ImmPort: disseminating data to the public for the future of immunology.

The immunology informationbase and evaluation portal (ImmPort) system is the archival repository and dissemination car for scientific and molecular informationunits created by analysis consortia funded by the Nationwide Institute of Allergy and Infectious Illnesses Division of Allergy, Immunology, and Transplantation.
With almost 100 informationunits now publicly out there and lots of of downloads per thirty days, ImmPort is a vital supply for uncooked information and protocols from scientific trials, mechanistic research, and novel strategies for mobile and molecular measurements.
To facilitate information switch, templates for information illustration and customary working procedures have additionally been created and are additionally publicly out there. ImmPort facilitates transparency and reproducibility in immunology analysis, serves as an vital useful resource for training, and allows newly generated hypotheses and information-driven science.

Cognitive management deficits in schizophrenia: mechanisms and that means.

Though schizophrenia is an sickness that has been traditionally characterised by the presence of optimistic symptomatology, a long time of analysis spotlight the significance of cognitive deficits on this dysfunction. This overview proposes that the theoretical mannequin of cognitive management, which is predicated on up to date cognitive neuroscience, supplies a unifying principle for the cognitive and neural abnormalities underlying larger cognitive dysfunction in schizophrenia.
To help this mannequin, we define converging proof from a number of modalities (eg, structural and purposeful neuroimaging, pharmacological information, and animal fashions) and samples (eg, scientific excessive danger, genetic excessive danger, first episode, and power topics) to emphasise how dysfunction in cognitive management mechanisms supported by the prefrontal cortex contribute to the pathophysiology of upper cognitive deficits in schizophrenia.
Our mannequin supplies a theoretical hyperlink between mobile abnormalities (eg, reductions in dentritic spines, interneuronal dysfunction), purposeful disturbances in native circuit perform (eg, gamma abnormalities), altered inter-regional cortical connectivity, a variety of upper cognitive deficits, and symptom presentation (eg, disorganization) within the dysfunction.
Lastly, we talk about current advances within the neuropharmacology of cognition and the way they will inform a focused method to the event of efficient therapies for this disabling side of schizophrenia.
ImmPort: disseminating data to the public for the future of immunology.

Giant-scale serial evaluation of gene expression reveals genes differentially expressed in ovarian most cancers.

Difficulties within the detection, prognosis, and remedy of ovarian most cancers lead to an general low survival price of girls with this illness. A greater understanding of the pathways concerned in ovarian tumorigenesis will doubtless present new targets for early and efficient intervention.
Right here, now we have used serial evaluation of gene expression (SAGE) to generate world gene expression profiles from numerous ovarian cell traces and tissues, together with major cancers, ovarian floor epithelia cells, and cystadenoma cells. The profiles have been used to check general patterns of gene expression and to establish differentially expressed genes.
We’ve got sequenced a complete of 385,000 tags, yielding >56,000 genes expressed in 10 totally different libraries derived from ovarian tissues. On the whole, ovarian most cancers cell traces confirmed comparatively excessive ranges of similarity to libraries from different most cancers cell traces, whatever the tissue of origin (ovarian or colon), indicating that these traces had misplaced lots of their tissue-specific expression patterns.
In distinction, immortalized ovarian floor epithelia and ovarian cystadenoma cells confirmed a lot larger similarity to major ovarian carcinomas than to major colon carcinomas. Major tissue specimens subsequently seemed to be a greater mannequin for gene expression analyses.
Utilizing the expression profiles described above and stringent choice standards, now we have recognized a lot of genes extremely differentially expressed between nontransformed ovarian epithelia and ovarian carcinomas. A number of the genes recognized are already identified to be overexpressed in ovarian most cancers, however a number of signify novel candidates.
Lots of the genes up-regulated in ovarian most cancers signify floor or secreted proteins comparable to claudin-Three and -4, HE4, mucin-1, epithelial mobile adhesion molecule, and mesothelin. Curiously, each apolipoprotein E (ApoE) and ApoJ, two proteins concerned in lipid homeostasis, are among the many genes extremely up-regulated in ovarian most cancers.
Chosen serial evaluation of gene expression outcomes have been additional validated by immunohistochemical evaluation of ApoJ, claudin-3, claudin-4, and epithelial mobile adhesion molecule in archival materials. These experiments offered further proof of the relevance of our findings in vivo. The publicly out there expression information reported right here ought to stimulate and support additional analysis within the area of ovarian most cancers.

Deoxynivalenol: toxicology and potential results on people.

Deoxynivalenol (DON) is a mycotoxin that generally contaminates cereal-based meals worldwide. On the molecular degree, DON disrupts regular cell perform by inhibiting protein synthesis by way of binding to the ribosome and by activating essential mobile kinases concerned in sign transduction associated to proliferation, differentiation, and apoptosis.
Relative to toxicity, there are marked species variations, with the pig being most delicate to DON, adopted by rodent>> canine>> cat>> poultry>> ruminants. The physiologic parameter that’s most delicate to low-level DON publicity is the emetic response, with as little as 0.05 to 0.1 mg/kg physique weight (bw) inducing vomiting in swine and canines.
Chinese language epidemiological research recommend that DON might also produce emetic results in people. With respect to power results, development (anorexia and decreased dietary effectivity), immune perform, (enhancement and suppression), and replica (lowered litter measurement) are additionally adversely affected by DON in animals, whereas incidence of neoplasia will not be affected.
When hazard evaluations have been carried out utilizing present power toxicity information and customary security components employed for anthropogenic components/contaminants in meals, tolerable day by day intakes (TDIs) starting from 1 to five microg/kg bw have been generated.
On condition that essential information gaps nonetheless exist concerning the potential well being results of DON, further analysis is required to enhance capability for assessing hostile well being results of this mycotoxin.
Vital areas for future DON analysis embrace molecular mechanisms underlying toxicity, sensitivity of human cells/tissues relative to different species, emetic results in primates, epidemiological affiliation with gastroenteritis and power illness in people, and surveillance in cereal crops worldwide.

The sort VI secretion toolkit.

Bacterial secretion programs are macromolecular complexes that launch virulence components into the medium or translocate them into the goal host cell. These programs are widespread in micro organism permitting them to contaminate eukaryotic cells and survive or replicate inside them.
A brand new secretion system, the kind VI secretion system (T6SS), was lately described and characterised in a number of pathogens. Genomic information recommend that T6SS exist in most micro organism that come into shut contact with eukaryotic cells, together with plant and animal pathogens.

293AD Cell Line

AD-100 1 vial
EUR 365

293AAV Cell Line

AAV-100 1 vial
EUR 405

293LTV Cell Line

LTV-100 1 vial
EUR 405

293RTV Cell Line

RV-100 1 vial
EUR 405

StemTAG Stem Cell Colony Formation Assay (Cell Recovery Compatible)

CBA-325 96 assays
EUR 1027.2
Description: Our StemTAG 96-Well Stem Cell Colony Formation Assay provides a high-throughput method to quantify ES cells in just 7-10 days, and no manual cell counting is required. Once colonies are formed, they may be analyzed in three different ways: 1. Lyse cells, then quantify in a fluorescence plate reader using dye included in the kit; 2. Lyse cells, then quantify alkaline phosphatase activity using reagents provided; or 3. Recover colonies from matrix for further culture or analysis.

StemTAG Stem Cell Colony Formation Assay (Cell Recovery Compatible)

CBA-325-5 5 x 96 assays
EUR 4033.2
Description: Our StemTAG 96-Well Stem Cell Colony Formation Assay provides a high-throughput method to quantify ES cells in just 7-10 days, and no manual cell counting is required. Once colonies are formed, they may be analyzed in three different ways: 1. Lyse cells, then quantify in a fluorescence plate reader using dye included in the kit; 2. Lyse cells, then quantify alkaline phosphatase activity using reagents provided; or 3. Recover colonies from matrix for further culture or analysis.

CytoSelect™ Cell Transformation Assay (Cell Recovery Compatible), Colorimetric

CBA-135 96 assays
EUR 715

CytoSelect™ Cell Transformation Assay (Cell Recovery Compatible), Colorimetric

CBA-135-5 5 x 96 assays
EUR 3095

CytoSelect™ Cell Transformation Assay (Cell Recovery Compatible), Fluorometric

CBA-140 96 assays
EUR 750

CytoSelect™ Cell Transformation Assay (Cell Recovery Compatible), Fluorometric

CBA-140-5 5 x 96 assays
EUR 3215

293/GFP Cell Line

AKR-200 1 vial
EUR 460

T47D/GFP Cell Line

AKR-208 1 vial
EUR 686.4
Description: T47D/GFP Cell Line stably expresses GFP and otherwise exhibits the same characteristics of the parental cell line.

A549/GFP Cell Line

AKR-209 1 vial
EUR 460

HeLa/GFP Cell Line

AKR-213 1 vial
EUR 460

293/Cas9 Cell Line

AKR-5110 1 vial
EUR 460

HeLa/Cas9 Cell Line

AKR-5111 1 vial
EUR 460

NIH3T3/GFP Cell Line

AKR-214 1 vial
EUR 460

NIH3T3/Cas9 Cell Line

AKR-5104 1 vial
EUR 460

CytoSelect Cell Transformation Assay (Cell Recovery Compatible), Colorimetric, Trial Size

CBA-135-T 24 assays
EUR 518.4
Description: CytoSelect 96-Well Cell Transformation Assays (Cell Recovery Compatible) provide a robust system for detecting transformed cells, screening cell transformation inhibitors, and determining in vitro drug sensitivity. A proprietary modified soft agar matrix allows you to either quantify cells using the included fluorescent dye, or recover the cells for further analysis.

MCF-7/Luc Cell Line

AKR-234 1 vial
EUR 686.4
Description: MCF-7/Luc Cell Line stably expresses luciferase and otherwise exhibits the same characteristics of the parental cell line.

SKOV-3/Luc Cell Line

AKR-232 1 vial
EUR 686.4
Description: SKOV-3/Luc Cell Line stably expresses luciferase and otherwise exhibits the same characteristics of the parental cell line.

OVCAR-5/RFP Cell Line

AKR-254 1 vial
EUR 686.4
Description: OVCAR-5/RFP Cell Line stably expresses RFP and otherwise exhibits the same characteristics of the parental cell line.

CD14, CT (CD14, Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14, urinary form, Monocyte differentiation antigen CD14, membrane-bound form) (AP)

MBS6282773-02mL 0.2mL
EUR 980

CD14, CT (CD14, Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14, urinary form, Monocyte differentiation antigen CD14, membrane-bound form) (AP)

MBS6282773-5x02mL 5x0.2mL
EUR 4250

CD14, CT (CD14, Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14, urinary form, Monocyte differentiation antigen CD14, membrane-bound form) (APC)

MBS6282774-02mL 0.2mL
EUR 980

CD14, CT (CD14, Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14, urinary form, Monocyte differentiation antigen CD14, membrane-bound form) (APC)

MBS6282774-5x02mL 5x0.2mL
EUR 4250

CD14, CT (CD14, Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14, urinary form, Monocyte differentiation antigen CD14, membrane-bound form) (Biotin)

MBS6282775-02mL 0.2mL
EUR 980

CD14, CT (CD14, Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14, urinary form, Monocyte differentiation antigen CD14, membrane-bound form) (Biotin)

MBS6282775-5x02mL 5x0.2mL
EUR 4250

CD14, CT (CD14, Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14, urinary form, Monocyte differentiation antigen CD14, membrane-bound form) (FITC)

MBS6282776-02mL 0.2mL
EUR 980

CD14, CT (CD14, Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14, urinary form, Monocyte differentiation antigen CD14, membrane-bound form) (FITC)

MBS6282776-5x02mL 5x0.2mL
EUR 4250

CD14, CT (CD14, Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14, urinary form, Monocyte differentiation antigen CD14, membrane-bound form) (HRP)

MBS6282777-02mL 0.2mL
EUR 980

CD14, CT (CD14, Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14, urinary form, Monocyte differentiation antigen CD14, membrane-bound form) (HRP)

MBS6282777-5x02mL 5x0.2mL
EUR 4250

CD14, CT (CD14, Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14, urinary form, Monocyte differentiation antigen CD14, membrane-bound form) (PE)

MBS6282783-02mL 0.2mL
EUR 980

CD14, CT (CD14, Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14, urinary form, Monocyte differentiation antigen CD14, membrane-bound form) (PE)

MBS6282783-5x02mL 5x0.2mL
EUR 4250

CD14, NT (CD14, Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14, urinary form, Monocyte differentiation antigen CD14, membrane-bound form) (AP)

MBS6282784-02mL 0.2mL
EUR 980

CD14, NT (CD14, Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14, urinary form, Monocyte differentiation antigen CD14, membrane-bound form) (AP)

MBS6282784-5x02mL 5x0.2mL
EUR 4250

CD14, NT (CD14, Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14, urinary form, Monocyte differentiation antigen CD14, membrane-bound form) (APC)

MBS6282785-02mL 0.2mL
EUR 980

CD14, NT (CD14, Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14, urinary form, Monocyte differentiation antigen CD14, membrane-bound form) (APC)

MBS6282785-5x02mL 5x0.2mL
EUR 4250

CD14, NT (CD14, Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14, urinary form, Monocyte differentiation antigen CD14, membrane-bound form) (Biotin)

MBS6282786-02mL 0.2mL
EUR 980

CD14, NT (CD14, Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14, urinary form, Monocyte differentiation antigen CD14, membrane-bound form) (Biotin)

MBS6282786-5x02mL 5x0.2mL
EUR 4250

CD14, NT (CD14, Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14, urinary form, Monocyte differentiation antigen CD14, membrane-bound form) (FITC)

MBS6282787-02mL 0.2mL
EUR 980

CD14, NT (CD14, Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14, urinary form, Monocyte differentiation antigen CD14, membrane-bound form) (FITC)

MBS6282787-5x02mL 5x0.2mL
EUR 4250

CD14, NT (CD14, Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14, urinary form, Monocyte differentiation antigen CD14, membrane-bound form) (HRP)

MBS6282788-02mL 0.2mL
EUR 980

CD14, NT (CD14, Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14, urinary form, Monocyte differentiation antigen CD14, membrane-bound form) (HRP)

MBS6282788-5x02mL 5x0.2mL
EUR 4250

CD14, NT (CD14, Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14, urinary form, Monocyte differentiation antigen CD14, membrane-bound form) (PE)

MBS6282794-02mL 0.2mL
EUR 980

CD14, NT (CD14, Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14, urinary form, Monocyte differentiation antigen CD14, membrane-bound form) (PE)

MBS6282794-5x02mL 5x0.2mL
EUR 4250

Human Primary Monocyte-derived Dendritic Cells

T5403 5x10^5 cells / 1.0 ml
EUR 975

CytoSelect 96-Well Cell Transformation Assay (Cell Recovery Compatible, Fluorometric), Trial Size

CBA-140-T 24 assays
EUR 547.2
Description: CytoSelect 96-Well Cell Transformation Assays (Cell Recovery Compatible) provide a robust system for detecting transformed cells, screening cell transformation inhibitors, and determining in vitro drug sensitivity. A proprietary modified soft agar matrix allows you to either quantify cells using the included fluorescent dye, or recover the cells for further analysis.

Collagen-based Cell Contraction Assay

CBA-201 24 assays
EUR 420

CD14, CT (CD14, Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14, urinary form, Monocyte differentiation antigen CD14, membrane-bound form) (MaxLight 405)

MBS6282778-01mL 0.1mL
EUR 980

CD14, CT (CD14, Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14, urinary form, Monocyte differentiation antigen CD14, membrane-bound form) (MaxLight 405)

MBS6282778-5x01mL 5x0.1mL
EUR 4250

CD14, CT (CD14, Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14, urinary form, Monocyte differentiation antigen CD14, membrane-bound form) (MaxLight 490)

MBS6282779-01mL 0.1mL
EUR 980

CD14, CT (CD14, Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14, urinary form, Monocyte differentiation antigen CD14, membrane-bound form) (MaxLight 490)

MBS6282779-5x01mL 5x0.1mL
EUR 4250

CD14, CT (CD14, Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14, urinary form, Monocyte differentiation antigen CD14, membrane-bound form) (MaxLight 550)

MBS6282780-01mL 0.1mL
EUR 980

CD14, CT (CD14, Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14, urinary form, Monocyte differentiation antigen CD14, membrane-bound form) (MaxLight 550)

MBS6282780-5x01mL 5x0.1mL
EUR 4250

CD14, CT (CD14, Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14, urinary form, Monocyte differentiation antigen CD14, membrane-bound form) (MaxLight 650)

MBS6282781-01mL 0.1mL
EUR 980

CD14, CT (CD14, Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14, urinary form, Monocyte differentiation antigen CD14, membrane-bound form) (MaxLight 650)

MBS6282781-5x01mL 5x0.1mL
EUR 4250

CD14, CT (CD14, Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14, urinary form, Monocyte differentiation antigen CD14, membrane-bound form) (MaxLight 750)

MBS6282782-01mL 0.1mL
EUR 980

CD14, CT (CD14, Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14, urinary form, Monocyte differentiation antigen CD14, membrane-bound form) (MaxLight 750)

MBS6282782-5x01mL 5x0.1mL
EUR 4250

CD14, NT (CD14, Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14, urinary form, Monocyte differentiation antigen CD14, membrane-bound form) (MaxLight 405)

MBS6282789-01mL 0.1mL
EUR 980

CD14, NT (CD14, Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14, urinary form, Monocyte differentiation antigen CD14, membrane-bound form) (MaxLight 405)

MBS6282789-5x01mL 5x0.1mL
EUR 4250

CD14, NT (CD14, Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14, urinary form, Monocyte differentiation antigen CD14, membrane-bound form) (MaxLight 490)

MBS6282790-01mL 0.1mL
EUR 980

CD14, NT (CD14, Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14, urinary form, Monocyte differentiation antigen CD14, membrane-bound form) (MaxLight 490)

MBS6282790-5x01mL 5x0.1mL
EUR 4250

CD14, NT (CD14, Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14, urinary form, Monocyte differentiation antigen CD14, membrane-bound form) (MaxLight 550)

MBS6282791-01mL 0.1mL
EUR 980

CD14, NT (CD14, Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14, urinary form, Monocyte differentiation antigen CD14, membrane-bound form) (MaxLight 550)

MBS6282791-5x01mL 5x0.1mL
EUR 4250

CD14, NT (CD14, Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14, urinary form, Monocyte differentiation antigen CD14, membrane-bound form) (MaxLight 650)

MBS6282792-01mL 0.1mL
EUR 980

CD14, NT (CD14, Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14, urinary form, Monocyte differentiation antigen CD14, membrane-bound form) (MaxLight 650)

MBS6282792-5x01mL 5x0.1mL
EUR 4250

CD14, NT (CD14, Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14, urinary form, Monocyte differentiation antigen CD14, membrane-bound form) (MaxLight 750)

MBS6282793-01mL 0.1mL
EUR 980

CD14, NT (CD14, Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14, urinary form, Monocyte differentiation antigen CD14, membrane-bound form) (MaxLight 750)

MBS6282793-5x01mL 5x0.1mL
EUR 4250

Radius 384-Well Cell Migration Assay

CBA-127 384 assays
EUR 721.2
Description: The Radius Cell Migration Assay provides a unique alternative to conventional cell migration assays using the Boyden chamber. Unlike Boyden chamber assays which may only be analyzed at endpoint, the Radius assay uses a proprietary cell culture plate containing a carefully-defined biocompatible hydrogel (Radius gel) spot centralized at the bottom of each well. When cells are seeded in the well, they will attach everywhere except on the Radius gel, creating a cell-free zone. Following cell seeding the Radius gel is removed, allowing migratory cells to move across the area and close the gap.

Radius 384-Well Cell Migration Assay

CBA-127-5 5 x 384 wells
EUR 2802
Description: The Radius Cell Migration Assay provides a unique alternative to conventional cell migration assays using the Boyden chamber. Unlike Boyden chamber assays which may only be analyzed at endpoint, the Radius assay uses a proprietary cell culture plate containing a carefully-defined biocompatible hydrogel (Radius gel) spot centralized at the bottom of each well. When cells are seeded in the well, they will attach everywhere except on the Radius gel, creating a cell-free zone. Following cell seeding the Radius gel is removed, allowing migratory cells to move across the area and close the gap.

HIF-1 Alpha Cell Based ELISA Kit

CBA-281 96 assays
EUR 734.4
Description: Cell Biolabs? HIF-1 Cell Based ELISA Kit is an immunoassay developed for rapid detection of HIF-1 Alpha in fixed cells. Cells on a microplate are stimulated for HIF-1 Alpha stabilization, fixed, permeabilized, and then neutralized in the well. HIF-1 Alpha is then detected with an anti-HIF-1 alpha antibody followed by an HRP conjugated secondary antibody. Each kit provides sufficient reagents to perform up to a total of 96 assays and can detect HIF-1 Alpha from human, mouse, or rat.

CytoSelect™ MTT Cell Proliferation Assay

CBA-252 960 assays
EUR 320

Radius™ 24-Well Cell Migration Assay

CBA-125 24 assays
EUR 425

Radius™ 24-Well Cell Migration Assay

CBA-125-5 5 x 24 assays
EUR 1820

Radius™ 96-Well Cell Migration Assay

CBA-126 96 assays
EUR 495

Radius™ 96-Well Cell Migration Assay

CBA-126-5 5 x 96 assays
EUR 2095

Radius™ 48-Well Cell Migration Assay

CBA-5037 48 assays
EUR 445

Radius™ 48-Well Cell Migration Assay

CBA-5037-5 5 x 48 assays
EUR 1895

CytoSelect Cell Proliferation Assay Reagent (Fluorometric)

CBA-250 10 mL
EUR 490.8
Description: Cell Biolabs? CytoSelect Cell Proliferation Assay Reagent (Fluorometric) provides a fluorometric format for measuring and monitoring cell proliferation. Cells can be plated and then treated with compounds or agents that affect proliferation.  Cells are then incubated with the proliferation reagent.  Upon entering metabolically active live cells, the non-fluorescent proliferation reagent is converted into a bright red fluorescent form. An increase in cell proliferation is accompanied by increased fluorescent signal, while a decrease in cell proliferation (and signal) can indicate the toxic effects of compounds or suboptimal culture conditions.  The assay principles are basic and can be applied to most eukaryotic cell lines, including adherent and non-adherent cells and certain tissues.  This cell proliferation reagent can be used to detect proliferation in bacteria, yeast, fungi, protozoa as well as cultured mammalian and piscine cells. The kit contains sufficient reagents for the evaluation of 960 assays in ten 96-well plates or 192 assays in eight 24-well plates.

CytoSelect™ BrdU Cell Proliferation ELISA Kit

CBA-251 96 assays
EUR 455

CytoSelect™ 96-well Cell Transformation Assay

CBA-130 96 assays
EUR 640

CytoSelect™ 96-well Cell Transformation Assay

CBA-130-5 5 x 96 assays
EUR 2695

CytoSelect™ Cell Viability and Cytotoxicity Assay

CBA-240 96 assays
EUR 305

Platinum-E Retroviral Packaging Cell Line, Ecotropic

RV-101 1 vial
EUR 770

Platinum-GP Retroviral Packaging Cell Line, Pantropic

RV-103 1 vial
EUR 770

CytoSelect 24-well Laminin Cell Invasion, Colorimetric

CBA-110-LN 12 assays
EUR 714
Description: The ability of malignant tumor cells to invade normal surrounding tissue contributes in large part to the morbidity and mortality of cancers. Cell invasion requires several distinct cellular functions including adhesion, motility, detachment, and extracellular matrix proteolysis. Our CytoSelect Cell Invasion Assays utilize precoated inserts to assay the invasive properties of tumor cells. Invasive cells can be quantified in 24-well plates on either a standard microplate reader or a fluorescence plate reader. Inserts are precoated on the top of the membrane with Laminin.

Platinum-A Retroviral Packaging Cell Line, Amphotropic

RV-102 1 vial
EUR 770

CytoSelect™ 24-Well Cell Co-Culture System

CBA-160 24 assays
EUR 365

CytoSelect™ 24-Well Cell Co-Culture System

CBA-160-5 5 x 24 assays
EUR 1585

Total Protein - Murine Embryonic Stem Cell Line D3

CBA-305 500 ?g
EUR 414
Description:
  • Isolated from mouse ES-D3 cell line
  • Presented as 500 µg at 1 mg/mL in NP-40 Solubilization Buffer

CD14 (Monocyte Differentiation Antigen CD14, Myeloid Cell-specific Leucine-rich Glycoprotein)

MBS6507133-01mg 0.1mg
EUR 800

CD14 (Monocyte Differentiation Antigen CD14, Myeloid Cell-specific Leucine-rich Glycoprotein)

MBS6507133-5x01mg 5x0.1mg
EUR 3445

CytoSelect™ 48-Well Cell Contraction Assay Kit

CBA-5021 48 assays
EUR 575

CytoSelect 384-well Cell Transformation Assay, Fluorometric

CBA-145 384 assays
EUR 1208.4
Description: Our CytoSelect 384-Well Cell Transformation Assay uses a modified soft agar 3D matrix to support the formation of colonies by neoplastic cells. Quantitation of cell transformation is performed on a fluorescence plate reader.

CytoSelect 384-well Cell Transformation Assay, Fluorometric

CBA-145-5 5 x 384 assays
EUR 4681.2
Description: Our CytoSelect 384-Well Cell Transformation Assay uses a modified soft agar 3D matrix to support the formation of colonies by neoplastic cells. Quantitation of cell transformation is performed on a fluorescence plate reader.

CytoSelect™ Cell Proliferation Assay Reagent (Colorimetric)

CBA-253 10 mL
EUR 320

Radius 24-Well Cell Migration Assay, (Laminin Coated)

CBA-125-LN 24 assays
EUR 714
Description: The Radius Cell Migration Assay provides a unique alternative to conventional cell migration assays using the Boyden chamber. Unlike Boyden chamber assays which may only be analyzed at endpoint, the Radius assay uses a proprietary cell culture plate containing a carefully-defined biocompatible hydrogel (Radius gel) spot centralized at the bottom of each well. When cells are seeded in the well, they will attach everywhere except on the Radius gel, creating a cell-free zone. Following cell seeding the Radius gel is removed, allowing migratory cells to move across the area and close the gap.

StemTAG PCR Primer Set for Stem Cell Characterization

CBA-303 1 kit
EUR 470.4
Description: StemTAG PCR Primer Set for Stem Cell Characterization includes 7 primer pairs: Oct-4, NANOG, AFP, Flk-1, and NCAM, plus GAPDH and beta-actin as controls.

CytoSelect Clonogenic Tumor Cell Isolation Kit (5 preps)

CBA-155 5 preps
EUR 957.6
Description: Many solid tumors contain heterogeneous populations of normal and cancerous cells. Separation of these cell populations is key to an accurate assessment of the true genotypic and phenotypic differences between normal and tumor cells. Our CytoSelect Clonogenic Tumor Cell Isolation Kit uses a proprietary semisolid agar medium to facilitate formation of colonies by cells from solid tumors. Colonies are grown in either a 6-well plate or a 35mm culture dish. These colonies are isolated away from single (i.e. normal) cells by size filtration. The viable cells from these colonies can be easily recovered for further analysis.

Radius 24-Well Cell Migration Assay, (Fibronectin Coated)

CBA-125-FN 24 assays
EUR 714
Description: The Radius Cell Migration Assay provides a unique alternative to conventional cell migration assays using the Boyden chamber. Unlike Boyden chamber assays which may only be analyzed at endpoint, the Radius assay uses a proprietary cell culture plate containing a carefully-defined biocompatible hydrogel (Radius gel) spot centralized at the bottom of each well. When cells are seeded in the well, they will attach everywhere except on the Radius gel, creating a cell-free zone. Following cell seeding the Radius gel is removed, allowing migratory cells to move across the area and close the gap.

THP-1 Cell Slide (Human (1 yr infant, Male) peripheral blood monocyte, acute monocytic leukemia) (5 slides/pk)

HCLS-17008 1 pk
EUR 300

CytoSelect™ 24-well Collagen Cell Invasion, Colorimetric

CBA-110-COL 12 assays
EUR 535

Macrophage/Monocyte Antibody

abx415014-025mg 0.25 mg
EUR 777.6

Macrophage/Monocyte Antibody

abx415015-25ug 25 ug
EUR 360

Monocyte/Macrophage Antibody

abx415176-025mg 0.25 mg
EUR 710.4

Macrophage/Monocyte Antibody

abx415014-200l 200 µl
EUR 550

Macrophage/Monocyte Antibody

abx415015-200l 200 µl
EUR 200

Monocyte/Macrophage Antibody

abx415176-200l 200 µl
EUR 512.5

Monocyte Pervanadate Control

MBS474439-01mL 0.1mL
EUR 200

Monocyte Pervanadate Control

MBS474439-5x01mL 5x0.1mL
EUR 740

Monocyte + Pervanadate Treated

MBS474440-01mL 0.1mL
EUR 200

Monocyte + Pervanadate Treated

MBS474440-5x01mL 5x0.1mL
EUR 740

CytoSelect Proliferating Cell Nuclear Antigen (PCNA) ELISA Kit

CBA-254 96 assays
EUR 672
Description: Cell Biolabs? CytoSelect Proliferating Cell Nuclear Antigen (PCNA) ELISA Kit is an enzyme immunoassay developed for the detection and quantitation of PCNA from nuclear and whole cell extracts.  The kit detects PCNA from mouse, rat and human, and has a detection sensitivity limit of 12.5 ng/mLPCNA.  Each kit provides sufficient reagents to perform up to 96 assays including standard curve and unknown samples. 

Radius 24-Well Cell Migration Assay, (ECM Array Coated)

CBA-125-ECM 24 wells
EUR 838.8
Description: The Radius Cell Migration Assay provides a unique alternative to conventional cell migration assays using the Boyden chamber. Unlike Boyden chamber assays which may only be analyzed at endpoint, the Radius assay uses a proprietary cell culture plate containing a carefully-defined biocompatible hydrogel (Radius gel) spot centralized at the bottom of each well. When cells are seeded in the well, they will attach everywhere except on the Radius gel, creating a cell-free zone. Following cell seeding the Radius gel is removed, allowing migratory cells to move across the area and close the gap.

CytoSelect 48-well Cell Adhesion Assay (Laminin, Colorimetric)

CBA-056 48 assays
EUR 512.4
Description: Cell adhesion is a complex process involved in migration/invasion, embryogenesis, wound healing and tissue remodeling. Cells adhere to the extracellular matrix, forming complexes with cytoskeleton components that can affect cell motility, differentiation, proliferation, and survival. Our CytoSelect 48-Well Cell Adhesion Assays provide a fully quantitative method for the evaluation of cell adhesion. The 48-well plate is precoated with Laminin.

CytoSelect 48-well Cell Adhesion Assay (Laminin, Fluorometric)

CBA-057 48 assays
EUR 553.2
Description: Cell adhesion is a complex process involved in migration/invasion, embryogenesis, wound healing and tissue remodeling. Cells adhere to the extracellular matrix, forming complexes with cytoskeleton components that can affect cell motility, differentiation, proliferation, and survival. Our CytoSelect 48-Well Cell Adhesion Assays provide a fully quantitative method for the evaluation of cell adhesion. The 48-well plate is precoated with Laminin.

CytoSelect 24-well Laminin Cell Invasion Assay, Fluorometric

CBA-111-LN 12 assays
EUR 714
Description: The ability of malignant tumor cells to invade normal surrounding tissue contributes in large part to the morbidity and mortality of cancers. Cell invasion requires several distinct cellular functions including adhesion, motility, detachment, and extracellular matrix proteolysis. Our CytoSelect Cell Invasion Assays utilize precoated inserts to assay the invasive properties of tumor cells. Invasive cells can be quantified in 24-well plates on either a standard microplate reader or a fluorescence plate reader. Inserts are precoated on the top of the membrane with Laminin.

CytoSelect 96-well Laminin Cell Invasion Assay, Fluorometric

CBA-112-LN 96 assays
EUR 908.4
Description: The ability of malignant tumor cells to invade normal surrounding tissue contributes in large part to the morbidity and mortality of cancers. Cell invasion requires several distinct cellular functions including adhesion, motility, detachment, and extracellular matrix proteolysis. Our CytoSelect 96-Well Cell Invasion Assays utilize precoated inserts to assay the invasive properties of tumor cells. Invasive cells can be quantified in 96-well plates on a fluorescence plate reader. Inserts are precoated on the top of the membrane with Laminin.

CytoSelect 48-well Cell Adhesion Assay (Fibrinogen, Colorimetric)

CBA-058 48 assays
EUR 512.4
Description: Cell adhesion is a complex process involved in migration/invasion, embryogenesis, wound healing and tissue remodeling. Cells adhere to the extracellular matrix, forming complexes with cytoskeleton components that can affect cell motility, differentiation, proliferation, and survival. Our CytoSelect 48-Well Cell Adhesion Assays provide a fully quantitative method for the evaluation of cell adhesion. The 48-well plate is precoated with Fibrinogen.

CytoSelect 48-well Cell Adhesion Assay (Fibrinogen, Fluorometric)

CBA-059 48 assays
EUR 553.2
Description: Cell adhesion is a complex process involved in migration/invasion, embryogenesis, wound healing and tissue remodeling. Cells adhere to the extracellular matrix, forming complexes with cytoskeleton components that can affect cell motility, differentiation, proliferation, and survival. Our CytoSelect 48-Well Cell Adhesion Assays provide a fully quantitative method for the evaluation of cell adhesion. The 48-well plate is precoated with Fibrinogen.

Monocyte/Granulocyte Antibody

abx415381-01mg 0.1 mg
EUR 543.6

Monocyte/Granulocyte Antibody

abx415381-200l 200 µl
EUR 362.5

Monocyte (PMA-differentiated)

MBS474438-01mL 0.1mL
EUR 200

Monocyte (PMA-differentiated)

MBS474438-5x01mL 5x0.1mL
EUR 740
Many analysis teams at the moment are investigating the underlying mechanisms and the way in which through which the effector proteins translocated by this machine subvert host defences. This overview supplies an outline of our present information about sort VI secretion, specializing in gene regulation, parts of the secretion machine, substrate secretion and the mobile penalties for the host cell.

Leave a Comment