The immunology informationbase and evaluation portal (ImmPort) system is the archival repository and dissemination car for scientific and molecular informationunits created by analysis consortia funded by the Nationwide Institute of Allergy and Infectious Illnesses Division of Allergy, Immunology, and Transplantation.
With almost 100 informationunits now publicly out there and lots of of downloads per thirty days, ImmPort is a vital supply for uncooked information and protocols from scientific trials, mechanistic research, and novel strategies for mobile and molecular measurements.
To facilitate information switch, templates for information illustration and customary working procedures have additionally been created and are additionally publicly out there. ImmPort facilitates transparency and reproducibility in immunology analysis, serves as an vital useful resource for training, and allows newly generated hypotheses and information-driven science.
Cognitive management deficits in schizophrenia: mechanisms and that means.
Though schizophrenia is an sickness that has been traditionally characterised by the presence of optimistic symptomatology, a long time of analysis spotlight the significance of cognitive deficits on this dysfunction. This overview proposes that the theoretical mannequin of cognitive management, which is predicated on up to date cognitive neuroscience, supplies a unifying principle for the cognitive and neural abnormalities underlying larger cognitive dysfunction in schizophrenia.
To help this mannequin, we define converging proof from a number of modalities (eg, structural and purposeful neuroimaging, pharmacological information, and animal fashions) and samples (eg, scientific excessive danger, genetic excessive danger, first episode, and power topics) to emphasise how dysfunction in cognitive management mechanisms supported by the prefrontal cortex contribute to the pathophysiology of upper cognitive deficits in schizophrenia.
Our mannequin supplies a theoretical hyperlink between mobile abnormalities (eg, reductions in dentritic spines, interneuronal dysfunction), purposeful disturbances in native circuit perform (eg, gamma abnormalities), altered inter-regional cortical connectivity, a variety of upper cognitive deficits, and symptom presentation (eg, disorganization) within the dysfunction.
Lastly, we talk about current advances within the neuropharmacology of cognition and the way they will inform a focused method to the event of efficient therapies for this disabling side of schizophrenia.
Giant-scale serial evaluation of gene expression reveals genes differentially expressed in ovarian most cancers.
Difficulties within the detection, prognosis, and remedy of ovarian most cancers lead to an general low survival price of girls with this illness. A greater understanding of the pathways concerned in ovarian tumorigenesis will doubtless present new targets for early and efficient intervention.
Right here, now we have used serial evaluation of gene expression (SAGE) to generate world gene expression profiles from numerous ovarian cell traces and tissues, together with major cancers, ovarian floor epithelia cells, and cystadenoma cells. The profiles have been used to check general patterns of gene expression and to establish differentially expressed genes.
We’ve got sequenced a complete of 385,000 tags, yielding >56,000 genes expressed in 10 totally different libraries derived from ovarian tissues. On the whole, ovarian most cancers cell traces confirmed comparatively excessive ranges of similarity to libraries from different most cancers cell traces, whatever the tissue of origin (ovarian or colon), indicating that these traces had misplaced lots of their tissue-specific expression patterns.
In distinction, immortalized ovarian floor epithelia and ovarian cystadenoma cells confirmed a lot larger similarity to major ovarian carcinomas than to major colon carcinomas. Major tissue specimens subsequently seemed to be a greater mannequin for gene expression analyses.
Utilizing the expression profiles described above and stringent choice standards, now we have recognized a lot of genes extremely differentially expressed between nontransformed ovarian epithelia and ovarian carcinomas. A number of the genes recognized are already identified to be overexpressed in ovarian most cancers, however a number of signify novel candidates.
Lots of the genes up-regulated in ovarian most cancers signify floor or secreted proteins comparable to claudin-Three and -4, HE4, mucin-1, epithelial mobile adhesion molecule, and mesothelin. Curiously, each apolipoprotein E (ApoE) and ApoJ, two proteins concerned in lipid homeostasis, are among the many genes extremely up-regulated in ovarian most cancers.
Chosen serial evaluation of gene expression outcomes have been additional validated by immunohistochemical evaluation of ApoJ, claudin-3, claudin-4, and epithelial mobile adhesion molecule in archival materials. These experiments offered further proof of the relevance of our findings in vivo. The publicly out there expression information reported right here ought to stimulate and support additional analysis within the area of ovarian most cancers.
Deoxynivalenol: toxicology and potential results on people.
Deoxynivalenol (DON) is a mycotoxin that generally contaminates cereal-based meals worldwide. On the molecular degree, DON disrupts regular cell perform by inhibiting protein synthesis by way of binding to the ribosome and by activating essential mobile kinases concerned in sign transduction associated to proliferation, differentiation, and apoptosis.
Relative to toxicity, there are marked species variations, with the pig being most delicate to DON, adopted by rodent>> canine>> cat>> poultry>> ruminants. The physiologic parameter that’s most delicate to low-level DON publicity is the emetic response, with as little as 0.05 to 0.1 mg/kg physique weight (bw) inducing vomiting in swine and canines.
Chinese language epidemiological research recommend that DON might also produce emetic results in people. With respect to power results, development (anorexia and decreased dietary effectivity), immune perform, (enhancement and suppression), and replica (lowered litter measurement) are additionally adversely affected by DON in animals, whereas incidence of neoplasia will not be affected.
When hazard evaluations have been carried out utilizing present power toxicity information and customary security components employed for anthropogenic components/contaminants in meals, tolerable day by day intakes (TDIs) starting from 1 to five microg/kg bw have been generated.
On condition that essential information gaps nonetheless exist concerning the potential well being results of DON, further analysis is required to enhance capability for assessing hostile well being results of this mycotoxin.
Vital areas for future DON analysis embrace molecular mechanisms underlying toxicity, sensitivity of human cells/tissues relative to different species, emetic results in primates, epidemiological affiliation with gastroenteritis and power illness in people, and surveillance in cereal crops worldwide.
The sort VI secretion toolkit.
Bacterial secretion programs are macromolecular complexes that launch virulence components into the medium or translocate them into the goal host cell. These programs are widespread in micro organism permitting them to contaminate eukaryotic cells and survive or replicate inside them.
A brand new secretion system, the kind VI secretion system (T6SS), was lately described and characterised in a number of pathogens. Genomic information recommend that T6SS exist in most micro organism that come into shut contact with eukaryotic cells, together with plant and animal pathogens.
 Fmoc-b-Ala-OH |
|||
| B-1025.0025 | Bachem | 25.0g | EUR 236 |
|
Description: Sum Formula: C18H17NO4; CAS# [35737-10-1] |
|||
Fmoc-b-Ala-OH |
|||
| B-1025.0100 | Bachem | 100.0g | EUR 635 |
|
Description: Sum Formula: C18H17NO4; CAS# [35737-10-1] |
|||
 Fmoc-b-Ala-OPfp |
|||
| B-1765.0005 | Bachem | 5.0g | EUR 236 |
|
Description: Sum Formula: C24H16F5NO4; CAS# [149303-38-8] |
|||
Fmoc-b-Ala-OPfp |
|||
| B-1765.0025 | Bachem | 25.0g | EUR 841 |
|
Description: Sum Formula: C24H16F5NO4; CAS# [149303-38-8] |
|||
 Modified Human Apolipoprotein B-100) Malondialdehyde (MDA) Modified Human Apolipoprotein B-100 |
|||
| STA-211 | Cell Biolabs | 100 µg | EUR 624 |
|
Description:
|
|||
 QuickTiter Hepatitis B "e" Antigen (HBeAg) ELISA Kit |
|||
| VPK-5003 | Cell Biolabs | 96 assays | EUR 914 |
|
Description: The QuickTiter Hepatitis B "e" Antigen ELISA Kit measures HBeAg with sensitivity as low as 150 pg/mL. Reagents are sufficient for 96 wells including standards and unknown samples. |
|||
QuickTiter Hepatitis B "e" Antigen (HBeAg) ELISA Kit |
|||
| VPK-5003-5 | Cell Biolabs | 5 x 96 assays | EUR 3756 |
|
Description: The QuickTiter Hepatitis B "e" Antigen ELISA Kit measures HBeAg with sensitivity as low as 150 pg/mL. Reagents are sufficient for 5x96 wells including standards and unknown samples. |
|||
 ELISA Kit) QuickTiter Hepatitis B Surface Antigen (HBsAg) ELISA Kit |
|||
| VPK-5004 | Cell Biolabs | 96 assays | EUR 914 |
|
Description: The QuickTiter Hepatitis B Surface Antigen ELISA Kit measures HBsAg with sensitivity as low as 1 ng/mL. Reagents are sufficient for 96 wells including standards and unknown samples. |
|||
QuickTiter Hepatitis B Surface Antigen (HBsAg) ELISA Kit |
|||
| VPK-5004-5 | Cell Biolabs | 5 x 96 assays | EUR 3756 |
|
Description: The QuickTiter Hepatitis B Surface Antigen ELISA Kit measures HBsAg with sensitivity as low as 1 ng/mL. Reagents are sufficient for 5x96 wells including standards and unknown samples. |
|||
 Fmoc-b-cyclohexyl-Ala-OH |
|||
| B-1975.0001 | Bachem | 1.0g | EUR 126 |
|
Description: Sum Formula: C24H27NO4; CAS# [135673-97-1] |
|||
Fmoc-b-cyclohexyl-Ala-OH |
|||
| B-1975.0005 | Bachem | 5.0g | EUR 418 |
|
Description: Sum Formula: C24H27NO4; CAS# [135673-97-1] |
|||
Fmoc-b-cyclohexyl-Ala-OH |
|||
| B-1975.0025 | Bachem | 25.0g | EUR 1192 |
|
Description: Sum Formula: C24H27NO4; CAS# [135673-97-1] |
|||
 Fmoc-b-cyclopropyl-Ala-OH |
|||
| B-2905.0001 | Bachem | 1.0g | EUR 345 |
|
Description: Sum Formula: C21H21NO4; CAS# [214750-76-2] |
|||
Fmoc-b-cyclopropyl-Ala-OH |
|||
| B-2905.0005 | Bachem | 5.0g | EUR 1301 |
|
Description: Sum Formula: C21H21NO4; CAS# [214750-76-2] |
|||
 ELISA Kit) Bovine Monocyte Chemotactic Protein 2 (MCP2) ELISA Kit |
|||
| RDR-MCP2-b-48Tests | Reddot Biotech | 48 Tests | EUR 580 |
Bovine Monocyte Chemotactic Protein 2 (MCP2) ELISA Kit |
|||
| RDR-MCP2-b-96Tests | Reddot Biotech | 96 Tests | EUR 807 |
Bovine Monocyte Chemotactic Protein 2 (MCP2) ELISA Kit |
|||
| RD-MCP2-b-48Tests | Reddot Biotech | 48 Tests | EUR 555 |
Bovine Monocyte Chemotactic Protein 2 (MCP2) ELISA Kit |
|||
| RD-MCP2-b-96Tests | Reddot Biotech | 96 Tests | EUR 771 |
Bovine Monocyte Chemotactic Protein 2 (MCP2) ELISA Kit |
|||
| DLR-MCP2-b-48T | DL Develop | 48T | EUR 547 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Bovine Monocyte Chemotactic Protein 2 (MCP2) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
|||
Bovine Monocyte Chemotactic Protein 2 (MCP2) ELISA Kit |
|||
| DLR-MCP2-b-96T | DL Develop | 96T | EUR 715 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Bovine Monocyte Chemotactic Protein 2 (MCP2) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
|||
 Goat Anti-Human Apolipoprotein B-100/48 Polyclonal Antibody |
|||
| STA-134 | Cell Biolabs | 100 µg | EUR 496 |
|
Description: Goat Anti-Human Apolipoprotein B-100/48 Polyclonal Antibody is Affinity purified and suitable for Western blot or ELISA. 100 µg. |
|||
 ELISA Kit) Scavenger Receptor Class B Member 1 (SRB1) ELISA Kit |
|||
| STA-630 | Cell Biolabs | 96 assays | EUR 618 |
|
Description: Scavenger Receptor Class B Member 1 (SRB1 or SCARB1) is a transmembrane protein that plays a critical role in the reverse cholesterol transport pathway where cholesterol is cleared from macrophages and peripheral tissues and transported to the liver. This ELISA kit provides a convenient format for the quantitation of SRB1 in human and rodent samples. |
|||
, Colorimetric) CytoSelect Cell Transformation Assay (Cell Recovery Compatible), Colorimetric |
|||
| CBA-135 | Cell Biolabs | 96 assays | EUR 821 |
|
Description: CytoSelect 96-Well Cell Transformation Assays (Cell Recovery Compatible) provide a robust system for detecting transformed cells, screening cell transformation inhibitors, and determining in vitro drug sensitivity. A proprietary modified soft agar matrix allows you to either quantify cells using the included fluorescent dye, or recover the cells for further analysis. |
|||
CytoSelect Cell Transformation Assay (Cell Recovery Compatible), Colorimetric |
|||
| CBA-135-5 | Cell Biolabs | 5 x 96 assays | EUR 3356 |
|
Description: CytoSelect 96-Well Cell Transformation Assays (Cell Recovery Compatible) provide a robust system for detecting transformed cells, screening cell transformation inhibitors, and determining in vitro drug sensitivity. A proprietary modified soft agar matrix allows you to either quantify cells using the included fluorescent dye, or recover the cells for further analysis. |
|||
, Fluorometric) CytoSelect Cell Transformation Assay (Cell Recovery Compatible), Fluorometric |
|||
| CBA-140 | Cell Biolabs | 96 assays | EUR 856 |
|
Description: CytoSelect 96-Well Cell Transformation Assays (Cell Recovery Compatible) provide a robust system for detecting transformed cells, screening cell transformation inhibitors, and determining in vitro drug sensitivity. A proprietary modified soft agar matrix allows you to either quantify cells using the included fluorescent dye, or recover the cells for further analysis. |
|||
CytoSelect Cell Transformation Assay (Cell Recovery Compatible), Fluorometric |
|||
| CBA-140-5 | Cell Biolabs | 5 x 96 assays | EUR 3483 |
|
Description: CytoSelect 96-Well Cell Transformation Assays (Cell Recovery Compatible) provide a robust system for detecting transformed cells, screening cell transformation inhibitors, and determining in vitro drug sensitivity. A proprietary modified soft agar matrix allows you to either quantify cells using the included fluorescent dye, or recover the cells for further analysis. |
|||
 RhoB Activation Assay Kit, Trial Size |
|||
| STA-403-B-T | Cell Biolabs | 5 assays | EUR 403 |
|
Description: Our Rho Activation Assays use visible agarose beads to selectively precipitate the active form of RhoA, RhoB or RhoC. The precipitated small GTPase is then detected by Western blot using a RhoA-, RhoB- or RhoC-specific antibody included in the kit. |
|||
 293LTV Cell Line |
|||
| LTV-100 | Cell Biolabs | 1 vial | EUR 508 |
|
Description: The 293LTV Cell Line is derived from the parental 293 cells but selected for attributes that increase lentiviral production, including fimrer attachment and larger surface area. |
|||
 293AD Cell Line |
|||
| AD-100 | Cell Biolabs | 1 vial | EUR 461 |
|
Description: The 293AD Cell Line is derived from the parental 293 cells but selected for attributes that increase adenovirus production, including firmer attachment and larger surface area. |
|||
 293AAV Cell Line |
|||
| AAV-100 | Cell Biolabs | 1 vial | EUR 508 |
|
Description: The 293AAV Cell Line is derived from the parental 293 cells but selected for attributes that increase AAV production, including firmer attachment and larger surface area. |
|||
 293RTV Cell Line |
|||
| RV-100 | Cell Biolabs | 1 vial | EUR 508 |
|
Description: The 293RTV Cell Line is derived from the parental 293 cells but selected for attributes that increase retroviral production, including fimrer attachment and larger surface area. |
|||
 ELISA Kit) Bovine B-Cell Leukemia/Lymphoma 2 (Bcl2) ELISA Kit |
|||
| DLR-Bcl2-b-48T | DL Develop | 48T | EUR 493 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Bovine B-Cell Leukemia/Lymphoma 2 (Bcl2) in samples from serum, plasma, tissue homogenates or other biological fluids. |
|||
Bovine B-Cell Leukemia/Lymphoma 2 (Bcl2) ELISA Kit |
|||
| DLR-Bcl2-b-96T | DL Develop | 96T | EUR 641 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Bovine B-Cell Leukemia/Lymphoma 2 (Bcl2) in samples from serum, plasma, tissue homogenates or other biological fluids. |
|||
Bovine B-Cell Leukemia/Lymphoma 2 (Bcl2) ELISA Kit |
|||
| RD-Bcl2-b-48Tests | Reddot Biotech | 48 Tests | EUR 494 |
Bovine B-Cell Leukemia/Lymphoma 2 (Bcl2) ELISA Kit |
|||
| RD-Bcl2-b-96Tests | Reddot Biotech | 96 Tests | EUR 684 |
Bovine B-Cell Leukemia/Lymphoma 2 (Bcl2) ELISA Kit |
|||
| RDR-Bcl2-b-48Tests | Reddot Biotech | 48 Tests | EUR 516 |
Bovine B-Cell Leukemia/Lymphoma 2 (Bcl2) ELISA Kit |
|||
| RDR-Bcl2-b-96Tests | Reddot Biotech | 96 Tests | EUR 716 |
-Ala-OH) Fmoc-b-(2-thienyl)-Ala-OH |
|||
| B-1665.0001 | Bachem | 1.0g | EUR 284 |
|
Description: Sum Formula: C22H19NO4S; CAS# [130309-35-2] |
|||
Fmoc-b-(2-thienyl)-Ala-OH |
|||
| B-1665.0005 | Bachem | 5.0g | EUR 1046 |
|
Description: Sum Formula: C22H19NO4S; CAS# [130309-35-2] |
|||
-Ala-OH) Fmoc-b-(3-pyridyl)-Ala-OH |
|||
| B-2005.0001 | Bachem | 1.0g | EUR 393 |
|
Description: Sum Formula: C23H20N2O4; CAS# [175453-07-3] |
|||
Fmoc-b-(3-pyridyl)-Ala-OH |
|||
| B-2005.0005 | Bachem | 5.0g | EUR 1482 |
|
Description: Sum Formula: C23H20N2O4; CAS# [175453-07-3] |
|||
 Fmoc-b-cyclohexyl-D-Ala-OH |
|||
| B-2345.0001 | Bachem | 1.0g | EUR 151 |
|
Description: Sum Formula: C24H27NO4; CAS# [144701-25-7] |
|||
Fmoc-b-cyclohexyl-D-Ala-OH |
|||
| B-2345.0005 | Bachem | 5.0g | EUR 515 |
|
Description: Sum Formula: C24H27NO4; CAS# [144701-25-7] |
|||
Fmoc-b-cyclohexyl-D-Ala-OH |
|||
| B-2345.0025 | Bachem | 25.0g | EUR 1965 |
|
Description: Sum Formula: C24H27NO4; CAS# [144701-25-7] |
|||
-Ala-OH) Fmoc-b-(3-benzothienyl)-Ala-OH |
|||
| B-2830.0001 | Bachem | 1.0g | EUR 212 |
|
Description: Sum Formula: C26H21NO4S; CAS# [177966-60-8] |
|||
Fmoc-b-(3-benzothienyl)-Ala-OH |
|||
| B-2830.0005 | Bachem | 5.0g | EUR 756 |
|
Description: Sum Formula: C26H21NO4S; CAS# [177966-60-8] |
|||
 Fmoc-b-cyclopropyl-D-Ala-OH |
|||
| B-2915.0001 | Bachem | 1.0g | EUR 587 |
|
Description: Sum Formula: C21H21NO4; CAS# [170642-29-2] |
|||
Fmoc-b-cyclopropyl-D-Ala-OH |
|||
| B-2915.0005 | Bachem | 5.0g | EUR 2255 |
|
Description: Sum Formula: C21H21NO4; CAS# [170642-29-2] |
|||
-Ala-OH) Fmoc-b-(2-quinolyl)-Ala-OH |
|||
| B-3165.0250 | Bachem | 250.0mg | EUR 381 |
|
Description: Sum Formula: C27H22N2O4; CAS# [214852-56-9] |
|||
Fmoc-b-(2-quinolyl)-Ala-OH |
|||
| B-3165.1000 | Bachem | 1.0g | EUR 1070 |
|
Description: Sum Formula: C27H22N2O4; CAS# [214852-56-9] |
|||
 Fmoc-b-azido-Aib-OH · BHA |
|||
| B-4530.0001 | Bachem | 1.0g | EUR 705 |
|
Description: Sum Formula: C19H18N4O4·C13H13N; CAS# [1926163-90-7] net |
|||
) StemTAG Stem Cell Colony Formation Assay (Cell Recovery Compatible) |
|||
| CBA-325 | Cell Biolabs | 96 assays | EUR 856 |
|
Description: Our StemTAG 96-Well Stem Cell Colony Formation Assay provides a high-throughput method to quantify ES cells in just 7-10 days, and no manual cell counting is required. Once colonies are formed, they may be analyzed in three different ways: 1. Lyse cells, then quantify in a fluorescence plate reader using dye included in the kit; 2. Lyse cells, then quantify alkaline phosphatase activity using reagents provided; or 3. Recover colonies from matrix for further culture or analysis. |
|||
StemTAG Stem Cell Colony Formation Assay (Cell Recovery Compatible) |
|||
| CBA-325-5 | Cell Biolabs | 5 x 96 assays | EUR 3361 |
|
Description: Our StemTAG 96-Well Stem Cell Colony Formation Assay provides a high-throughput method to quantify ES cells in just 7-10 days, and no manual cell counting is required. Once colonies are formed, they may be analyzed in three different ways: 1. Lyse cells, then quantify in a fluorescence plate reader using dye included in the kit; 2. Lyse cells, then quantify alkaline phosphatase activity using reagents provided; or 3. Recover colonies from matrix for further culture or analysis. |
|||
, Colorimetric, Trial Size) CytoSelect Cell Transformation Assay (Cell Recovery Compatible), Colorimetric, Trial Size |
|||
| CBA-135-T | Cell Biolabs | 24 assays | EUR 432 |
|
Description: CytoSelect 96-Well Cell Transformation Assays (Cell Recovery Compatible) provide a robust system for detecting transformed cells, screening cell transformation inhibitors, and determining in vitro drug sensitivity. A proprietary modified soft agar matrix allows you to either quantify cells using the included fluorescent dye, or recover the cells for further analysis. |
|||
 293/GFP Cell Line |
|||
| AKR-200 | Cell Biolabs | 1 vial | EUR 572 |
|
Description: 293/GFP Cell Line stably expresses GFP and otherwise exhibits the same characteristics of the parental cell line. |
|||
 T47D/GFP Cell Line |
|||
| AKR-208 | Cell Biolabs | 1 vial | EUR 572 |
|
Description: T47D/GFP Cell Line stably expresses GFP and otherwise exhibits the same characteristics of the parental cell line. |
|||
 A549/GFP Cell Line |
|||
| AKR-209 | Cell Biolabs | 1 vial | EUR 572 |
|
Description: A549/GFP Cell Line stably expresses GFP and otherwise exhibits the same characteristics of the parental cell line. |
|||
 HeLa/GFP Cell Line |
|||
| AKR-213 | Cell Biolabs | 1 vial | EUR 572 |
|
Description: HeLa/GFP Cell Line stably expresses GFP and otherwise exhibits the same characteristics of the parental cell line. |
|||
 NIH3T3/GFP Cell Line |
|||
| AKR-214 | Cell Biolabs | 1 vial | EUR 572 |
|
Description: NIH3T3/GFP Cell Line stably expresses GFP and otherwise exhibits the same characteristics of the parental cell line. |
|||
 NIH3T3/Cas9 Cell Line |
|||
| AKR-5104 | Cell Biolabs | 1 vial | EUR 572 |
 293/Cas9 Cell Line |
|||
| AKR-5110 | Cell Biolabs | 1 vial | EUR 572 |
 HeLa/Cas9 Cell Line |
|||
| AKR-5111 | Cell Biolabs | 1 vial | EUR 572 |
-D-Ala-OH) Fmoc-b-(3-pyridyl)-D-Ala-OH |
|||
| B-2040.0001 | Bachem | 1.0g | EUR 273 |
|
Description: Sum Formula: C23H20N2O4; CAS# [142994-45-4] |
|||
Fmoc-b-(3-pyridyl)-D-Ala-OH |
|||
| B-2040.0005 | Bachem | 5.0g | EUR 998 |
|
Description: Sum Formula: C23H20N2O4; CAS# [142994-45-4] |
|||
-D-Ala-OH) Fmoc-b-(2-thienyl)-D-Ala-OH |
|||
| B-2120.0001 | Bachem | 1.0g | EUR 309 |
|
Description: Sum Formula: C22H19NO4S; CAS# [201532-42-5] |
|||
Fmoc-b-(2-thienyl)-D-Ala-OH |
|||
| B-2120.0005 | Bachem | 5.0g | EUR 1143 |
|
Description: Sum Formula: C22H19NO4S; CAS# [201532-42-5] |
|||
-D-Ala-OH) Fmoc-b-(2-quinolyl)-D-Ala-OH |
|||
| B-3170.0250 | Bachem | 250.0mg | EUR 441 |
|
Description: Sum Formula: C27H22N2O4; CAS# [214852-58-1] |
|||
Fmoc-b-(2-quinolyl)-D-Ala-OH |
|||
| B-3170.1000 | Bachem | 1.0g | EUR 1276 |
|
Description: Sum Formula: C27H22N2O4; CAS# [214852-58-1] |
|||
-D-Ala-OH) Fmoc-b-(3-benzothienyl)-D-Ala-OH |
|||
| B-3435.0001 | Bachem | 1.0g | EUR 334 |
|
Description: Sum Formula: C26H21NO4S; CAS# [177966-61-9] |
|||
Fmoc-b-(3-benzothienyl)-D-Ala-OH |
|||
| B-3435.0005 | Bachem | 5.0g | EUR 1240 |
|
Description: Sum Formula: C26H21NO4S; CAS# [177966-61-9] |
|||
-Ala(Boc)-OH) Fmoc-b-(1-piperazinyl)-Ala(Boc)-OH |
|||
| B-3725.0250 | Bachem | 250.0mg | EUR 383 |
|
Description: Sum Formula: C27H33N3O6; CAS# [313052-20-9] |
|||
Fmoc-b-(1-piperazinyl)-Ala(Boc)-OH |
|||
| B-3725.1000 | Bachem | 1.0g | EUR 1088 |
|
Description: Sum Formula: C27H33N3O6; CAS# [313052-20-9] |
|||
 Fmoc-b-azido-D-Aib-OH · BHA |
|||
| B-4535.0001 | Bachem | 1.0g | EUR 705 |
|
Description: Sum Formula: C19H18N4O4·C13H13N; CAS# [1926163-91-8] net |
|||
 MagIso Pan Monocyte Cell Isolation Kit, Human |
|||
| WHK-B021 | Creative Diagnostics | 20 tests, 200 tests | Ask for price |
, Trial Size) CytoSelect 96-Well Cell Transformation Assay (Cell Recovery Compatible, Fluorometric), Trial Size |
|||
| CBA-140-T | Cell Biolabs | 24 assays | EUR 456 |
|
Description: CytoSelect 96-Well Cell Transformation Assays (Cell Recovery Compatible) provide a robust system for detecting transformed cells, screening cell transformation inhibitors, and determining in vitro drug sensitivity. A proprietary modified soft agar matrix allows you to either quantify cells using the included fluorescent dye, or recover the cells for further analysis. |
|||
 Collagen-based Cell Contraction Assay |
|||
| CBA-201 | Cell Biolabs | 24 assays | EUR 485 |
|
Description: Cell Biolabs? Collagen-based Contraction Assay Kit provides a simple system to assess cell contractivity in vitro and screen cell contraction mediators. Each kit provides sufficient quantities to perform up to 24 assays in a 24-well plate. The kit can be also used in culturing cells in 3D collagen matrix. |
|||
 CytoSelect MTT Cell Proliferation Assay |
|||
| CBA-252 | Cell Biolabs | 960 assays | EUR 409 |
|
Description: Cell Biolabs? CytoSelect MTT Cell Proliferation Assay provides a colorimetric format for measuring and monitoring cell proliferation. The kit contains sufficient reagents for the evaluation of 960 assays in 96-well plates or 192 assays in 24-well plates. Cells can be plated and then treated with compounds or agents that affect proliferation. Cells are then detected with the proliferation reagent, which is converted in live cells from the yellow tetrazole MTT to the purple formazan form by a cellular reductase (Figure 1). An increase in cell proliferation is accompanied by an increased signal, while a decrease in cell proliferation (and signal) can indicate the toxic effects of compounds or suboptimal culture conditions. The assay principles are basic and can be applied to most eukaryotic cell lines, including adherent and non-adherent cells and certain tissues. This cell proliferation reagent can be used to detect proliferation in bacteria, yeast, fungi, protozoa as well as cultured mammalian and piscine cells. |
|||
 SKOV-3/Luc Cell Line |
|||
| AKR-232 | Cell Biolabs | 1 vial | EUR 572 |
|
Description: SKOV-3/Luc Cell Line stably expresses luciferase and otherwise exhibits the same characteristics of the parental cell line. |
|||
 MCF-7/Luc Cell Line |
|||
| AKR-234 | Cell Biolabs | 1 vial | EUR 572 |
|
Description: MCF-7/Luc Cell Line stably expresses luciferase and otherwise exhibits the same characteristics of the parental cell line. |
|||
 OVCAR-5/RFP Cell Line |
|||
| AKR-254 | Cell Biolabs | 1 vial | EUR 572 |
|
Description: OVCAR-5/RFP Cell Line stably expresses RFP and otherwise exhibits the same characteristics of the parental cell line. |
|||
3-b-D)-OH) Fmoc-Asn(GlcNAc(Ac)3-b-D)-OH |
|||
| B-2480.0100 | Bachem | 100.0mg | EUR 587 |
|
Description: Sum Formula: C33H37N3O13; CAS# [131287-39-3] |
|||
Fmoc-Asn(GlcNAc(Ac)3-b-D)-OH |
|||
| B-2480.0250 | Bachem | 250.0mg | EUR 1143 |
|
Description: Sum Formula: C33H37N3O13; CAS# [131287-39-3] |
|||
-Gly-OH) Fmoc-N-(N-b-Boc-aminoethyl)-Gly-OH |
|||
| B-3285.0001 | Bachem | 1.0g | EUR 454 |
|
Description: Sum Formula: C24H28N2O6; CAS# [141743-15-9] |
|||
Fmoc-N-(N-b-Boc-aminoethyl)-Gly-OH |
|||
| B-3285.0005 | Bachem | 5.0g | EUR 1698 |
|
Description: Sum Formula: C24H28N2O6; CAS# [141743-15-9] |
|||
3-b-D)-OH) Fmoc-Ser(GlcNAc(Ac)3-b-D)-OH |
|||
| B-3865.0025 | Bachem | 25.0mg | EUR 265 |
|
Description: Sum Formula: C32H36N2O13; CAS# [160067-63-0] |
|||
Fmoc-Ser(GlcNAc(Ac)3-b-D)-OH |
|||
| B-3865.0100 | Bachem | 100.0mg | EUR 735 |
|
Description: Sum Formula: C32H36N2O13; CAS# [160067-63-0] |
|||
Fmoc-Ser(GlcNAc(Ac)3-b-D)-OH |
|||
| B-3865.0250 | Bachem | 250.0mg | EUR 1438 |
|
Description: Sum Formula: C32H36N2O13; CAS# [160067-63-0] |
|||
3-b-D)-OH) Fmoc-Ser(GalNAc(Ac)3-b-D)-OH |
|||
| B-4235.0025 | Bachem | 25.0mg | EUR 265 |
|
Description: Sum Formula: C32H36N2O13; CAS# [1676104-71-4] |
|||
Fmoc-Ser(GalNAc(Ac)3-b-D)-OH |
|||
| B-4235.0100 | Bachem | 100.0mg | EUR 735 |
|
Description: Sum Formula: C32H36N2O13; CAS# [1676104-71-4] |
|||
Fmoc-Ser(GalNAc(Ac)3-b-D)-OH |
|||
| B-4235.0250 | Bachem | 250.0mg | EUR 1438 |
|
Description: Sum Formula: C32H36N2O13; CAS# [1676104-71-4] |
|||
3-b-D)-OH) Fmoc-Thr(GalNAc(Ac)3-b-D)-OH |
|||
| B-4240.0025 | Bachem | 25.0mg | EUR 277 |
|
Description: Sum Formula: C33H38N2O13; CAS# [133575-43-6] |
|||
Fmoc-Thr(GalNAc(Ac)3-b-D)-OH |
|||
| B-4240.0100 | Bachem | 100.0mg | EUR 770 |
|
Description: Sum Formula: C33H38N2O13; CAS# [133575-43-6] |
|||
Fmoc-Thr(GalNAc(Ac)3-b-D)-OH |
|||
| B-4240.0250 | Bachem | 250.0mg | EUR 1510 |
|
Description: Sum Formula: C33H38N2O13; CAS# [133575-43-6] |
|||
3-b-D)-OH) Fmoc-Thr(GlcNAc(Ac)3-b-D)-OH |
|||
| B-4245.0025 | Bachem | 25.0mg | EUR 277 |
|
Description: Sum Formula: C33H38N2O13; CAS# [160168-40-1] |
|||
Fmoc-Thr(GlcNAc(Ac)3-b-D)-OH |
|||
| B-4245.0100 | Bachem | 100.0mg | EUR 770 |
|
Description: Sum Formula: C33H38N2O13; CAS# [160168-40-1] |
|||
Fmoc-Thr(GlcNAc(Ac)3-b-D)-OH |
|||
| B-4245.0250 | Bachem | 250.0mg | EUR 1510 |
|
Description: Sum Formula: C33H38N2O13; CAS# [160168-40-1] |
|||
 CytoSelect 24-well Cell Invasion, Fluorometric |
|||
| CBA-111 | Cell Biolabs | 12 assays | EUR 595 |
|
Description: The ability of malignant tumor cells to invade normal surrounding tissue contributes in large part to the morbidity and mortality of cancers. Cell invasion requires several distinct cellular functions including adhesion, motility, detachment, and extracellular matrix proteolysis. Our CytoSelect Cell Invasion Assays utilize precoated inserts to assay the invasive properties of tumor cells. Invasive cells can be quantified in 24-well plates on either a standard microplate reader or a fluorescence plate reader. Inserts are precoated on the top of the membrane with ECM matrix gel (basement membrane), a protein mix isolated from EHS tumor cells. |
|||
 CytoSelect 96-well Cell Invasion, Fluorometric |
|||
| CBA-112 | Cell Biolabs | 96 assays | EUR 757 |
|
Description: The ability of malignant tumor cells to invade normal surrounding tissue contributes in large part to the morbidity and mortality of cancers. Cell invasion requires several distinct cellular functions including adhesion, motility, detachment, and extracellular matrix proteolysis. Our CytoSelect 96-Well Cell Invasion Assays utilize precoated inserts to assay the invasive properties of tumor cells. Invasive cells can be quantified in 96-well plates on a fluorescence plate reader. Inserts are precoated on the top of the membrane with Basement Membrane, an ECM protein mix isolated from EHS tumor cells. |
|||
 Radius 24-Well Cell Migration Assay |
|||
| CBA-125 | Cell Biolabs | 24 assays | EUR 502 |
|
Description: The Radius Cell Migration Assay provides a unique alternative to conventional cell migration assays using the Boyden chamber. Unlike Boyden chamber assays which may only be analyzed at endpoint, the Radius assay uses a proprietary cell culture plate containing a carefully-defined biocompatible hydrogel (Radius gel) spot centralized at the bottom of each well. When cells are seeded in the well, they will attach everywhere except on the Radius gel, creating a cell-free zone. Following cell seeding the Radius gel is removed, allowing migratory cells to move across the area and close the gap. |
|||
Radius 24-Well Cell Migration Assay |
|||
| CBA-125-5 | Cell Biolabs | 5 x 24 assays | EUR 1969 |
|
Description: The Radius Cell Migration Assay provides a unique alternative to conventional cell migration assays using the Boyden chamber. Unlike Boyden chamber assays which may only be analyzed at endpoint, the Radius assay uses a proprietary cell culture plate containing a carefully-defined biocompatible hydrogel (Radius gel) spot centralized at the bottom of each well. When cells are seeded in the well, they will attach everywhere except on the Radius gel, creating a cell-free zone. Following cell seeding the Radius gel is removed, allowing migratory cells to move across the area and close the gap. |
|||
 Radius 96-Well Cell Migration Assay |
|||
| CBA-126 | Cell Biolabs | 96 assays | EUR 572 |
|
Description: The Radius Cell Migration Assay provides a unique alternative to conventional cell migration assays using the Boyden chamber. Unlike Boyden chamber assays which may only be analyzed at endpoint, the Radius assay uses a proprietary cell culture plate containing a carefully-defined biocompatible hydrogel (Radius gel) spot centralized at the bottom of each well. When cells are seeded in the well, they will attach everywhere except on the Radius gel, creating a cell-free zone. Following cell seeding the Radius gel is removed, allowing migratory cells to move across the area and close the gap. |
|||
Radius 96-Well Cell Migration Assay |
|||
| CBA-126-5 | Cell Biolabs | 5 x 96 assays | EUR 2248 |
|
Description: The Radius Cell Migration Assay provides a unique alternative to conventional cell migration assays using the Boyden chamber. Unlike Boyden chamber assays which may only be analyzed at endpoint, the Radius assay uses a proprietary cell culture plate containing a carefully-defined biocompatible hydrogel (Radius gel) spot centralized at the bottom of each well. When cells are seeded in the well, they will attach everywhere except on the Radius gel, creating a cell-free zone. Following cell seeding the Radius gel is removed, allowing migratory cells to move across the area and close the gap. |
|||
 Radius 384-Well Cell Migration Assay |
|||
| CBA-127 | Cell Biolabs | 384 assays | EUR 601 |
|
Description: The Radius Cell Migration Assay provides a unique alternative to conventional cell migration assays using the Boyden chamber. Unlike Boyden chamber assays which may only be analyzed at endpoint, the Radius assay uses a proprietary cell culture plate containing a carefully-defined biocompatible hydrogel (Radius gel) spot centralized at the bottom of each well. When cells are seeded in the well, they will attach everywhere except on the Radius gel, creating a cell-free zone. Following cell seeding the Radius gel is removed, allowing migratory cells to move across the area and close the gap. |
|||
Radius 384-Well Cell Migration Assay |
|||
| CBA-127-5 | Cell Biolabs | 5 x 384 wells | EUR 2335 |
|
Description: The Radius Cell Migration Assay provides a unique alternative to conventional cell migration assays using the Boyden chamber. Unlike Boyden chamber assays which may only be analyzed at endpoint, the Radius assay uses a proprietary cell culture plate containing a carefully-defined biocompatible hydrogel (Radius gel) spot centralized at the bottom of each well. When cells are seeded in the well, they will attach everywhere except on the Radius gel, creating a cell-free zone. Following cell seeding the Radius gel is removed, allowing migratory cells to move across the area and close the gap. |
|||
 CytoSelect 96-well Cell Transformation Assay |
|||
| CBA-130 | Cell Biolabs | 96 assays | EUR 722 |
|
Description: Our CytoSelect 96-Well Cell Transformation Assay (Soft Agar Colony Formation) is suitable for measuring cell transformation where no downstream analysis is required. Cells are incubated in a semisolid agar medium for 7-8 days. The cells are then solubilized, lysed and detected using the included fluorescent dye in a fluorometric plate reader. |
|||
CytoSelect 96-well Cell Transformation Assay |
|||
| CBA-130-5 | Cell Biolabs | 5 x 96 assays | EUR 2886 |
|
Description: Our CytoSelect 96-Well Cell Transformation Assay (Soft Agar Colony Formation) is suitable for measuring cell transformation where no downstream analysis is required. Cells are incubated in a semisolid agar medium for 7-8 days. The cells are then solubilized, lysed and detected using the included fluorescent dye in a fluorometric plate reader. |
|||
 CytoSelect Cell Viability and Cytotoxicity Assay |
|||
| CBA-240 | Cell Biolabs | 96 assays | EUR 392 |
|
Description: The CytoSelect Cell Viability and Cytotoxicity Assay Kit provides a simple format for monitoring cell viability via metabolic activity. Live cells are detected with either MTT (colorimetric detection) or Calcein AM (fluorometric detection). Dead cells are detected by EthD-1 reagent (fluorometric). All 3 detection reagents are included, along with Saponin (a cell death initiator). Prior to the assay, cells may be treated with compounds or agents that affect cell viability. This kit is suitable for eukaryotic cells, not yeast or bacteria. |
|||
) CytoSelect Cell Proliferation Assay Reagent (Fluorometric) |
|||
| CBA-250 | Cell Biolabs | 10 mL | EUR 409 |
|
Description: Cell Biolabs? CytoSelect Cell Proliferation Assay Reagent (Fluorometric) provides a fluorometric format for measuring and monitoring cell proliferation. Cells can be plated and then treated with compounds or agents that affect proliferation. Cells are then incubated with the proliferation reagent. Upon entering metabolically active live cells, the non-fluorescent proliferation reagent is converted into a bright red fluorescent form. An increase in cell proliferation is accompanied by increased fluorescent signal, while a decrease in cell proliferation (and signal) can indicate the toxic effects of compounds or suboptimal culture conditions. The assay principles are basic and can be applied to most eukaryotic cell lines, including adherent and non-adherent cells and certain tissues. This cell proliferation reagent can be used to detect proliferation in bacteria, yeast, fungi, protozoa as well as cultured mammalian and piscine cells. The kit contains sufficient reagents for the evaluation of 960 assays in ten 96-well plates or 192 assays in eight 24-well plates. |
|||
 CytoSelect BrdU Cell Proliferation ELISA Kit |
|||
| CBA-251 | Cell Biolabs | 96 assays | EUR 531 |
|
Description: The CytoSelect BrdU Cell Proliferation ELISA Kit detects BrdU incorporated into cellular DNA during cell proliferation using an anti-BrdU antibody. When cells are incubated in media containing BrdU, the pyrimidine analog is incorporated in place of thymidine into the newly synthesized DNA of proliferating cells. Once the labeling media is removed, the cells are fixed and the DNA is denatured in one step with a fix/denature solution (denaturation of the DNA is necessary to improve the accessibility of the incorporated BrdU for detection). Then an anti-BrdU mouse monoclonal antibody is added followed by an HRP conjugated secondary antibody to detect the incorporated BrdU. The magnitude of the absorbance for the developed color is proportional to the quantity of BrdU incorporated into cells and can be directly correlated to cell proliferation. |
|||
) CytoSelect Cell Proliferation Assay Reagent (Colorimetric) |
|||
| CBA-253 | Cell Biolabs | 10 mL | EUR 409 |
|
Description: Cell Biolabs? CytoSelect WST-1 Cell Proliferation Assay Reagent provides a colorimetric format for measuring and monitoring cell proliferation. The 10 mL volume is sufficient for the evaluation of 960 assays in ten 96-well plates or 192 assays in eight 24-well plates. Cells can be plated and then treated with compounds or agents that affect proliferation. Cells are then detected with the proliferation reagent, which is converted in live cells from WST-1 to the formazan form in the presence of cellular NADH and an electron mediator. An increase in cell proliferation is accompanied by increased signal, while a decrease in cell proliferation (and signal) can indicate the toxic effects of compounds or suboptimal culture conditions. The assay principles are basic and can be applied to most eukaryotic cell lines, including adherent and non-adherent cells and certain tissues. This cell proliferation reagent can be used to detect proliferation in bacteria, yeast, fungi, protozoa as well as cultured mammalian and piscine cells. |
|||
 Radius 48-Well Cell Migration Assay |
|||
| CBA-5037 | Cell Biolabs | 48 assays | EUR 519 |
|
Description: The Radius Cell Migration Assay provides a unique alternative to conventional cell migration assays using the Boyden chamber. Unlike Boyden chamber assays which may only be analyzed at endpoint, the Radius assay uses a proprietary cell culture plate containing a carefully-defined biocompatible hydrogel (Radius gel) spot centralized at the bottom of each well. When cells are seeded in the well, they will attach everywhere except on the Radius gel, creating a cell-free zone. Following cell seeding the Radius gel is removed, allowing migratory cells to move across the area and close the gap. |
|||
Radius 48-Well Cell Migration Assay |
|||
| CBA-5037-5 | Cell Biolabs | 5 x 48 assays | EUR 2045 |
|
Description: The Radius Cell Migration Assay provides a unique alternative to conventional cell migration assays using the Boyden chamber. Unlike Boyden chamber assays which may only be analyzed at endpoint, the Radius assay uses a proprietary cell culture plate containing a carefully-defined biocompatible hydrogel (Radius gel) spot centralized at the bottom of each well. When cells are seeded in the well, they will attach everywhere except on the Radius gel, creating a cell-free zone. Following cell seeding the Radius gel is removed, allowing migratory cells to move across the area and close the gap. |
|||
) Hematoxylin, Weigert's Iron (Part B) |
|||
| HWI-B-250 | ScyTek Laboratories | 250 ml | EUR 72 |
-Ala-OH) Fmoc-b-(7-methoxy-coumarin-4-yl)-Ala-OH |
|||
| B-3740.0500 | Bachem | 500.0mg | EUR 345 |
|
Description: Sum Formula: C28H23NO7; CAS# [524698-40-6] |
|||
Fmoc-b-(7-methoxy-coumarin-4-yl)-Ala-OH |
|||
| B-3740.1000 | Bachem | 1.0g | EUR 605 |
|
Description: Sum Formula: C28H23NO7; CAS# [524698-40-6] |
|||
 Macrophage/Monocyte Antibody |
|||
| abx415014-025mg | Abbexa | 0.25 mg | EUR 648 |
Macrophage/Monocyte Antibody |
|||
| abx415015-25ug | Abbexa | 25 ug | EUR 300 |
 Monocyte/Macrophage Antibody |
|||
| abx415176-025mg | Abbexa | 0.25 mg | EUR 592 |
 Monocyte/Granulocyte Antibody |
|||
| abx415381-01mg | Abbexa | 0.1 mg | EUR 453 |
 CytoSelect 24-well Cell Invasion Assay, Colorimetric |
|||
| CBA-110 | Cell Biolabs | 12 assays | EUR 595 |
|
Description: The ability of malignant tumor cells to invade normal surrounding tissue contributes in large part to the morbidity and mortality of cancers. Cell invasion requires several distinct cellular functions including adhesion, motility, detachment, and extracellular matrix proteolysis. Our CytoSelect Cell Invasion Assays utilize precoated inserts to assay the invasive properties of tumor cells. Invasive cells can be quantified in 24-well plates on either a standard microplate reader or a fluorescence plate reader. Inserts are precoated on the top of the membrane with ECM matrix gel (basement membrane), a protein mix isolated from EHS tumor cells. |
|||
 CytoSelect 24-well Collagen Cell Invasion, Colorimetric |
|||
| CBA-110-COL | Cell Biolabs | 12 assays | EUR 595 |
|
Description: The ability of malignant tumor cells to invade normal surrounding tissue contributes in large part to the morbidity and mortality of cancers. Cell invasion requires several distinct cellular functions including adhesion, motility, detachment, and extracellular matrix proteolysis. Our CytoSelect Cell Invasion Assays utilize precoated inserts to assay the invasive properties of tumor cells. Invasive cells can be quantified in 24-well plates on either a standard microplate reader or a fluorescence plate reader. Inserts are precoated on the top of the membrane with Collagen I. |
|||
Many analysis teams at the moment are investigating the underlying mechanisms and the way in which through which the effector proteins translocated by this machine subvert host defences. This overview supplies an outline of our present information about sort VI secretion, specializing in gene regulation, parts of the secretion machine, substrate secretion and the mobile penalties for the host cell.