR 482

Polyclonal Goat anti-GST p-form

GST-ANTI-3 50 uL
EUR 280

Recombinant Human Superoxide Dismutase

7-06472 20µg Ask for price

Recombinant Human Superoxide Dismutase

7-06473 100µg Ask for price

Recombinant Human Superoxide Dismutase

7-06474 1mg Ask for price

Recombinant E.Coli Superoxide Dismutase

7-06481 5µg Ask for price

Recombinant E.Coli Superoxide Dismutase

7-06482 20µg Ask for price

Recombinant E.Coli Superoxide Dismutase

7-06483 1mg Ask for price

Superoxide Dismutase 2 antibody

10R-7478 100 ul
EUR 393
Description: Mouse monoclonal Superoxide Dismutase 2 antibody

Superoxide Dismutase 2 antibody

10R-7479 100 ul
EUR 393
Description: Mouse monoclonal Superoxide Dismutase 2 antibody

Superoxide Dismutase 1 antibody

10R-7482 100 ul
EUR 393
Description: Mouse monoclonal Superoxide Dismutase 1 antibody

Superoxide Dismutase 1 antibody

10R-7483 100 ul
EUR 393
Description: Mouse monoclonal Superoxide Dismutase 1 antibody

Superoxide Dismutase 4 antibody

10R-7484 100 ul
EUR 393
Description: Mouse monoclonal Superoxide Dismutase 4 antibody

Superoxide Dismutase 4 antibody

10R-7485 100 ul
EUR 393
Description: Mouse monoclonal Superoxide Dismutase 4 antibody

Superoxide Dismutase 1 Antibody

49350-100ul 100ul
EUR 333

Superoxide Dismutase 1 Antibody

49350-50ul 50ul
EUR 239

Superoxide Dismutase Assay Kit

abx096009-100Assays 100 Assays
EUR 472
  • Shipped within 5-10 working days.

Superoxide Dismutase Standard, 1EA

C098-1EA 1EA
EUR 143

Superoxide Dismutase (SOD1) Antibody

abx414380-01mg 0.1 mg
EUR 439
  • Shipped within 1 week.

Superoxide Dismutase 1, Human

LF-P0010 0.5 mg
EUR 202
Description: Superoxide Dismutase 1, Human protein

Superoxide Dismutase 2, Human

LF-P0013 0.5 mg
EUR 202
Description: Superoxide Dismutase 2, Human protein

Superoxide Dismutase 4, Human

LF-P0020 0.5 mg
EUR 202
Description: Superoxide Dismutase 4, Human protein

Superoxide Dismutase 4, mouse

LF-P0410 0.5 mg
EUR 303
Description: Superoxide Dismutase 4, mouse protein

Native Bovine Superoxide Dismutase

NATE-0675 125mg
EUR 270

Mn-Superoxide Dismutase, Recombinant

NATE-1142 10mg
EUR 594

Native Plant Superoxide Dismutase

NATE-1619 1g
EUR 270

Chicken Superoxide Dismutase (SOD)

QY-E80142 96T
EUR 426

SOD, Superoxide Dismutase, human

RC512-12 20ug
EUR 104.38
  • Product category: Proteins/Recombinant Proteins/Enzymes

Superoxide Dismutase 3, Extracellular (SOD3) Antibody

20-abx005295
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul
  • Shipped within 5-10 working days.

Superoxide Dismutase 3, Extracellular (SOD3) Antibody

20-abx178501
  • EUR 1135.00
  • EUR 551.00
  • 1 mg
  • 200 ug
  • Please enquire.

Superoxide Dismutase 3, Extracellular (SOD3) Antibody

20-abx218694
  • EUR 425.00
  • EUR 342.00
  • 100 ug
  • 50 ug
  • Shipped within 5-10 working days.

Superoxide Dismutase 3, Extracellular (SOD3) Antibody

20-abx103950
  • EUR 398.00
  • EUR 133.00
  • EUR 1107.00
  • EUR 537.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Superoxide Dismutase 3, Extracellular (SOD3) Antibody

20-abx103951
  • EUR 411.00
  • EUR 133.00
  • EUR 1135.00
  • EUR 551.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Superoxide Dismutase 3, Extracellular (SOD3) Antibody

20-abx103952
  • EUR 300.00
  • EUR 133.00
  • EUR 801.00
  • EUR 425.00
  • EUR 258.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Superoxide Dismutase 3, Extracellular (SOD3) Antibody

20-abx115903
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul
  • Shipped within 5-10 working days.

Superoxide Dismutase 3, Extracellular (SOD3) Antibody

20-abx129985
  • EUR 425.00
  • EUR 133.00
  • EUR 1177.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Superoxide Dismutase 3, Extracellular (SOD3) Antibody

20-abx174663
  • EUR 314.00
  • EUR 787.00
  • EUR 411.00
  • EUR 154.00
  • EUR 258.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-12 working days.

Superoxide Dismutase 3, Extracellular (SOD3) Antibody

20-abx174664
  • EUR 843.00
  • EUR 439.00
  • 1 mg
  • 200 ug
  • Please enquire.

Superoxide Dismutase 3, Extracellular (SOD3) Antibody

20-abx174665
  • EUR 843.00
  • EUR 439.00
  • 1 mg
  • 200 ug
  • Please enquire.

Superoxide Dismutase 3, Extracellular (SOD3) Antibody

abx033034-400ul 400 ul
EUR 523
  • Shipped within 5-10 working days.

Superoxide Dismutase 3, Extracellular (SOD3) Antibody

abx033034-80l 80 µl
EUR 286
  • Shipped within 5-10 working days.

Superoxide Dismutase 3, Extracellular (SOD3) Antibody

abx238105-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

Superoxide Dismutase 3, Extracellular (SOD3) Antibody

20-abx320304
  • EUR 300.00
  • EUR 244.00
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.

Superoxide Dismutase 3, Extracellular (SOD3) Antibody

abx448432-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

Superoxide Dismutase 3, Extracellular (SOD3) Antibody

20-abx305397
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Recombinant Superoxide Dismutase 3, Extracellular (SOD3)

4-RPA117Hu01
  • EUR 320.42
  • EUR 188.00
  • EUR 926.56
  • EUR 375.52
  • EUR 651.04
  • EUR 277.00
  • EUR 2166.40
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: P08294
  • Buffer composition: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 27.9kDa
  • Isoelectric Point: 6.3
Description: Recombinant Human Superoxide Dismutase 3, Extracellular expressed in: E.coli

Recombinant Superoxide Dismutase 3, Extracellular (SOD3)

4-RPA117Mu01
  • EUR 565.92
  • EUR 254.00
  • EUR 1847.20
  • EUR 682.40
  • EUR 1264.80
  • EUR 442.00
  • EUR 4468.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: O09164
  • Buffer composition: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 26.2kDa
  • Isoelectric Point: 6.8
Description: Recombinant Mouse Superoxide Dismutase 3, Extracellular expressed in: E.coli

Recombinant Superoxide Dismutase 3, Extracellular (SOD3)

4-RPA117Ra01
  • EUR 431.52
  • EUR 218.00
  • EUR 1343.20
  • EUR 514.40
  • EUR 928.80
  • EUR 352.00
  • EUR 3208.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: Q08420
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 28.6kDa
  • Isoelectric Point: 6.7
Description: Recombinant Rat Superoxide Dismutase 3, Extracellular expressed in: E.coli

Recombinant Superoxide Dismutase 3, Extracellular (SOD3)

4-RPA117Rb01
  • EUR 510.37
  • EUR 239.00
  • EUR 1638.88
  • EUR 612.96
  • EUR 1125.92
  • EUR 404.00
  • EUR 3947.20
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: P41975
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 19.1kDa
  • Isoelectric Point: Inquire
Description: Recombinant Rabbit Superoxide Dismutase 3, Extracellular expressed in: E.coli

Superoxide Dismutase 3 (SOD-3) Antibody (1H12)

6170-100
EUR 403

Mouse Superoxide Dismutase 3 (SOD3) CLIA Kit

20-abx190563
  • EUR 7973.00
  • EUR 4246.00
  • EUR 981.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Shipped within 5-7 working days.

Rat Superoxide Dismutase 3, Extracellular (SOD3) Protein

20-abx167675
  • EUR 718.00
  • EUR 286.00
  • EUR 2207.00
  • EUR 843.00
  • EUR 509.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Mouse Superoxide Dismutase 3, Extracellular (SOD3) Protein

20-abx069199
  • EUR 787.00
  • EUR 300.00
  • EUR 2486.00
  • EUR 940.00
  • EUR 551.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Rat Superoxide Dismutase 3, Extracellular (SOD3) Protein

20-abx069200
  • EUR 606.00
  • EUR 258.00
  • EUR 1817.00
  • EUR 718.00
  • EUR 439.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Human Superoxide Dismutase 3, Extracellular (SOD3) Protein

20-abx069749
  • EUR 453.00
  • EUR 230.00
  • EUR 1261.00
  • EUR 537.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Superoxide Dismutase 3, Extracellular (SOD3) Antibody (Biotin)

20-abx271786
  • EUR 425.00
  • EUR 230.00
  • EUR 1191.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-15 working days.

Superoxide Dismutase 3, Extracellular (SOD3) Antibody (Biotin)

20-abx272594
  • EUR 425.00
  • EUR 230.00
  • EUR 1219.00
  • EUR 592.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-15 working days.

Superoxide Dismutase 3, Extracellular (SOD3) Antibody Pair

20-abx370059
  • EUR 1622.00
  • EUR 1038.00
  • 10 × 96 tests
  • 5 × 96 tests
  • Shipped within 5-15 working days.

Superoxide Dismutase 3, Extracellular (SOD3) Antibody Pair

20-abx370555
  • EUR 1706.00
  • EUR 1094.00
  • 10 × 96 tests
  • 5 × 96 tests
  • Shipped within 5-15 working days.

Superoxide Dismutase 3, Extracellular (SOD3) Antibody (ALP)

abx442298-100ug 100 ug
EUR 565
  • Shipped within 5-12 working days.

Superoxide Dismutase 3, Extracellular (SOD3) Antibody (APC)

abx442579-100ug 100 ug
EUR 565
  • Shipped within 5-12 working days.

Superoxide Dismutase 3, Extracellular (SOD3) Antibody (Biotin)

abx442860-100ug 100 ug
EUR 565
  • Shipped within 5-12 working days.

Superoxide Dismutase 3, Extracellular (SOD3) Antibody (FITC)

abx443140-100ug 100 ug
EUR 565
  • Shipped within 5-12 working days.

Superoxide Dismutase 3, Extracellular (SOD3) Antibody (HRP)

abx443420-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

Superoxide Dismutase 3, Extracellular (SOD3) Antibody (PerCP)

abx443982-100ug 100 ug
EUR 565
  • Shipped within 5-12 working days.

Superoxide Dismutase 3, Extracellular (SOD3) Antibody (RPE)

abx444263-100ug 100 ug
EUR 565
  • Shipped within 5-12 working days.
Rpd3 deficiency elevated acetylation of the SAGA (Spt-Ada-Gcn5-Acetyltransferase) complicated subunit Sgf73 on Okay33. This acetylation website is situated inside a crucial regulatory area in Sgf73 that interacts with Ubp8 and is concerned within the activation of the Ubp8-containing histone H2B deubiquitylase complicated. Our knowledge supplies the primary world survey of acetylation in budding yeast, and suggests a wide-ranging regulatory scope of this modification. The offered knowledgeset might function an vital useful resource for the practical evaluation of lysine acetylation in eukaryotes.
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