Protection of CTGF Antibody Against Diabetic Nephropathy in Mice Via Reducing Glomerular β-Catenin Expression and Podocyte Epithelial-Mesenchymal Transition.

Protection of CTGF Antibody Against Diabetic Nephropathy in Mice Via Reducing Glomerular β-Catenin Expression and Podocyte Epithelial-Mesenchymal Transition.

Regardless of substantial progress in medical care, the morbidity fee of diabetic nephropathy (DN) stays excessive in sufferers with diabetes. Proof means that connective tissue progress issue (CTGF) induced podocyte harm could contribute to DN and CTGF inhibition might cut back albuminuria. Nonetheless, thus far the mechanisms concerned within the impact of CTGF on podocyte […]