Tumor-shed antigen CA125 blocks complement-mediated killing via suppression of C1q-antibody binding.

Tumor-shed antigen CA125 blocks complement-mediated killing via suppression of C1q-antibody binding.

C1q-engagement with IgG and IgM sort antibodies is the initiating step of classical complement-mediated immunity. The tumor shed antigen CA125 has been reported to have immunosuppressive results on host tumor responses in addition to commercially authorized and experimental monoclonal antibody … Read More

Mass Cytometry: Single Cells, Many Features.

Mass Cytometry: Single Cells, Many Features.

Know-how growth in organic analysis typically goals to both enhance the variety of mobile options that may be surveyed concurrently or improve the decision at which such observations are doable. For many years, stream cytometry has balanced these objectives to fill a vital want … Read More