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Reduced TREM2 activation in microglia of patients with Alzheimer's disease

Reduced TREM2 activation in microglia of patients with Alzheimer’s disease

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Loss-of-function variants of triggering receptor expressed on myeloid cells 2 (TREM2) enhance the chance of creating Alzheimer’s illness (AD). The mechanism via which TREM2 contributes to the illness (TREM2 activation vs inactivation) is basically unknown. Right here, we analyzed adjustments in a gene … Read More

Ameliorative effect of myrcene in mouse model of Alzheimer's disease

Ameliorative effect of myrcene in mouse model of Alzheimer’s disease

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Myrcene (Myr) has been reported to indicate neuroprotective results in cerebral ischemia. On this analysis work, we investigated the Myr impact on neurobehavioural, and neuropathological alteration in mice induced by Aluminium trichloride (AlCl3) and D – galactose. The administration of … Read More